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pro vyhledávání: '"Dennis, Reichert"'
Publikováno v:
Methods. 205:73-82
Post-transcriptional modifications play an important role in several processes, including translation, splicing, and RNA degradation in eukaryotic cells. To investigate the function of specific modifications it is of high interest to develop tools fo
Publikováno v:
Methods
Enzymatic modification of the 5′-cap is a versatile approach to modulate the properties of mRNAs. Transfer of methyl groups from S-adenosyl- l -methionine (AdoMet) or functional moieties from non-natural analogs by methyltransferases (MTases) allow
Autor:
Bart Jan Ravoo, Dennis Reichert, Andrea Rentmeister, Wolfgang Dörner, Birte Höcker, Horst Lechner, Helena Schepers, Julian Simke
Publikováno v:
RSC Chemical Biology
The spatial and temporal control of gene expression at the post-transcriptional level is essential in eukaryotic cells and developing multicellular organisms. In recent years optochemical and optogenetic tools have enabled the manipulation and invest
Publikováno v:
Chemical Science. 12:4383-4388
Gene expression is tightly regulated in all domains of life, with post-transcriptional regulation being more pronounced in higher eukaryotes. Optochemical and optogenetic approaches enable the actuation of many underlying processes by light, which is
Publikováno v:
Chemical Science
Gene expression is tightly regulated in all domains of life, with post-transcriptional regulation being more pronounced in higher eukaryotes. Optochemical and optogenetic approaches enable the actuation of many underlying processes by light, which is
Autor:
Bernd Nidetzky, Dennis Reichert, Álvaro Gómez Baraibar, Samiro Bojarra, Marius Grote, Carolin Mügge, Alexander Dennig, Robert Kourist
Publikováno v:
ChemCatChem. 10:1192-1201
Publikováno v:
Chemical Science. 8:7947-7953
Site-specific alkylation of complex biomolecules is critical for late-stage product diversification as well as post-synthetic labeling and manipulation of proteins and nucleic acids. Promiscuous methyltransferases in combination with analogs of S-ade
Autor:
Dennis Reichert, Harald Gröger, Svenja Seger, Álvaro Gómez Baraibar, Carolin Mügge, Robert Kourist
Publikováno v:
Angewandte Chemie. 128:15043-15047
Die Kombination von Enzymen mit herkommlichen Katalysatoren ermoglicht die Verbindung hoher Selektivitat ersterer mit der Vielseitigkeit letzterer. Eine grose Herausforderung dieses Ansatzes besteht in den sehr unterschiedlichen optimalen Reaktionsbe
Autor:
Carolin Mügge, Svenja Seger, Dennis Reichert, Harald Gröger, Álvaro Gómez Baraibar, Robert Kourist
The combination of enzymes with traditional chemical catalysts unifies the high selectivity of the former with the versatility of the latter. A major challenge of this approach is the difference in the optimal reaction conditions for each catalyst ty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95d434140396f27aa1c396166951b1b3
https://doi.org/10.1002/anie.201607777
https://doi.org/10.1002/anie.201607777