Výsledky vyhledávání - "Dennis, Warner"

Akademický článek

Linoleic Acid‐Derived Oxylipins Differentiate Early Stage Alcoholic Hepatitis From Mild Alcohol‐Associated Liver Injury

Autor: Dennis Warner, Vatsalya Vatsalya, Kara H. Zirnheld, Jeffrey B. Warner, Josiah E. Hardesty, John C. Umhau, Craig J. McClain, Krishnarao Maddipati, Irina A. Kirpich

Publikováno v: Hepatology Communications, Vol 5, Iss 6, Pp 947-960 (2021)

Alcohol‐associated liver disease (ALD) is a spectrum of liver disorders ranging from steatosis to steatohepatitis, fibrosis, and cirrhosis. Alcohol‐associated hepatitis (AH) is an acute and often severe form of ALD with substantial morbidity and

Externí odkaz: https://doaj.org/article/61ac43bc0cae4aebb0739cf5d68fbbaa

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Akademický článek

Fat-1 Transgenic Mice With Augmented n3-Polyunsaturated Fatty Acids Are Protected From Liver Injury Caused by Acute-On-Chronic Ethanol Administration

Autor: Jeffrey Warner, Josiah Hardesty, Ying Song, Rui Sun, Zhongbin Deng, Raobo Xu, Xinmin Yin, Xiang Zhang, Craig McClain, Dennis Warner, Irina Kirpich

Publikováno v: Frontiers in Pharmacology, Vol 12 (2021)

Alcohol-associated liver disease (ALD) is the leading cause of liver disease worldwide, and alcohol-associated hepatitis (AH), a severe form of ALD, is a major contributor to the mortality and morbidity due to ALD. Many factors modulate susceptibilit

Externí odkaz: https://doaj.org/article/fae533144bff40eaa6edbd77181aebcb

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Akademický článek

Soluble Epoxide Hydrolase Inhibition in Liver Diseases: A Review of Current Research and Knowledge Gaps

Autor: Jeffrey Warner, Josiah Hardesty, Kara Zirnheld, Craig McClain, Dennis Warner, Irina Kirpich

Publikováno v: Biology, Vol 9, Iss 6, p 124 (2020)

Emerging evidence suggests that soluble epoxide hydrolase (sEH) inhibition is a valuable therapeutic strategy for the treatment of numerous diseases, including those of the liver. sEH rapidly degrades cytochrome P450-produced epoxygenated lipids (epo

Externí odkaz: https://doaj.org/article/8a3a998b29c048919ef9706a126bd89c

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Hepatic Protein and Phosphoprotein Signatures of Alcohol-Associated Cirrhosis and Hepatitis

Autor: Josiah Hardesty, Le Day, Jeffrey Warner, Dennis Warner, Marina Gritsenko, Aliya Asghar, Andrew Stolz, Timothy Morgan, Craig McClain, Jon Jacobs, Irina Kirpich

Publikováno v: Am J Pathol
The American journal of pathology, vol 192, iss 7

Alcohol-associated liver disease is a global health care burden, with alcohol-associated cirrhosis (AC) and alcohol-associated hepatitis (AH) being two clinical manifestations with poor prognosis. The limited efficacy of standard of care for AC and A

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bf17f77e76e26deb3bdd9549851e461
https://europepmc.org/articles/PMC9253914/

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