Zobrazeno 1 - 10
of 142
pro vyhledávání: '"Dennis G Cvitkovitch"'
Autor:
Bo Huang, Cameron A. Stewart, Christopher A. McCulloch, J. Paul Santerre, Dennis G. Cvitkovitch, Yoav Finer
Publikováno v:
Dentistry Journal, Vol 10, Iss 12, p 223 (2022)
Here, we explored the role of S. mutans’s whole cell and discrete fractions in the degradation of type I collagen and dentinal collagen. Type I collagen gels and human demineralized dentin slabs (DS) were incubated in media alone or with one of the
Externí odkaz:
https://doaj.org/article/723ebf8209e94b53937deb1a287f777f
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
We revisited the mathematical model of the chemostat and examined consequences of considerably decreasing the concentration of limiting nutrient in the inflow for the growth of both the planktonic and biofilm cells in the chemostat tank (fermenter).
Externí odkaz:
https://doaj.org/article/1b439261e90f445ca713336c550ae5d0
Autor:
Iwona B. Wenderska, Andrew Latos, Benjamin Pruitt, Sara Palmer, Grace Spatafora, Dilani B. Senadheera, Dennis G. Cvitkovitch
Publikováno v:
mSystems, Vol 2, Iss 1 (2017)
ABSTRACT In the cariogenic Streptococcus mutans, competence development is regulated by the ComRS signaling system comprised of the ComR regulator and the ComS prepeptide to the competence signaling peptide XIP (ComX-inducing peptide). Aside from com
Externí odkaz:
https://doaj.org/article/23e1c7c0695146cdb0914218a4aab703
Dissecting the Role of VicK Phosphatase in Aggregation and Biofilm Formation of Streptococcus mutans
Autor:
Jennifer S. Downey, Xian Peng, Youping Li, Steven D. Goodman, T Tao, Y Qiu, Xuedong Zhou, X Yang, D B Senadheera, Dennis G. Cvitkovitch, L Long, Aidong Han, Suping Wang
Publikováno v:
Journal of Dental Research. 100:631-638
VicRK (WalRK or YycFG) is a conserved 2-component regulatory system (TCS) that regulates cell division, cell wall biosynthesis, and homeostasis in low-GC Gram-positive bacteria. VicRK is also associated with biofilm formation of Streptococcus mutans
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0165760 (2016)
Triethylene glycol dimethacrylate (TEGDMA) is a diluent monomer used pervasively in dental composite resins. Through hydrolytic degradation of the composites in the oral cavity it yields a hydrophilic biodegradation product, triethylene glycol (TEG),
Externí odkaz:
https://doaj.org/article/6c4cdc48b26f43ffaf8292bdf4d836b7
Autor:
Jennifer S Downey, Lauren Mashburn-Warren, Eduardo A Ayala, Dilani B Senadheera, Whitney K Hendrickson, Lathan W McCall, Julie G Sweet, Dennis G Cvitkovitch, Grace A Spatafora, Steven D Goodman
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e115975 (2014)
Streptococcus mutans, a major acidogenic component of the dental plaque biofilm, has a key role in caries etiology. Previously, we demonstrated that the VicRK two-component signal transduction system modulates biofilm formation, oxidative stress and
Externí odkaz:
https://doaj.org/article/074321a61e3e469db39631097996633a
Autor:
Eduardo Ayala, Jennifer S Downey, Lauren Mashburn-Warren, Dilani B Senadheera, Dennis G Cvitkovitch, Steven D Goodman
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e108027 (2014)
Two-component systems (TCSs) are ubiquitous among bacteria and are among the most elegant and effective sensing systems in nature. They allow for efficient adaptive responses to rapidly changing environmental conditions. In this study, we investigate
Externí odkaz:
https://doaj.org/article/5e16dd152ea54d518a719a17d84f6e40
Autor:
Chen Wang, Jiayan Sang, Jiawei Wang, Mingyan Su, Jennifer S Downey, Qinggan Wu, Shida Wang, Yongfei Cai, Xiaozheng Xu, Jun Wu, Dilani B Senadheera, Dennis G Cvitkovitch, Lin Chen, Steven D Goodman, Aidong Han
Publikováno v:
PLoS Biology, Vol 11, Iss 2, p e1001493 (2013)
Two-component systems (TCSs) are important for the adaptation and survival of bacteria and fungi under stress conditions. A TCS is often composed of a membrane-bound sensor histidine kinase (SK) and a response regulator (RR), which are relayed throug
Externí odkaz:
https://doaj.org/article/2209811eb85f41de96bc1fa2ffe496cb
Autor:
Åsa Nylander, Gunnel Svensäter, Dilani B Senadheera, Dennis G Cvitkovitch, Julia R Davies, Karina Persson
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63768 (2013)
The commensal Streptococcus gordonii expresses numerous surface adhesins with which it interacts with other microorganisms, host cells and salivary proteins to initiate dental plaque formation. However, this Gram-positive bacterium can also spread to
Externí odkaz:
https://doaj.org/article/e0b78bd19c5c4b4d855c8ee6bd8ee93c
Publikováno v:
Acta Biomaterialia. 71:330-338
To identify and characterize specific esterases from S. mutans with degradative activity toward methacrylate-based resin monomers.Out of several putative esterases, an esterase encoded in an Open Reading Frame as SMU_118c (The National Center for Bio