Zobrazeno 1 - 5
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pro vyhledávání: '"Dennis C. Morse"'
Autor:
Dennis C. Morse
Publikováno v:
Birth Defects Research. Part B, Developmental and Reproductive Toxicology
Pregabalin was evaluated for potential developmental toxicity in mice and rabbits. Pregabalin was administered once daily by oral gavage to female albino mice (500, 1250, or 2500 mg/kg) and New Zealand White rabbits (250, 500, or 1250 mg/kg) during o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80a6ff0b9df9d123205db5e170de322e
http://europepmc.org/articles/PMC6585796
http://europepmc.org/articles/PMC6585796
Publikováno v:
Birth Defects Research. Part B, Developmental and Reproductive Toxicology
Pregabalin was administered to pregnant Wistar rats during organogenesis to evaluate potential developmental toxicity. In an embryo-fetal development study, compared with controls, fetuses from pregabalin-treated rats exhibited increased incidence of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6fe75690f4bca69c75008c7912f18f6
http://europepmc.org/articles/PMC6585975
http://europepmc.org/articles/PMC6585975
Autor:
Sharon A. Sokolowski, Steven Duddy, Kay A. Criswell, Zbigniew Wojcinski, Michael T. Lawton, Joseph T. Brady, Christopher Somps, Ramin Rahbari, Dennis C. Morse, Marc D. Roy, Jennifer Colangelo, Leslie A. Obert, Jon C. Cook, David G. Pegg, Petra H. Koza-Taylor, Timothy Anderson, Kimberly A. Navetta
Publikováno v:
Toxicological Sciences. 128:42-56
The preceding article identified key components of pregabalin's mode of action on nongenotoxic hemangiosarcoma formation in mice, including increased serum bicarbonate leading to decreased respiratory rate, increased blood pH, increased venous oxygen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af0df5126d3a40653d7d787746176f2a
https://doi.org/10.1093/toxsci/kfs148
https://doi.org/10.1093/toxsci/kfs148
Publikováno v:
Toxicology and Applied Pharmacology. 152:232-239
Cytochromes P450 1A1 and 1A2 are involved in the oxidation of a wide spectrum of endogenous compounds and xenobiotics. Although their presence has been repeatedly confirmed in brain tissue, reports regarding their distribution in the brain are often
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b81ee2e0b36ef36d168aa4f92343960e
https://doi.org/10.1006/taap.1998.8477
https://doi.org/10.1006/taap.1998.8477
Autor:
Corine Koopman-Esseboom, Dennis C Morse, Nynke Weisglas-Kuperus, Abraham Brouwer, Pieter J Sauer
Publikováno v:
Pediatric Research. 36:22A-22A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5656e4e1852561a1a814eeffc8a93ad
https://doi.org/10.1203/00006450-199407000-00115
https://doi.org/10.1203/00006450-199407000-00115