Výsledky vyhledávání - "Dennis A, Gastineau"

Akademický článek

Exercise and the immune system: taking steps to improve responses to cancer immunotherapy

Autor: Michael P Gustafson, Dennis A Gastineau, Bruce D Johnson, Richard J Simpson, Courtney M Wheatley-Guy, Allison C Rosenthal, Emmanuel Katsanis

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 9, Iss 7 (2021)

The remarkable success of cancer immunotherapies has provided new hope to cancer patients. Unfortunately, a significant proportion of patients remain unable to respond to immunotherapy or maintain durable clinical responses. The lack of objective res

Externí odkaz: https://doaj.org/article/0049e0d2c2924106a48ae4cba836a50f

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Akademický článek

Comprehensive assessment of circulating immune cell populations in response to stereotactic body radiation therapy in patients with liver cancer

Autor: Michael P. Gustafson, PhD, Svetlana Bornschlegl, BS, Sean S. Park, MD, PhD, Dennis A. Gastineau, MD, Lewis R. Roberts, MB, ChB, PhD, Allan B. Dietz, PhD, Christopher L. Hallemeier, MD

Publikováno v: Advances in Radiation Oncology, Vol 2, Iss 4, Pp 540-547 (2017)

Stereotactic body radiation therapy (SBRT) can positively influence an antitumor immune response by inducing necrotic cell death. SBRT also been shown to eliminate tumors outside the radiation therapy field through an immune-mediated process known as

Externí odkaz: https://doaj.org/article/749f2688ad544dec92507c295afa1acd

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Akademický článek

A systems biology approach to investigating the influence of exercise and fitness on the composition of leukocytes in peripheral blood

Autor: Michael P. Gustafson, Ara Celi DiCostanzo, Courtney M. Wheatley, Chul-Ho Kim, Svetlana Bornschlegl, Dennis A. Gastineau, Bruce D. Johnson, Allan B. Dietz

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 5, Iss 1, Pp 1-14 (2017)

Abstract Background Exercise immunology has become a growing field in the past 20 years, with an emphasis on understanding how different forms of exercise affect immune function. Mechanistic studies are beginning to shed light on how exercise may imp

Externí odkaz: https://doaj.org/article/b45a5d561f944e9091cbcf456ca0c84c

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Akademický článek

The CD14+HLA-DRlo/neg Monocyte: An Immunosuppressive Phenotype That Restrains Responses to Cancer Immunotherapy

Autor: April E. Mengos, Dennis A. Gastineau, Michael P. Gustafson

Publikováno v: Frontiers in Immunology, Vol 10 (2019)

Recent successes in cancer immunotherapy have been tempered by sub-optimal clinical responses in the majority of patients. The impaired anti-tumor immune responses observed in these patients are likely a consequence of immune system dysfunction contr

Externí odkaz: https://doaj.org/article/11a7490a2f674d479acb8ab8f2838e74

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