Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Dennis Eng Kiat Tan"'
Autor:
Jieqiong Zhang, Zhenhua Hu, Hwa Hwa Chung, Yun Tian, Kah Weng Lau, Zheng Ser, Yan Ting Lim, Radoslaw M. Sobota, Hwei Fen Leong, Benjamin Jieming Chen, Clarisse Jingyi Yeo, Shawn Ying Xuan Tan, Jian Kang, Dennis Eng Kiat Tan, Ieng Fong Sou, Urszula Lucja McClurg, Manikandan Lakshmanan, Thamil Selvan Vaiyapuri, Anandhkumar Raju, Esther Sook Miin Wong, Vinay Tergaonkar, Ravisankar Rajarethinam, Elina Pathak, Wai Leong Tam, Ern Yu Tan, Wee-Wei Tee
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract Cancer cells undergo transcriptional reprogramming to drive tumor progression and metastasis. Using cancer cell lines and patient-derived tumor organoids, we demonstrate that loss of the negative elongation factor (NELF) complex inhibits bre
Externí odkaz:
https://doaj.org/article/cb2e731233234766a276c66996f09b7a
Publikováno v:
Stem Cells International, Vol 2021 (2021)
Transposable elements (TEs) are mobile genetic sequences capable of duplicating and reintegrating at new regions within the genome. A growing body of evidence has demonstrated that these elements play important roles in host genome evolution, despite
Externí odkaz:
https://doaj.org/article/f2f2fb5a09064aa1beb1b9e4104b6ed5
Autor:
Zhenhua, Hu, Dennis Eng Kiat, Tan, Gloryn, Chia, Haihan, Tan, Hwei Fen, Leong, Benjamin Jieming, Chen, Mei Sheng, Lau, Kelly Yu Sing, Tan, Xuezhi, Bi, Dongxiao, Yang, Ying Swan, Ho, Baojiang, Wu, Siqin, Bao, Esther Sook Miin, Wong, Wee-Wei, Tee
Publikováno v:
Nature cell biology. 22(2)
Mouse embryonic stem cells (ESCs) sporadically transit into an early embryonic-like state characterized by the expression of 2-cell (2C) stage-restricted transcripts. Here, we identify a maternal factor-negative elongation factor A (NELFA)-whose hete