Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Dennis C Chan"'
Autor:
Madison K. Kuhn, Rebecca M. Fleeman, Lynne M. Beidler, Amanda M. Snyder, Dennis C. Chan, Elizabeth A. Proctor
IntroductionNeuroinflammation and metabolic dysfunction are early alterations in Alzheimer’s disease brain that are thought to contribute to disease onset and progression. Glial activation due to protein deposition results in cytokine secretion and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72ac497487bcef2d8ee44d2c942d88e6
https://doi.org/10.1101/2023.04.07.536014
https://doi.org/10.1101/2023.04.07.536014
Autor:
Rebecca M Fleeman, Amanda M Snyder, Madison K Kuhn, Dennis C Chan, Grace C Smith, Nicole A Crowley, Amy C Arnold, Elizabeth A Proctor
Publikováno v:
Neurobiology of aging.
The ε4 variant of apolipoprotein E (APOE) is the strongest and most common genetic risk factor for Alzheimer’s disease (AD). While the mechanism of conveyed risk is incompletely understood, promotion of inflammation, dysregulated metabolism, and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6b2182a1daa304f4a5dc49260d1a416
https://pubmed.ncbi.nlm.nih.gov/36572594
https://pubmed.ncbi.nlm.nih.gov/36572594
Autor:
Christy George, John N. Alumasa, Adam Bolotsky, Michael D. Howe, Anthony D. Baughn, Dennis C. Chan, Andrew W. Simonson, Scott H. Medina, Elizabeth A. Proctor, Tapas K. Mal, Kenneth C. Keiler, Agustey S. Mongia, Atip Lawanprasert, Matthew R. Aronson, Aida Ebrahimi
Publikováno v:
Nature biomedical engineering
Precision antimicrobials aim to kill pathogens without damaging commensal bacteria in the host, and thereby cure disease without antibiotic-associated dysbiosis. Here we report the de novo design of a synthetic host defence peptide that targets a spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29ca644ed7043ad5af37917b7eeef625
http://europepmc.org/articles/PMC8131206
http://europepmc.org/articles/PMC8131206
Autor:
Elizabeth A. Proctor, Agustey S. Mongia, Kenneth C. Keiler, Andrew W. Simonson, Dennis C. Chan, Aida Ebrahimi, Matthew R. Aronson, John N. Alumasa, Adam Bolotsky, Scott H. Medina
Precision antimicrobials that can kill pathogens without damaging host commensals hold potential to cure disease without antibiotic-associated dysbiosis. Here we report the de novo design of host defense peptides that have been rationally engineered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab9764a2c27e9275a2abfacb11be4153
https://doi.org/10.26434/chemrxiv.12267992
https://doi.org/10.26434/chemrxiv.12267992
Publikováno v:
Biomedical Optics Express. 7:5120
Optical mapping (OM) of electrical activity using voltage-sensitive fluorescent dyes is a powerful tool for the investigation of embryonic cardiac electrophysiology. However, because conventional OM integrates the signal in depth and projects it to a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae847c96c26f18db2c5c46f4243d296b
https://doi.org/10.1364/boe.7.005120
https://doi.org/10.1364/boe.7.005120
Autor:
Catriona D. Good, Rachael I. Scahill, Nick C. Fox, John Ashburner, Dennis C. Chan, William R. Crum, Martin N. Rossor, Richard S.J. Frackowiak
Publikováno v:
NeuroImage. 13:317
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f76e92fd92a95e1c079f7d6f80a2bd5
https://doi.org/10.1016/s1053-8119(01)91660-x
https://doi.org/10.1016/s1053-8119(01)91660-x