Výsledky vyhledávání - "Dennis D Taub"

Akademický článek

Lipid-Laden Multilocular Cells in the Aging Thymus Are Phenotypically Heterogeneous.

Autor: Larissa G P Langhi, Leonardo R Andrade, Marilia Kimie Shimabukuro, Willem van Ewijk, Dennis D Taub, Radovan Borojevic, Valeria de Mello Coelho

Publikováno v: PLoS ONE, Vol 10, Iss 10, p e0141516 (2015)

Intrathymic lipid-laden multilocular cells (LLMC) are known to express pro-inflammatory factors that might regulate functional activity of the thymus. However, the phenotype of age-associated intrathymic LLMC is still controversial. In this study, we

Externí odkaz: https://doaj.org/article/4313fc4ebc7142328472dbe3d8b1283b

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Akademický článek

The severity of experimental autoimmune cystitis can be ameliorated by anti-CXCL10 Ab treatment.

Autor: Udai P Singh, Narendra P Singh, Honbing Guan, Venkatesh L Hegde, Robert L Price, Dennis D Taub, Manoj K Mishra, Mitzi Nagarkatti, Prakash S Nagarkatti

Publikováno v: PLoS ONE, Vol 8, Iss 11, p e79751 (2013)

BackgroundInterstitial cystitis (IC), more recently called painful bladder syndrome (PBS) is a complex disease associated with chronic bladder inflammation that primarily affects women. Its symptoms include frequent urinary urgency accompanied by dis

Externí odkaz: https://doaj.org/article/6e0f13179494455bbc0cb2a00a7810ca

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Akademický článek

A genome-wide association scan on the levels of markers of inflammation in Sardinians reveals associations that underpin its complex regulation.

Publikováno v: PLoS Genetics, Vol 8, Iss 1, p e1002480 (2012)

Identifying the genes that influence levels of pro-inflammatory molecules can help to elucidate the mechanisms underlying this process. We first conducted a two-stage genome-wide association scan (GWAS) for the key inflammatory biomarkers Interleukin

Externí odkaz: https://doaj.org/article/c4706c9af750415bb33bf522097b1205

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Akademický článek

Ceruloplasmin deficiency reduces levels of iron and BDNF in the cortex and striatum of young mice and increases their vulnerability to stroke.

Autor: Sarah J Texel, Jian Zhang, Simonetta Camandola, Erica L Unger, Dennis D Taub, Raymond C Koehler, Z Leah Harris, Mark P Mattson

Publikováno v: PLoS ONE, Vol 6, Iss 9, p e25077 (2011)

Ceruloplasmin (Cp) is an essential ferroxidase that plays important roles in cellular iron trafficking. Previous findings suggest that the proper regulation and subcellular localization of iron are very important in brain cell function and viability.

Externí odkaz: https://doaj.org/article/437b16f2fd614508895b370e41589417

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Akademický článek

Involvement of mTOR in CXCL12 mediated T cell signaling and migration.

Autor: Rachel Munk, Paritosh Ghosh, Manik C Ghosh, Takeshi Saito, Mai Xu, Arnell Carter, Fred Indig, Dennis D Taub, Dan L Longo

Publikováno v: PLoS ONE, Vol 6, Iss 9, p e24667 (2011)

CXCL12 is a pleiotropic chemokine involved in multiple different processes such as immune regulation, inflammatory responses, and cancer development. CXCL12 is also a potent chemokine involved in chemoattraction of T cells to the site of infection or

Externí odkaz: https://doaj.org/article/239eb3a7ec3048d3ad0ac2c79a394c70

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