Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Dennis Dlugos"'
Autor:
Karen L. Oliver, Ingrid E. Scheffer, Colin A. Ellis, Bronwyn E. Grinton, Samuel F. Berkovic, Melanie Bahlo, Zaid Afawi, Dina Amrom, Eva Andermann, Jocelyn F. Bautista, Susannah T. Bellows, Judith Bluvstein, Gregory D. Cascino, Seo-Kyung Chung, Patrick Cossette, Sarah W. Curtis, Norman Delanty, Orrin Devinsky, Dennis Dlugos, Michael P. Epstein, Catharine Freyer, Micheline Gravel, Rebekah V. Harris, Erin L. Heinzen, Olivia J. Henry, Heidi E. Kirsch, Robert C. Knowlton, Eric H. Kossoff, Rebecca Loeb, Daniel H. Lowenstein, Anthony G. Marson, Heather C. Mefford, Paul V. Motika, Terence J. O'Brien, Ruth Ottman, Juliann M. Paolicchi, Slave Petrovski, William O. Pickrell, Mark I. Rees, Lynette G. Sadleir, Jerry J. Shih, Rani K. Singh, Michael C. Smith, Philip E.M. Smith, Rhys H. Thomas, Judith Weisenberg, Peter Widdess-Walsh, Melodie R. Winawer
Publikováno v:
EBioMedicine, Vol 109, Iss , Pp 105404- (2024)
Summary: Background: Phenotypic variability within families with epilepsy is often observed, even when relatives share the same monogenic cause. We aimed to investigate whether common polygenic risk for epilepsy could explain the penetrance and pheno
Externí odkaz:
https://doaj.org/article/0d0f5424442d4240b5c116f34ead7cf1
Autor:
Ali Bozorg, Cynthia Beller, Lori Jensen, Alexis Arzimanoglou, Catherine Chiron, Dennis Dlugos, John Gaitanis, James W. Wheless, Carrie McClung
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 3, Pp 780-790 (2024)
Abstract Objective Double‐blind, randomized, and placebo‐controlled trial SP0967 (NCT02477839/2013‐000717‐20) did not demonstrate superior efficacy of lacosamide versus placebo in patients aged ≥1 month to
Externí odkaz:
https://doaj.org/article/b9a085d8f7b942f8a2b7d5e5449e24d8
Autor:
Ian Miller, James W. Wheless, Robert E. Hogan, Dennis Dlugos, Victor Biton, Gregory D. Cascino, Michael R. Sperling, Kore Liow, Blanca Vazquez, Eric B. Segal, Daniel Tarquinio, Weldon Mauney, Jay Desai, Adrian L. Rabinowicz, Enrique Carrazana, The DIAZ.001.05 Study Group
Publikováno v:
Epilepsia Open, Vol 6, Iss 3, Pp 504-512 (2021)
Abstract Objective Need for rescue therapy differs among patients with seizure clusters. Diazepam nasal spray is approved to treat seizure clusters in patients with epilepsy ≥6 years of age. This analysis used interim data from a phase 3 safety stu
Externí odkaz:
https://doaj.org/article/cd72a2846f604d9c895a6114cbca2215
Autor:
Karen Blackmon, Randall Waechter, Barbara Landon, Trevor Noël, Calum Macpherson, Tyhiesia Donald, Nikita Cudjoe, Roberta Evans, Kemi S Burgen, Piumi Jayatilake, Vivian Oyegunle, Otto Pedraza, Samah Abdel Baki, Thomas Thesen, Dennis Dlugos, Geetha Chari, Archana A Patel, Elysse N Grossi-Soyster, Amy R Krystosik, A Desiree LaBeaud
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 11, p e0008874 (2020)
Children with Congenital Zika Syndrome and microcephaly are at high risk for epilepsy; however, the risk is unclear in normocephalic children with prenatal Zika virus (ZIKV) exposure [Exposed Children (EC)]. In this prospective cohort study, we perfo
Externí odkaz:
https://doaj.org/article/bd0a960094df4885b3d35bd3e5d4f1f5
Autor:
Piumi Jayatilake, Vivian Oyegunle, Randall Waechter, Barbara Landon, Michelle Fernandes, Nikita Cudjoe, Roberta Evans, Trevor Noël, Calum Macpherson, Tyhiesia Donald, Samah G. Abdelbaki, Kesava Mandalaneni, Dennis Dlugos, Geetha Chari, Archana A. Patel, Elysse N. Grossi-Soyster, A. Desiree LaBeaud, Karen Blackmon
Publikováno v:
Epilepsy & Behavior Reports, Vol 14, Iss , Pp 100411- (2020)
Zika virus (ZIKV) is a mosquito-borne, single-stranded DNA flavivirus that is teratogenic and neurotropic. Similar to the teratogenic effects of other TORCH infections, ZIKV infection during pregnancy can have an adverse impact on fetal and neonatal
Externí odkaz:
https://doaj.org/article/7416ec9c51be4495b8422130e315ca66
Autor:
Jacqueline A. French, Elena Cleary, Dennis Dlugos, Gail Farfel, Kathleen Farrell, Barry Gidal, Caitlin L. Grzeskowiak, Rachel Gurrell, Cynthia Harden, Tracy J. Stalvey, Julia Tsai, Elaine C. Wirrell, David Blum, Nathan Fountain
Publikováno v:
Epilepsia. 63:2664-2670
Drug treatment for children with epilepsy should, ideally, be governed by evidence from adequate and well-controlled clinical studies. However, these studies are difficult to conduct, and so direct evidence supporting the informed use of specific dru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::459eca2cf7adb51471429476cf52ba5d
https://doi.org/10.1111/epi.17366
https://doi.org/10.1111/epi.17366
Autor:
Daniel Tarquinio, Dennis Dlugos, James W. Wheless, Jay Desai, Enrique Carrazana, Adrian L. Rabinowicz
Publikováno v:
Pediatric Neurology. 132:50-55
To evaluate safety and tolerability of long-term treatment with diazepam nasal spray (Valtoco) for seizure clusters in patients aged six to 17 years.The study enrolled patients aged six to 65 years with frequent seizure clusters. Age- and weight-base
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bd6eaad3ff8b501874d05083eafd5b0
https://doi.org/10.1016/j.pediatrneurol.2022.04.011
https://doi.org/10.1016/j.pediatrneurol.2022.04.011
Autor:
Venkatesha Murthy, Dennis Dlugos, Yasir Khan, Samuel Hsiao, Arturo Benitez, Mahnaz Asgharnejad
Publikováno v:
Wednesday, April 26.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d94989ae8fa98e3a56c222a7c9be5b43
https://doi.org/10.1212/wnl.0000000000203534
https://doi.org/10.1212/wnl.0000000000203534
Publikováno v:
Thursday, April 27.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0efc0308aa258503781097f7ae2018b6
https://doi.org/10.1212/wnl.0000000000202980
https://doi.org/10.1212/wnl.0000000000202980
Autor:
Michael R, Sperling, James W, Wheless, R Edward, Hogan, Dennis, Dlugos, Gregory D, Cascino, Kore, Liow, Adrian L, Rabinowicz, Enrique, Carrazana
Publikováno v:
Epilepsia. 63:836-843
An exploratory analysis from a long-term, phase 3, open-label, repeat-dose safety study of diazepam nasal spray for acute treatment of seizure clusters assessed the use of a second dose up to 24 hours after the initial dose and effectiveness in poten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c6edecfb3dfa1c1cc62e470d4d50a69
https://doi.org/10.1111/epi.17177
https://doi.org/10.1111/epi.17177