Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Dennis J. Grab"'
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Anaplasma phagocytophilum, a tick-borne obligately intracellular bacterium of neutrophils, causes human granulocytic anaplasmosis. Ankyrin A (AnkA), an effector protein with multiple ankyrin repeats (AR) is injected via type IV-secretion into the hos
Externí odkaz:
https://doaj.org/article/4a7ef48f2cbf447fa9c937a9c3346678
Autor:
Tatiana F. R. Costa, Amy Goundry, Alexandre Morrot, Dennis J. Grab, Jeremy C. Mottram, Ana Paula C. A. Lima
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 656 (2022)
The protozoan Trypanosoma brucei rhodesiense causes Human African Trypanosomiasis, also known as sleeping sickness, and penetrates the central nervous system, leading to meningoencephalitis. The Cathepsin L-like cysteine peptidase of T. b. rhodesiens
Externí odkaz:
https://doaj.org/article/db606d15b4684e9fa5b54c2e3cc234f7
Autor:
J. Stephen Dumler, Kyoung-Seong Choi, Jose Carlos Garcia-Garcia, Nicole S. Barat, Diana G. Scorpio, Justin W. Garyu, Dennis J. Grab, Johan S. Bakken
Publikováno v:
Emerging Infectious Diseases, Vol 11, Iss 12, Pp 1828-1834 (2005)
Human granulocytic anaplasmosis is a tickborne rickettsial infection of neutrophils caused by Anaplasma phagocytophilum. The human disease was first identified in 1990, although the pathogen was defined as a veterinary agent in 1932. Since 1990, US c
Externí odkaz:
https://doaj.org/article/0070340c33864241ad529bae57583cff
Autor:
Andrés F Londoño, Jennifer M Farner, Marlon Dillon, Dennis J Grab, Yuri Kim, Diana G Scorpio, J Stephen Dumler
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 2, p e0011993 (2024)
Spotted fever group rickettsiae are tick-borne obligate intracellular bacteria that infect microvascular endothelial cells. Humans and mammalian infection results in endothelial cell barrier dysfunction and increased vascular permeability. We previou
Externí odkaz:
https://doaj.org/article/303aaa7626214e9fa6ff891afd627703
Autor:
Yuri Kim, Emily G. Clemens, Jennifer M. Farner, Andres Londono-Barbaran, Dennis J. Grab, J. Stephen Dumler
Publikováno v:
Biochemical and Biophysical Research Communications. 663:96-103
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::533d6517b6c2cde6a2bd02f22f3e2a8c
https://doi.org/10.1016/j.bbrc.2023.04.045
https://doi.org/10.1016/j.bbrc.2023.04.045
Autor:
Raquel S. S. Laires, Amy Goundry, Dennis J Grab, Ana Paula C. A. Lima, Tatiana F. R. Costa, Jeremy C. Mottram, David Jessula Levy, Carlos Novo
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 6, p e0009526 (2021)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases
Trypanosoma brucei rhodesiense is one of the causative agents of Human African Trypanosomiasis (HAT), known as sleeping sickness. The parasite invades the central nervous system and causes severe encephalitis that is fatal if left untreated. We have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fc942a2d961fe9fa1d79e67930bcd79
https://eprints.gla.ac.uk/245376/1/245376.pdf
https://eprints.gla.ac.uk/245376/1/245376.pdf
Autor:
David Gozal, Hu Huang, Abdelnaby Khalyfa, Dennis J. Grab, Anton Lennikov, Madhu Sudhana Saddala, Lijuan Fan
Publikováno v:
FASEB J
We report that placental growth factor (PlGF) negatively affects the endothelial cell (EC) barrier function through a novel regulatory mechanism. The PlGF mAb promotes (but recombinant protein disrupts) EC barrier function, thus affecting the barrier
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2bbb788093ca6a973f3d55770220a51
https://doi.org/10.1096/fj.201901353r
https://doi.org/10.1096/fj.201901353r
Autor:
Yi-Pin Lin, Fuming Zhang, Preeti Singh, Quentin Bernard, Darrin R. Akins, J. Stephen Dumler, Thomas M. Hart, Utpal Pal, Kai Zhnag, Yuri Kim, Robert J. Linhardt, Lucy Hritzo, Chrysoula Kitsou, Vipin Singh Rana, Dennis J Grab, Sandhya Bista, Xiuli Yang
Publikováno v:
J Infect Dis
Borrelia burgdorferi conserved gene products BB0406 and BB0405, members of a common B. burgdorferi paralogous gene family, share 59% similarity. Although both gene products can function as potential porins, only BB0405 is essential for infection. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0de9bea9471c619b4a533e49680f5ce4
https://europepmc.org/articles/PMC7137894/
https://europepmc.org/articles/PMC7137894/
Publikováno v:
The Journal of Immunology. 204:82.24-82.24
Detection of antibodies by ELISA for verifying exposure to dengue virus (DENV) and Zika virus (ZIKV) has been a challenge. Point-of-care (POC) diagnostics with detection of very low concentrations of viral antigens would improve critical disease stag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::131c205c1a531a4285820a21de3c222c
https://doi.org/10.4049/jimmunol.204.supp.82.24
https://doi.org/10.4049/jimmunol.204.supp.82.24
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Placental growth factor (PlGF or PGF), a member of the vascular endothelial growth factor (VEGF) sub-family, plays a crucial role in pathological angiogenesis and inflammation. However, the underlying molecular mechanisms that PlGF mediates regarding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e60e58ea03288cdadb4ef0089fabf1cd
http://europepmc.org/articles/PMC6233167
http://europepmc.org/articles/PMC6233167