Zobrazeno 1 - 10
of 129
pro vyhledávání: '"Dennis Hsu"'
Autor:
Akshit Chitkara, Muhammad Bakhtiar, Ibrahim Halil Sahin, Dennis Hsu, Janie Zhang, FNU Anamika, Mahnoor Mahnoor, Rabeea Ahmed, Sepideh Gholami, Anwaar Saeed
Publikováno v:
Current Oncology, Vol 30, Iss 9, Pp 8266-8277 (2023)
Recent trials provide evidence that HER2 is a potential new target for patients with colorectal cancer. While HER2-positive tumors do not show a very encouraging response to anti-HER2-positive agents like trastuzumab alone, promising results have bee
Externí odkaz:
https://doaj.org/article/623d0fc15e964f76a85e8bcf636a880b
Autor:
Joseph Carver, Thomas S Dexheimer, Dennis Hsu, Meng-Tzu Weng, Jordan L Smith, Rajarshi Guha, Ajit Jadhav, Anton Simeonov, Ji Luo
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e103836 (2014)
Mutations in the Ras family of small GTPases, particularly KRAS, occur at high frequencies in cancer and represent a major unmet therapeutic need due to the lack of effective targeted therapies. Past efforts directed at inhibiting the activity of the
Externí odkaz:
https://doaj.org/article/fa1c144e0dc34bbdaa7d17b1fac6ae50
Autor:
Ibrahim Halil Sahin, Janie Zhang, Turcin Saridogan, Vikram Gorantla, John Rhree, Monica Malhotra, Roby Thomas, Dennis Hsu, Anwaar Saeed
Publikováno v:
JCO Oncology Practice. 19:251-259
Immune checkpoint inhibitors (ICIs) have revolutionized the treatment paradigm of mismatch repair–deficient/microsatellite instability-high (MMMR-D/MSI-H) colorectal cancer (CRC). Unique molecular features of MMR-D/MSI-H CRC with frameshift alterat
Autor:
Lisa B. Earnest-Noble, Dennis Hsu, Siyu Chen, Hosseinali Asgharian, Mandayam Nandan, Maria C. Passarelli, Hani Goodarzi, Sohail F. Tavazoie
Publikováno v:
Nature Cancer. 3:1484-1497
The human genome contains 61 codons encoding 20 amino acids. Synonymous codons representing a given amino acid are decoded by a set of transfer RNAs (tRNAs) called isoacceptors. We report the surprising observation that two isoacceptor tRNAs that dec
Autor:
Mike Armour, Jacob George, Nathan A. Johnson, Callum J. Baker, Shelley E. Keating, Daniel A. Hackett, Loren Barr, Angelo Sabag, Dennis Hsu-Tung Chang, Alex Armstrong, Stephen M. Twigg
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 107:862-881
Context Non-alcoholic fatty liver disease, characterized by excess fat accumulation in the liver, is considered the hepatic manifestation of metabolic syndrome. Recent findings have shown that high-intensity interval training (HIIT) can reduce liver
Autor:
Jia Li, Jieping Zhang, Dennis Hsu-Tung Chang, Deep Jyoti Bhuyan, Seungyeon Yeon, Chun Guang Li, Xiasen Jiang, Sai Wang Seto, Yanfang Zheng, Xian Zhou, Wenzhen Yu
Publikováno v:
Journal of Neurochemistry. 156:249-261
Neuroinflammation is believed to play a primary role in the pathogenesis of most neurodegenerative diseases including Alzheimer's disease, Parkinson's disease and schizophrenia. Currently, suitable in vitro neuroinflammation models for studying cellu
Autor:
S Y Yeon, Ning Wang, Gabriel H. H. Chan, Mitchell Low, Dennis Hsu-Tung Chang, Jian-Xun Liu, Sai Wang Seto, Hosen Kiat
Publikováno v:
Evidence-based Complementary and Alternative Medicine : eCAM
Evidence-Based Complementary and Alternative Medicine, Vol 2020 (2020)
Evidence-Based Complementary and Alternative Medicine, Vol 2020 (2020)
Background. Sailuotong (SLT) is a standardized three-herb formulation consisting of extracts of Panax ginseng, Ginkgo biloba, and Crocus sativus for the treatment of vascular dementia (VaD). Although SLT has been shown to increase cerebral blood flow
Publikováno v:
Phytotherapy Research. 34:1889-1901
Obsessive-compulsive disorder (OCD) is a relatively prevalent mental disorder that poses significant health burdens on the community. Although current conventional medications have good efficacy for many patients, they can elicit a range of associate
Publikováno v:
Advances in Integrative Medicine. 7:23-28
Background Omega-3 fatty acids are associated with beneficial health outcomes including reduced cardiovascular disease. Few individuals meet their requirements for omega 3 fatty acids through foods. Supplementation may be a viable option. Aim This op
Autor:
Ronan Wenhan Hsieh, Matthew Lee, Devin Johnson, Chenxin Zhang, Jee-Young Moon, Dennis Hsu, Ana Acuna-Villaorduna, Chaoyuan Kuang
Publikováno v:
Journal of Clinical Oncology. 41:135-135
135 Background: Regorafenib (rego) is a multikinase inhibitor approved for use in metastatic colorectal cancer (mCRC). No predictive biomarkers have been identified for rego. We conducted a real-world multi-institutional retrospective study to identi