Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Dennis Feigenbutz"'
Autor:
Irene Riera-Tur, Tillman Schäfer, Daniel Hornburg, Archana Mishra, Lorena Fernández-Mosquera, Dennis Feigenbutz, Patrick Auer, Matthias Mann, Wolfgang Baumeister, Rüdiger Klein, Felix Meissner, Nuno Raimundo, Rubén Fernández-Busnadiego, Irina Dudanova
The autophagy-lysosomal pathway is impaired in many neurodegenerative diseases characterized by protein aggregation, but the link between aggregation and lysosomal dysfunction remains poorly understood. Here, we combine cryo-electron tomography, prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28057a04878dbfcc68220197fa11b70a
Autor:
Irene Riera-Tur, Tillman Schäfer, Daniel Hornburg, Archana Mishra, Miguel da Silva Padilha, Lorena Fernández-Mosquera, Dennis Feigenbutz, Patrick Auer, Matthias Mann, Wolfgang Baumeister, Rüdiger Klein, Felix Meissner, Nuno Raimundo, Rubén Fernández-Busnadiego, Irina Dudanova
Publikováno v:
Life Science Alliance
Life science alliance
Life science alliance
Using cryo-ET, cell biology, and proteomics, this study shows that aggregating proteins impair the autophagy-lysosomal pathway in neurons by sequestering a subunit of the AP-3 adaptor complex.
The autophagy-lysosomal pathway is impaired in many
The autophagy-lysosomal pathway is impaired in many
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2578d3a87b1b6623b6b8bea29af7bee4
https://doi.org/10.26508/lsa.202101185
https://doi.org/10.26508/lsa.202101185
Autor:
Johanna J. Salomon, Dominik Leitz, Ina Lisewski, Pamela Millar-Büchner, Marcus A. Mall, Lisa Korsch, Katrin Schrimpf, Stephan Frings, Anne Hahn, Frank Möhrlen, Dennis Feigenbutz
Publikováno v:
Pflugers Archiv : European journal of physiology. 470(9)
Physiological processes of vital importance are often safeguarded by compensatory systems that substitute for primary processes in case these are damaged by gene mutation. Ca2+-dependent Cl- secretion in airway epithelial cells may provide such a com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d553fa97bd71105f42ac30342de6c3a
https://pubmed.ncbi.nlm.nih.gov/29860639
https://pubmed.ncbi.nlm.nih.gov/29860639