Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Dennis A. Noe"'
Autor:
Majid Y. Moridani
Publikováno v:
Clinical Biochemistry. 35:659-660
Autor:
James C Boyd
Publikováno v:
Clinical Chemistry. 48:1141-1142
Autor:
Dennis A. Noe
Publikováno v:
Pharmaceutical Statistics. 19:101-112
Various criteria have been proposed for determining the reliability of noncompartmental pharmacokinetic estimates of the terminal disposition phase half-life (t1/2 ) and the extrapolated area under the curve (AUCextrap ). This simulation study assess
Autor:
Dennis A. Noe
Publikováno v:
Pharmaceutical Statistics. 19:88-100
The adjusted r2 algorithm is a popular automated method for selecting the start time of the terminal disposition phase (tz ) when conducting a noncompartmental pharmacokinetic data analysis. Using simulated data, the performance of the algorithm was
Autor:
Dennis A. Noe
Publikováno v:
Clinical Pharmacology in Drug Development. 9
The noncompartmental analysis (NCA) of pharmacokinetic (PK) data is important throughout all phases of clinical drug development. Although there are numerous regulatory guidances and articles in the literature concerned with best practices for the mo
Autor:
Dennis A. Noe
Publikováno v:
Clinical pharmacology in drug development. 6(6)
Publikováno v:
Medical Decision Making; February 1987, Vol. 7 Issue: 1 p70-70, 1p
Autor:
Tommy Cedervall, Elizabeth E. Eynon, Xinguo Chen, Sandra L. Wolin, Hong Shi, Derek D. Yang, Dahai Xue, Richard A. Flavell, James D. Smith, Michael Kashgarian, Dennis A. Noe, Douglas E. Brash
Publikováno v:
Proceedings of the National Academy of Sciences. 100:7503-7508
Antibodies against a conserved RNA-binding protein, the Ro 60-kDa autoantigen, occur in 24–60% of all patients with systemic lupus erythematosus. Anti-Ro antibodies are correlated with photosensitivity and cutaneous lesions in these patients and wi
A Phase I and Pharmacologic Study of Pyrazoloacridine and Cisplatin in Patients with Advanced Cancer
Autor:
Kathy Elza-Brown, Eric K. Rowinsky, Ross C. Donehower, Dennis A. Noe, Alex A. Adjei, E. Claire Dees, Seamus O’Reilly
Publikováno v:
Investigational New Drugs. 21:75-84
Pyrazoloacridine (PZA, NSC366140, PD115934) is an acridine derivative currently undergoing clinical evaluation. In preclinical testing, PZA has shown selectivity for solid tumor cell lines, activity in hypoxic, noncycling, and multidrug-resistant cel
Publikováno v:
ResearcherID
The U6 small nuclear ribonucleoprotein is a critical component of the eukaryotic spliceosome. The first protein that binds the U6 snRNA is the La protein, an abundant phosphoprotein that binds the 3′ end of many nascent small RNAs. A complex of sev