Zobrazeno 1 - 10
of 396
pro vyhledávání: '"Dennis G. Hall"'
Autor:
Jason P. G. Rygus, Dennis G. Hall
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract Organocatalytic strategies for the direct activation of hydroxy-containing compounds have paled in comparison to those applicable to carbonyl compounds. To this end, boronic acids have emerged as valuable catalysts for the functionalization
Externí odkaz:
https://doaj.org/article/7b42fe7d56f249759cb1e21f216de702
Autor:
Sams M. A. Sadat, Melinda Wuest, Igor M. Paiva, Sirazum Munira, Nasim Sarrami, Forughalsadat Sanaee, Xiaoyan Yang, Marco Paladino, Ziyad Binkhathlan, Feridoun Karimi-Busheri, Gary R. Martin, Frank R. Jirik, David Murray, Armin M. Gamper, Dennis G. Hall, Michael Weinfeld, Afsaneh Lavasanifar
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Inhibition of the DNA repair enzyme polynucleotide kinase/phosphatase (PNKP) increases the sensitivity of cancer cells to DNA damage by ionizing radiation (IR). We have developed a novel inhibitor of PNKP, i.e., A83B4C63, as a potential radio-sensiti
Externí odkaz:
https://doaj.org/article/ddeac58804c64cf5855aac973135ab08
Autor:
Gyeong-Hun Baeg, Dennis G. Hall, Agnieszka Ulaczyk-Lesanko, Somasundaram Jayabose, Claudio Sandoval, Haeryun Lee, Erika A. Bach, Qianxu Guo, Chang-Hong Yin, Byung Hak Kim
Supplementary Fig. S1 from A small-molecule compound identified through a cell-based screening inhibits JAK/STAT pathway signaling in human cancer cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::935f6e4244df9b63086bad4bc7679eb1
https://doi.org/10.1158/1535-7163.22484498.v1
https://doi.org/10.1158/1535-7163.22484498.v1
Autor:
Gyeong-Hun Baeg, Dennis G. Hall, Agnieszka Ulaczyk-Lesanko, Somasundaram Jayabose, Claudio Sandoval, Haeryun Lee, Erika A. Bach, Qianxu Guo, Chang-Hong Yin, Byung Hak Kim
Inappropriate activation of JAK/STAT signaling occurs with high frequency in human cancers and is associated with cancer cell survival and proliferation. Therefore, the development of pharmacologic STAT signaling inhibitors has therapeutic potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6688fe0700d1e5981d8168d55b9367f2
https://doi.org/10.1158/1535-7163.c.6531431
https://doi.org/10.1158/1535-7163.c.6531431
Autor:
Igor Moura de Paiva, Mohammad Reza Vakili, Amir Hasan Soleimani, Seyed Amirhossein Tabatabaei Dakhili, Sirazum Munira, Marco Paladino, Gary Martin, Frank R. Jirik, Dennis G. Hall, Michael Weinfeld, Afsaneh Lavasanifar
Publikováno v:
Molecular Pharmaceutics. 19:1825-1838
The disruption of polynucleotide kinase/phosphatase (PNKP) in colorectal cancer (CRC) cells deficient in phosphatase and tensin homolog (PTEN) is expected to lead to the loss of cell viability by a process known as synthetic lethality. In previous st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::364d88bcce1bb4dc8cde5d7a629c3695
https://doi.org/10.1021/acs.molpharmaceut.1c00918
https://doi.org/10.1021/acs.molpharmaceut.1c00918
Autor:
Mohamad Estaitie, Dennis G. Hall
Publikováno v:
Chemical Communications. 58:1370-1373
The palladium-catalyzed cross-coupling of an optically enriched dehydropiperidinyl boronate with cinnamyl carbonates was optimized to minimize stereochemical erosion. Although the coupling of two unsymmetrical allyl fragments may generate four possib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5c593e57dafd74e53cf2972a3fd4b44
https://doi.org/10.1039/d1cc06186k
https://doi.org/10.1039/d1cc06186k
Publikováno v:
European Journal of Organic Chemistry. 2022
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90f4120607bbab9b667630db707179c9
https://doi.org/10.1002/ejoc.202201050
https://doi.org/10.1002/ejoc.202201050
Publikováno v:
ACS Catalysis. 11:8902-8914
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53f6ca2b74cf264dc4281986963d5da3
https://doi.org/10.1021/acscatal.1c02172
https://doi.org/10.1021/acscatal.1c02172
Autor:
Dennis G. Hall, M. Zain H. Kazmi, Matthew A. Johnson, Jason P. G. Rygus, Michael J. Ferguson, Marco Paladino, Hwee Ting Ang
Publikováno v:
Journal of the American Chemical Society. 143:10143-10156
Boron-containing heterocycles are important in a variety of applications from drug discovery to materials science; therefore a clear understanding of their structure and reactivity is desirable to optimize these functions. Although the boranol (B-OH)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64c30d74237565f1895e760026e4b579
https://doi.org/10.1021/jacs.1c02462
https://doi.org/10.1021/jacs.1c02462
Autor:
Di Wu, Yangjun Chen, Wenda Wang, Diana Diaz-Dussan, Kazuhiko Ishihara, Ravin Narain, Anika Benozir Asha, Yi-Yang Peng, Dennis G. Hall
Publikováno v:
ACS macro letters. 7(8)
Boronic ester, one typical example of dynamic covalent bonds, has presented great potential to prepare self-healing hydrogels. However, most of currently reported hydrogels based on boronic esters are formed at pH > 8, which impeded their further use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53a783703dc80861aa4c07e9c14f9cb3
https://pubmed.ncbi.nlm.nih.gov/35650963
https://pubmed.ncbi.nlm.nih.gov/35650963