Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Dennis C. Lynch"'
Publikováno v:
Blood. 76:2530-2539
von Willebrand factor (vWF) is a multimeric adhesive glycoprotein essential for normal hemostasis. We have discovered that cultured human umbilical vein endothelial cells incorporate inorganic sulfate into vWF. Following immunoisolation and analysis
By transfecting the full-length cDNA for human von Willebrand factor (vWf) into a line of Chinese hamster ovary cells with a defect in carbohydrate metabolism, we have prepared recombinant vWf specifically lacking O-linked carbohydrates. We have comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fc7be2c00ab4efe0650ccfbac9d8663
https://europepmc.org/articles/PMC443377/
https://europepmc.org/articles/PMC443377/
Autor:
Dennis C. Lynch
Publikováno v:
Annals of the New York Academy of Sciences. 614
Autor:
Paul Schimmel, Dennis C. Lynch
Publikováno v:
Biochemistry. 13:1852-1861
Autor:
Theodore S. Zimmerman, Rodney Williams, Edward P. Kirby, Dennis C. Lynch, David M. Livingston
Publikováno v:
Proceedings of the National Academy of Sciences. 80:2738-2742
The biosynthesis of the subunit of factor VIIIR was studied in bovine aortic endothelial cells by the techniques of immunoprecipitation and NaDodSO4/polyacrylamide gel electrophoresis. It was determined that the subunit is first produced as a Mr 240,
Autor:
Richard B. Levene, Jerald P. Underdahl, Dennis C. Lynch, George Ricca, David M. Livingston, Christina P. Ravera, Markar J. Dombalagian, Carolyn J. Collins, Melinda J. Morin
Publikováno v:
Proceedings of the National Academy of Sciences. 84:4393-4397
A series of overlapping cosmid genomic clones have been isolated that contain the entire coding unit of the human gene for von Willebrand factor (vWf), a major component of the hemostatic system. The cloned segments span approximately 175 kilobases o
Publikováno v:
Journal of Biological Chemistry. 258:12757-12760
The oligomerization of human endothelial cell-synthesized von Willebrand factor (vWf) has been studied by gel chromatography in columns of Sephacryl S-500 and by discontinuous agarose gel electrophoresis. A quantitative recovery of high Mr vWf oligom
Publikováno v:
British Journal of Haematology. 64:15-20
Autor:
James A. Koziol, P Ranieri, Dennis C. Lynch, N. Ciavarella, J Gitschier, Zaverio M. Ruggeri, V T Glotz, K Y Ngo, Theodore S. Zimmerman
Publikováno v:
Proceedings of the National Academy of Sciences. 85:2753-2757
Severe von Willebrand disease is characterized by undetectable or trace quantities of von Willebrand factor in plasma and tissue stores. We have studied the genomic DNA of 10 affected individuals from six families with this disorder using probes from
Autor:
Zaverio M. Ruggeri, Dennis C. Lynch, Theodore S. Zimmerman, K Y Ngo, J Gitscher, N Ciavarella
Publikováno v:
XIth International Congress on Thrombosis and Haemostasis.
Severe von Willebrand disease (vWD) is characterized by undetectable levels of von Willebrand factor (vWF), or trace amounts, in plasma and tissue stores. We have studied the genomic DNA of ten affected individuals from five families with this disord