Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Dennis G. Cvitkovitch"'
Autor:
Bo Huang, Cameron A. Stewart, Christopher A. McCulloch, J. Paul Santerre, Dennis G. Cvitkovitch, Yoav Finer
Publikováno v:
Dentistry Journal, Vol 10, Iss 12, p 223 (2022)
Here, we explored the role of S. mutans’s whole cell and discrete fractions in the degradation of type I collagen and dentinal collagen. Type I collagen gels and human demineralized dentin slabs (DS) were incubated in media alone or with one of the
Externí odkaz:
https://doaj.org/article/723ebf8209e94b53937deb1a287f777f
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
We revisited the mathematical model of the chemostat and examined consequences of considerably decreasing the concentration of limiting nutrient in the inflow for the growth of both the planktonic and biofilm cells in the chemostat tank (fermenter).
Externí odkaz:
https://doaj.org/article/1b439261e90f445ca713336c550ae5d0
Autor:
Iwona B. Wenderska, Andrew Latos, Benjamin Pruitt, Sara Palmer, Grace Spatafora, Dilani B. Senadheera, Dennis G. Cvitkovitch
Publikováno v:
mSystems, Vol 2, Iss 1 (2017)
ABSTRACT In the cariogenic Streptococcus mutans, competence development is regulated by the ComRS signaling system comprised of the ComR regulator and the ComS prepeptide to the competence signaling peptide XIP (ComX-inducing peptide). Aside from com
Externí odkaz:
https://doaj.org/article/23e1c7c0695146cdb0914218a4aab703
Dissecting the Role of VicK Phosphatase in Aggregation and Biofilm Formation of Streptococcus mutans
Autor:
Jennifer S. Downey, Xian Peng, Youping Li, Steven D. Goodman, T Tao, Y Qiu, Xuedong Zhou, X Yang, D B Senadheera, Dennis G. Cvitkovitch, L Long, Aidong Han, Suping Wang
Publikováno v:
Journal of Dental Research. 100:631-638
VicRK (WalRK or YycFG) is a conserved 2-component regulatory system (TCS) that regulates cell division, cell wall biosynthesis, and homeostasis in low-GC Gram-positive bacteria. VicRK is also associated with biofilm formation of Streptococcus mutans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a093a65bd47b5758ca9cb57037b31aad
https://doi.org/10.1177/0022034520979798
https://doi.org/10.1177/0022034520979798
Autor:
Eduardo Ayala, Jennifer S Downey, Lauren Mashburn-Warren, Dilani B Senadheera, Dennis G Cvitkovitch, Steven D Goodman
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e108027 (2014)
Two-component systems (TCSs) are ubiquitous among bacteria and are among the most elegant and effective sensing systems in nature. They allow for efficient adaptive responses to rapidly changing environmental conditions. In this study, we investigate
Externí odkaz:
https://doaj.org/article/5e16dd152ea54d518a719a17d84f6e40
Publikováno v:
Acta Biomaterialia. 71:330-338
To identify and characterize specific esterases from S. mutans with degradative activity toward methacrylate-based resin monomers.Out of several putative esterases, an esterase encoded in an Open Reading Frame as SMU_118c (The National Center for Bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afd99eddc2d09b4f93e45c8749eaa1d9
https://doi.org/10.1016/j.actbio.2018.02.020
https://doi.org/10.1016/j.actbio.2018.02.020
Autor:
Dennis G. Cvitkovitch, Natalia Beloglazova, Kemin Tan, Xiaohui Xu, Hong Cui, M. Anca Serbanescu, Alexander F. Yakunin, Milosz Ruszkowski, Alexei Savchenko, Anna N. Khusnutdinova, Sofia Lemak, Greg Brown, Andrzej Joachimiak
Publikováno v:
The Journal of Biological Chemistry
The cariogenic pathogen Streptococcus mutans contains two CRISPR systems (type I-C and type II-A) with the Cas5c protein (SmuCas5c) involved in processing of long CRISPR RNA transcripts (pre-crRNA) containing repeats and spacers to mature crRNA guide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24e6b529bdd078d2617bf4b91c49fdd4
https://doi.org/10.1016/j.jbc.2021.101251
https://doi.org/10.1016/j.jbc.2021.101251
Autor:
L. Jeannine Brady, Paula J. Crowley, Iwona B. Wenderska, Dennis G. Cvitkovitch, Gursonika Binepal, Dilani B. Senadheera, Richard N. Besingi
Publikováno v:
Microbiology. 163:719-730
Potassium (K(+)) is the most abundant cation in dental plaque fluid. Previously, we reported the link between K(+) transport via Trk2 in Streptococcus mutans and its two critical virulence attributes: acid tolerance and surface adhesion. Herein, we b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b4e00d53398a86ad590753a076be68f
https://doi.org/10.1099/mic.0.000458
https://doi.org/10.1099/mic.0.000458
Autor:
Dennis G. Cvitkovitch, Dilani B. Senadheera, Richard N. Besingi, L. Jeannine Brady, Zezhang T. Wen, Joanna R. Long, Iwona B. Wenderska
Publikováno v:
Microbiology. 163:488-501
Amyloids have been identified as functional components of the extracellular matrix of bacterial biofilms. Streptococcus mutans is an established aetiologic agent of dental caries and a biofilm dweller. In addition to the previously identified amyloid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24623d5752d0a3ddee2eb155a712dc15
https://doi.org/10.1099/mic.0.000443
https://doi.org/10.1099/mic.0.000443
Autor:
Yoav Finer, Justin Merritt, Dennis G. Cvitkovitch, Walter L. Siqueira, J. Paul Santerre, Lida Sadeghinejad
Publikováno v:
Dental Materials. 33:175-190
Objectives Investigate the effects of a Bis-phenyl-glycidyl-dimethacrylate (BisGMA) biodegradation product, bishydroxypropoxyphenyl-propane (BisHPPP), on gene expression and protein synthesis of cariogenic bacteria. Methods Quantitative real-time pol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92a8904668ef472bdaa5886f6abf236b
https://doi.org/10.1016/j.dental.2016.11.007
https://doi.org/10.1016/j.dental.2016.11.007