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pro vyhledávání: '"Dennis Adair"'
Publikováno v:
Drug Development and Industrial Pharmacy. 16:1217-1231
Povidone (PVP)/Polydimethylsiloxane (PDMS) matrices were evaluated as drug delivery devices. PVP was utilized as a hydrophilic component to alter drug release. Salicylic acid was employed as a model drug substance.Discs were prepared by placing the b
Publikováno v:
Journal of Pharmaceutical Sciences. 73:799-803
A system was developed which is capable of monitoring the dissolution profiles of each of the active components in a two-component combination product. The UV spectra of the two drugs (metoprolol and hydro-chlorothiazide) overlap considerably, making
Publikováno v:
Journal of pharmacokinetics and biopharmaceutics. 13(5)
A system is described for developing extended-release products, based upon predicting or simulating the entire plasma level-time curve to be expected from the administration of a controlled-release oral dosage form. Termed "biorelevant dissolution,"
Conference
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