Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Dennis A Kutateladze"'
Publikováno v:
Journal of the American Chemical Society. 144:15812-15824
The mechanism of chiral hydrogen-bond donor (HBD) and hydrogen chloride (HCl) co-catalyzed Prins cyclizations was analyzed through a combination of experimental and computational methods and revealed to involve an unexpected and previously unrecogniz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::552809b37285b139c1941a92d65a0f72
https://doi.org/10.1021/jacs.2c06688
https://doi.org/10.1021/jacs.2c06688
Autor:
Dennis A Kutateladze, Hening Lin, Bo Li, Johan Auwerx, Yashira L Negrón Abril, Bin He, Jessica Jingyi Bai, Jun Young Hong, Ying-Ling Chiang, Ravi Dhawan, Fangyu Wang, Qingjie Zhao, Brenna Remick, Robert S. Weiss, Viviana Maymi, Richard A. Cerione, Irma Fernandez, Sushabhan Sadhukhan, Teresa L. Southard, James Mullmann, Min Yang, Jing Hu
Publikováno v:
Oncogene
SIRT5 is a member of the sirtuin family of NAD(+)-dependent protein lysine deacylases implicated in a variety of physiological processes. SIRT5 removes negatively charged malonyl, succinyl, and glutaryl groups from lysine residues and thereby regulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec16c2ad75751dde0aa1e464fae4ab66
https://doi.org/10.1038/s41388-020-01637-w
https://doi.org/10.1038/s41388-020-01637-w
Publikováno v:
J Am Chem Soc
Chiral urea derivatives are shown to catalyze enantioselective tail-to-head cyclization reactions of neryl chloride analogues. Experimental data are consistent with a mechanism in which π-participation by the nucleophilic olefin facilitates chloride
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45fb00bed18e5f259d72fe5e940671b5
https://doi.org/10.1021/jacs.0c02665
https://doi.org/10.1021/jacs.0c02665