Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Dennis Bosch"'
Autor:
Wei Zhang, Emanuele Gioacchino, Cansu Koyunlar, Joke Zink, Hans de Looper, Kirsten J. Gussinklo, Remco Hoogenboezem, Dennis Bosch, Eric Bindels, Ivo P. Touw, Emma de Pater
Publikováno v:
HemaSphere, Vol 7, p e94325dc (2023)
Externí odkaz:
https://doaj.org/article/30747f125c114725a39d2c81bfa3fc96
Autor:
Thijs van Bergen, Anna Aalbers, Dennis Bosch, Onno Roovers, Akiko Shimamura, Marc H.G.P. Raaijmakers, Peter E. Newburger, Ivo P Touw
Publikováno v:
Blood. 140:5463-5464
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1db5df91f12f73972a4c5a659608ffe2
https://doi.org/10.1182/blood-2022-165112
https://doi.org/10.1182/blood-2022-165112
Autor:
Emanuele Gioacchino, Wei Zhang, Cansu Koyunlar, Joke Zink, Hans de Looper, Kirsten J. Gussinklo, Remco Hoogenboezem, Dennis Bosch, Eric Bindels, Ivo P. Touw, Emma de Pater
The transcription factor GATA2 has pivotal roles in hematopoiesis. Germline GATA2 mutations in patients result in GATA2 haploinsufficiency syndrome characterized by immunodeficiency, bone marrow failure, and predispositions to myelodysplastic syndrom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49378a3a60c0e865c3f6b9414749af36
https://doi.org/10.1101/2021.10.29.466416
https://doi.org/10.1101/2021.10.29.466416
Autor:
Cansu Koyunlar, Hans de Looper, Dennis Bosch, Rui Monteiro, Emma de Pater, Joke Zink, Ivo P. Touw, Christopher B. Mahony, Madelon de Jong, Martin E. van Royen, Tomasz Dobrzycki, Eric Bindels, Remco Hoogenboezem, Paulina M. H. van Strien, Kirsten Gussinklo, Pim J. French, Emanuele Gioacchino
Publikováno v:
Blood advances, 5(13), 2687-2700. American Society of Hematology
Blood Adv
Blood Adv
The differentiation of hematopoietic stem cells (HSCs) is tightly controlled to ensure a proper balance between myeloid and lymphoid cell output. GATA2 is a pivotal hematopoietic transcription factor required for generation and maintenance of HSCs. G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2392ec675cf9bc0fb3b280f84aed1a82
https://pure.eur.nl/en/publications/24190a85-ae08-4ceb-901f-766bd542a9aa
https://pure.eur.nl/en/publications/24190a85-ae08-4ceb-901f-766bd542a9aa
Autor:
Mehrnaz Ghazvini, Eric M.J. Bindels, Ivo P. Touw, Paulina M. H. van Strien, Vincent H.J. van der Velden, Remco Hoogenboezem, Dennis Bosch, Pier G. Mastroberardino, Emma de Pater, Hans de Looper, Onno Roovers, Sander Barnhoorn, Patricia A. Olofsen
Publikováno v:
Blood Adv
Blood advances, 5(3), 775-786. American Society of Hematology
Blood advances, 5(3), 775-786. American Society of Hematology
Mutations in ELANE cause severe congenital neutropenia (SCN), but how they affect neutrophil production and contribute to leukemia predisposition is unknown. Neutropenia is alleviated by CSF3 (granulocyte colony-stimulating factor) therapy in most ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68f08ea678a32baf8533b2f0251fb3d0
https://pubmed.ncbi.nlm.nih.gov/33560392
https://pubmed.ncbi.nlm.nih.gov/33560392
Autor:
Remco Hoogenboezem, Paulette van Strien, Cansu Koyunlar, Hans de Looper, Madelon de Jong, Pim J. French, Emma de Pater, Joke Peulen, Emanuele Gioacchino, Eric Bindels, Kirsten Gussinklo, Rui Monteiro, Dennis Bosch, Ivo P. Touw, Tomasz Dobrzycki, Martin E. van Royen
Hematopoietic stem cells (HSCs) are tightly controlled to keep a balance between myeloid and lymphoid cell differentiation. Gata2 is a pivotal hematopoietic transcription factor required for HSC generation and maintenance. We generated a zebrafish mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc856faa36e101cf77398dc8347b9b27
https://doi.org/10.1101/753178
https://doi.org/10.1101/753178
Autor:
Remco Hoogenboezem, Ruud Delwel, Paulette van Strien, Ivo P. Touw, Eric Bindels, Dennis Bosch, Emanuele Gioacchino, Joke Peulen, Marije Havermans, Disha Vadgama, Emma de Pater, Cansu Koyunlar, Hans de Looper, Elaine Dzierzak
Publikováno v:
Experimental Hematology. 88:S68
GATA2 is the most frequently mutated gene in childhood AML. These patients have germline mutations in one allele of GATA2 and have a high predisposition for MDS/AML. Also, in mouse, Gata2 is required for embryonic HSC generation and survival and Gata
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f65d52648261b7b4e08df5e0ab9af44
https://doi.org/10.1016/j.exphem.2020.09.111
https://doi.org/10.1016/j.exphem.2020.09.111
Autor:
Ivo P. Touw, E. de Pater, E. Bindels, Ruud Delwel, Marije Havermans, Emanuele Gioacchino, Dennis Bosch, Remco Hoogenboezem, J. Klavert, P. van strien, H. de looper, Elaine Dzierzak, Cansu Koyunlar
Publikováno v:
HemaSphere. 3:385
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5937eea6a2e39c95d3d1e7215ba35e9
https://doi.org/10.1097/01.hs9.0000561728.52101.15
https://doi.org/10.1097/01.hs9.0000561728.52101.15