Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Dennis C. Lefebvre"'
Autor:
Brian H. Rowe, Jennifer L. Williams, Mark Yarema, Danielle Blouin, Kathryn Dong, Erica Dance, Rhonda J. Rosychuk, Dennis C. Lefebvre
Publikováno v:
Cureus
Background Recent literature highlights the alarming prevalence of burnout, depression, and illness during residency training; a trend that is also linked to suboptimal patient care. Dedicated wellness curricula may be one solution to this concerning
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bc8907b87bf63b50d253462e66fa6ce
https://doi.org/10.7759/cureus.5314
https://doi.org/10.7759/cureus.5314
Autor:
Dennis C. Lefebvre
Publikováno v:
Academic Medicine. 87:598-602
Residency training is a challenging period in a physician's career owing to a multitude of stressors perhaps not previously encountered. In some cases, these stressors may culminate in a state of burnout. In response, much has been written about the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f41c6204612cc25a84a4b01cff0aad4
https://doi.org/10.1097/acm.0b013e31824d47ff
https://doi.org/10.1097/acm.0b013e31824d47ff
Autor:
Jennifer L. Cross, Dennis C. Lefebvre, Andrea S. L. Wong, Jacqueline C.Y. Lai, Jennifer L. Ford, Nina Maeshima, Pauline Johnson
Publikováno v:
Molecular Immunology. 47:1882-1889
CD44 is a widely expressed cell adhesion molecule with functional similarities to the selectin and integrin adhesion molecules. CD44 has a lectin domain that binds hyaluronan, a component of the extracellular matrix. Interactions between CD44 and hya
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c51cdaaf36224ba91b5ee55605eb9a96
https://doi.org/10.1016/j.molimm.2010.03.018
https://doi.org/10.1016/j.molimm.2010.03.018
Publikováno v:
Clinical Infectious Diseases. 41:S73-S78
The treatment of injection drug users (IDUs) coinfected with human immunodeficiency virus (HIV) and hepatitis C virus (HCV) presents multiple challenges, many of which could be addressed by the development of directly observed therapy programs. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbfea4144fb750407924b4070d2ed0d6
https://doi.org/10.1086/429500
https://doi.org/10.1086/429500
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1650:40-49
The Src-family tyrosine kinase, Lck, contains two key regulatory phosphotyrosine residues, tyrosine 394 (Tyr-394) and tyrosine 505 (Tyr-505), both of which can be dephosphorylated by CD45. Here, the interaction of CD45 with its substrate, Lck, was de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44a4e541861c1fc79f25babc708da57c
https://doi.org/10.1016/s1570-9639(03)00190-0
https://doi.org/10.1016/s1570-9639(03)00190-0
Autor:
Dennis C. Lefebvre
Publikováno v:
Academic medicine : journal of the Association of American Medical Colleges. 88(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a881cd3c2c257498c7fd8e83342651b
https://pubmed.ncbi.nlm.nih.gov/23267219
https://pubmed.ncbi.nlm.nih.gov/23267219
Autor:
Dennis C, Lefebvre
Publikováno v:
CJEM. 13(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b5314bd43e490dfa97bdc2a150a50204
https://pubmed.ncbi.nlm.nih.gov/21524364
https://pubmed.ncbi.nlm.nih.gov/21524364
Autor:
David H.W. Ng, Pauline Johnson, Dennis C. Lefebvre, Jennifer L. Cross, Mindy Cw Lam, Yanni Wang, Jackie Felberg, Darlene Birkenhead
Publikováno v:
The Journal of biological chemistry. 279(5)
CD45 is a transmembrane, two-domain protein-tyrosine phosphatase expressed exclusively in nucleated hematopoietic cells. The Src family kinase, Lck, is a major CD45 substrate in T cells and CD45 dephosphorylation of Lck is important for both T cell d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a5a4ed281836e00a693e01f9c769ff1
https://pubmed.ncbi.nlm.nih.gov/14625311
https://pubmed.ncbi.nlm.nih.gov/14625311
Autor:
Dennis C. Lefebvre
Publikováno v:
CJEM. 13:E12-E13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7169b966928d3a912b6bf129451496e
https://doi.org/10.2310/8000.2011.110463
https://doi.org/10.2310/8000.2011.110463
Autor:
Dennis C. Lefebvre
Publikováno v:
CJEM. 14:133
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::160135e8de687b1f369741c8ce7e63d7
https://doi.org/10.2310/8000.2012.110600
https://doi.org/10.2310/8000.2012.110600