Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Dennis I. Ruggles"'
Autor:
Saura C. Sahu, Dennis I. Ruggles, Larry H. Garthoff, Thomas J. Sobotka, Martin G. Robl, Stuart J. Chirtel, Thomas J. Flynn
Publikováno v:
Journal of Applied Toxicology. 28:765-772
Deoxynivalenol (DON) is a mycotoxin food contaminant found in several cereal grains. The literature on the liver toxicity of DON in vivo is conflicting and does not clearly characterize its hepatotoxic effects. Cultured rat liver clone-9 cells were u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c9fa2c84ebd0fc96ec2f68e4ea49e50
https://doi.org/10.1002/jat.1337
https://doi.org/10.1002/jat.1337
Autor:
M. Ramos-Valle, T.N. Black, Robert L. Sprando, Nicholas Olejnik, Thomas F.X. Collins, Dennis I. Ruggles
Publikováno v:
Food and Chemical Toxicology. 45:1606-1613
Acute toxicity of a single oral dose of sodium arsenite (As), administered in half and half cream (HH), was assessed in male and non-pregnant female rats (0.41, 4.1, 41.0 and 410.0 mg/kg body weight) and pregnant rats (0.41, 4.1 and 41.0 mg/kg body w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08ca2b9c9960aea24245c594b1f67749
https://doi.org/10.1016/j.fct.2007.02.026
https://doi.org/10.1016/j.fct.2007.02.026
Autor:
T.N. Black, J.I. Rorie, Dennis I. Ruggles, Nicholas Olejnik, Robert L. Sprando, Robert M. Eppley, Fred A. Hines, Thomas F.X. Collins
Publikováno v:
Food and Chemical Toxicology. 44:747-757
Deoxynivalenol (DON, vomitoxin), is one of the most common contaminants of cereal grains world-wide. The effects of DON on fetal development were assessed in Charles River Sprague–Dawley rats. Pregnant female rats were gavaged once daily with DON a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51460f65f44083254c531f48814480b7
https://doi.org/10.1016/j.fct.2005.10.007
https://doi.org/10.1016/j.fct.2005.10.007
Autor:
T.N. Black, Robert L. Sprando, Robert M. Eppley, J.I. Rorie, Nicholas Olejnik, Thomas F.X. Collins, Dennis I. Ruggles
Publikováno v:
Food and Chemical Toxicology. 43:623-635
The effect of deoxynivalenol (DON) exposure on male reproductive function was assessed in the rat. Male rats were divided into a control group (n=15 rats) and four treatment groups (0.5 mg/kg, n=15; 1.0 mg/kg, n=15; 2.5 mg/kg, n=15; and 5.0 mg/kg DON
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e40ffddfe63d878b17f23e3b6603fc71
https://doi.org/10.1016/j.fct.2004.12.017
https://doi.org/10.1016/j.fct.2004.12.017
Autor:
Dennis I. Ruggles, T.N. Black, Erich Grundel, Nicholas Olejnik, Robert L. Sprando, Thomas F.X. Collins
Publikováno v:
Food and Chemical Toxicology. 42:917-924
This study was conducted to characterize the effect of androstenedione on estrous cyclicity, mating behavior and fetal development. Thirty-day old rats received corn oil alone or androstenedione (in corn oil) at one of four concentrations (0, 1.0, 5.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f6349c0253cb7b7bf819b724e859563
https://doi.org/10.1016/j.fct.2004.01.015
https://doi.org/10.1016/j.fct.2004.01.015
Autor:
Paddy Wiesenfeld, Dennis I. Ruggles, Uma S. Babu, T.N. Black, Robert L. Sprando, Thomas J. Flynn, Thomas F.X. Collins
Publikováno v:
Food and Chemical Toxicology. 41:835-840
Gestation day 9.5 rat embryos were cultured for 45 h in serum obtained from pregnant rats that had been fed throughout gestation with either a control diet (based on the AIN-93 formulation), a diet supplemented with flaxseed (20% or 40%, w/w), or a d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0645b9438e31072cfa9441bb7e3b2751
https://doi.org/10.1016/s0278-6915(03)00034-6
https://doi.org/10.1016/s0278-6915(03)00034-6
Autor:
Dennis I. Ruggles, T.N. Black, Nicholas Olejnik, Thomas F.X. Collins, M.J. Ames, Robert L. Sprando, M.E. Shackelford, J.I. Rorie
Publikováno v:
Food and Chemical Toxicology. 39:867-876
Sodium fluoride (NaF) has been used to fluoridate drinking water in the United States since the mid 1940s. Because of the lack of reliable studies on the multigeneration effects of the compound, NaF (0, 25, 100, 175 or 250 ppm in drinking water) was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bd0cc928da4f34f7606a107e724c9fa
https://doi.org/10.1016/s0278-6915(01)00033-3
https://doi.org/10.1016/s0278-6915(01)00033-3
Autor:
Deborah K. Hansen, James B. LaBorde, Nicholas Olejnik, Thomas F.X. Collins, M.A. Bryant, Dennis I. Ruggles, Robert M. Eppley, J.I. Rorie, Paul C. Howard, M.W. Trucksess, Robert L. Sprando, M.E. Shackelford, T.N. Black
Publikováno v:
Food and Chemical Toxicology. 36:397-408
Fumonisin B1 (FB1), the major mycotoxin from Fusarium moniliforme, has been implicated as a causative agent in several animal and human diseases. Despite animal toxicity studies and human epidemiological studies of FB1, knowledge of its reproductive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9eb6d35776ce764a786621f989d893b0
https://doi.org/10.1016/s0278-6915(97)00170-1
https://doi.org/10.1016/s0278-6915(97)00170-1
Publikováno v:
Toxicology and Industrial Health. 12:45-57
The pyrazolone dye Orange B was given by gavage to pregnant Osborne- Mendel rats throughout gestation. Dose levels of 0, 15, 30, 100, 200, 400, or 700 mglkg body weight were given daily. On gestation day 20, the females were killed and cesarean secti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2ad73e55699208b4b69c18150d0b083
https://doi.org/10.1177/074823379601200102
https://doi.org/10.1177/074823379601200102
Autor:
Thomas F.X. Collins, Dennis I. Ruggles, M.F. Balmer, M.J. Ames, Robert L. Sprando, T.N. Black, J.J. Welsh, Nicholas Olejnik, M.E. Shackelford
Publikováno v:
Food and Chemical Toxicology. 33:951-960
Despite the chronic exposure of the US population to fluoridated drinking water since the 1940s, existing studies have been judged inadequate to determine any potential reproductive or developmental hazard. This study was conducted to determine the e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddb296b072d6bf1186fcf3dc770a9711
https://doi.org/10.1016/0278-6915(95)00066-b
https://doi.org/10.1016/0278-6915(95)00066-b