Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Dennis G Cvitkovitch"'
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0165760 (2016)
Triethylene glycol dimethacrylate (TEGDMA) is a diluent monomer used pervasively in dental composite resins. Through hydrolytic degradation of the composites in the oral cavity it yields a hydrophilic biodegradation product, triethylene glycol (TEG),
Externí odkaz:
https://doaj.org/article/6c4cdc48b26f43ffaf8292bdf4d836b7
Autor:
Jennifer S Downey, Lauren Mashburn-Warren, Eduardo A Ayala, Dilani B Senadheera, Whitney K Hendrickson, Lathan W McCall, Julie G Sweet, Dennis G Cvitkovitch, Grace A Spatafora, Steven D Goodman
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e115975 (2014)
Streptococcus mutans, a major acidogenic component of the dental plaque biofilm, has a key role in caries etiology. Previously, we demonstrated that the VicRK two-component signal transduction system modulates biofilm formation, oxidative stress and
Externí odkaz:
https://doaj.org/article/074321a61e3e469db39631097996633a
Autor:
Eduardo Ayala, Jennifer S Downey, Lauren Mashburn-Warren, Dilani B Senadheera, Dennis G Cvitkovitch, Steven D Goodman
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e108027 (2014)
Two-component systems (TCSs) are ubiquitous among bacteria and are among the most elegant and effective sensing systems in nature. They allow for efficient adaptive responses to rapidly changing environmental conditions. In this study, we investigate
Externí odkaz:
https://doaj.org/article/5e16dd152ea54d518a719a17d84f6e40
Autor:
Chen Wang, Jiayan Sang, Jiawei Wang, Mingyan Su, Jennifer S Downey, Qinggan Wu, Shida Wang, Yongfei Cai, Xiaozheng Xu, Jun Wu, Dilani B Senadheera, Dennis G Cvitkovitch, Lin Chen, Steven D Goodman, Aidong Han
Publikováno v:
PLoS Biology, Vol 11, Iss 2, p e1001493 (2013)
Two-component systems (TCSs) are important for the adaptation and survival of bacteria and fungi under stress conditions. A TCS is often composed of a membrane-bound sensor histidine kinase (SK) and a response regulator (RR), which are relayed throug
Externí odkaz:
https://doaj.org/article/2209811eb85f41de96bc1fa2ffe496cb
Autor:
Åsa Nylander, Gunnel Svensäter, Dilani B Senadheera, Dennis G Cvitkovitch, Julia R Davies, Karina Persson
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63768 (2013)
The commensal Streptococcus gordonii expresses numerous surface adhesins with which it interacts with other microorganisms, host cells and salivary proteins to initiate dental plaque formation. However, this Gram-positive bacterium can also spread to
Externí odkaz:
https://doaj.org/article/e0b78bd19c5c4b4d855c8ee6bd8ee93c
Dissecting the Role of VicK Phosphatase in Aggregation and Biofilm Formation of Streptococcus mutans
Autor:
Jennifer S. Downey, Xian Peng, Youping Li, Steven D. Goodman, T Tao, Y Qiu, Xuedong Zhou, X Yang, D B Senadheera, Dennis G. Cvitkovitch, L Long, Aidong Han, Suping Wang
Publikováno v:
Journal of Dental Research. 100:631-638
VicRK (WalRK or YycFG) is a conserved 2-component regulatory system (TCS) that regulates cell division, cell wall biosynthesis, and homeostasis in low-GC Gram-positive bacteria. VicRK is also associated with biofilm formation of Streptococcus mutans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a093a65bd47b5758ca9cb57037b31aad
https://doi.org/10.1177/0022034520979798
https://doi.org/10.1177/0022034520979798
Publikováno v:
Acta Biomaterialia. 71:330-338
To identify and characterize specific esterases from S. mutans with degradative activity toward methacrylate-based resin monomers.Out of several putative esterases, an esterase encoded in an Open Reading Frame as SMU_118c (The National Center for Bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afd99eddc2d09b4f93e45c8749eaa1d9
https://doi.org/10.1016/j.actbio.2018.02.020
https://doi.org/10.1016/j.actbio.2018.02.020
Autor:
Dennis G. Cvitkovitch, Natalia Beloglazova, Kemin Tan, Xiaohui Xu, Hong Cui, M. Anca Serbanescu, Alexander F. Yakunin, Milosz Ruszkowski, Alexei Savchenko, Anna N. Khusnutdinova, Sofia Lemak, Greg Brown, Andrzej Joachimiak
Publikováno v:
The Journal of Biological Chemistry
The cariogenic pathogen Streptococcus mutans contains two CRISPR systems (type I-C and type II-A) with the Cas5c protein (SmuCas5c) involved in processing of long CRISPR RNA transcripts (pre-crRNA) containing repeats and spacers to mature crRNA guide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24e6b529bdd078d2617bf4b91c49fdd4
https://doi.org/10.1016/j.jbc.2021.101251
https://doi.org/10.1016/j.jbc.2021.101251
Autor:
L. Jeannine Brady, Paula J. Crowley, Iwona B. Wenderska, Dennis G. Cvitkovitch, Gursonika Binepal, Dilani B. Senadheera, Richard N. Besingi
Publikováno v:
Microbiology. 163:719-730
Potassium (K(+)) is the most abundant cation in dental plaque fluid. Previously, we reported the link between K(+) transport via Trk2 in Streptococcus mutans and its two critical virulence attributes: acid tolerance and surface adhesion. Herein, we b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b4e00d53398a86ad590753a076be68f
https://doi.org/10.1099/mic.0.000458
https://doi.org/10.1099/mic.0.000458
Autor:
Dennis G. Cvitkovitch, Dilani B. Senadheera, Richard N. Besingi, L. Jeannine Brady, Zezhang T. Wen, Joanna R. Long, Iwona B. Wenderska
Publikováno v:
Microbiology. 163:488-501
Amyloids have been identified as functional components of the extracellular matrix of bacterial biofilms. Streptococcus mutans is an established aetiologic agent of dental caries and a biofilm dweller. In addition to the previously identified amyloid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24623d5752d0a3ddee2eb155a712dc15
https://doi.org/10.1099/mic.0.000443
https://doi.org/10.1099/mic.0.000443