Zobrazeno 1 - 10 of 28 pro vyhledávání: '"Dennis, Doleschel"'
1
Akademický článek
Regorafenib enhances anti-PD1 immunotherapy efficacy in murine colorectal cancers and their combination prevents tumor regrowth
Autor: Dennis Doleschel, Sabine Hoff, Susanne Koletnik, Anne Rix, Dieter Zopf, Fabian Kiessling, Wiltrud Lederle
Publikováno v: Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-14 (2021)
Abstract Background Patients with advanced colorectal cancer (CRC) have a poor prognosis. Combinations of immunotherapies and anti-angiogenic agents are currently being evaluated in clinical trials. In this study, the multikinase inhibitor regorafeni
Externí odkaz: https://doaj.org/article/f1af03bb86884972b957d7874ccb7a22
Zobrazit plný text záznamu
2
Akademický článek
Nilotinib Enhances Tumor Angiogenesis and Counteracts VEGFR2 Blockade in an Orthotopic Breast Cancer Xenograft Model with Desmoplastic Response
Autor: Sara Zafarnia, Jessica Bzyl-Ibach, Igor Spivak, Yongping Li, Susanne Koletnik, Dennis Doleschel, Anne Rix, Sibylle Pochon, Isabelle Tardy, Seena Koyadan, Marc van Zandvoort, Moritz Palmowski, Fabian Kiessling, Wiltrud Lederle
Publikováno v: Neoplasia: An International Journal for Oncology Research, Vol 19, Iss 11, Pp 896-907 (2017)
Vascular endothelial growth factor (VEGF)/VEGF receptor (VEGFR)-targeted therapies predominantly affect nascent, immature tumor vessels. Since platelet-derived growth factor receptor (PDGFR) blockade inhibits vessel maturation and thus increases the
Externí odkaz: https://doaj.org/article/0bfad39e91c6449da9f7b6358df61396
Zobrazit plný text záznamu
3
Akademický článek
Non-invasive Imaging and Modeling of Liver Regeneration After Partial Hepatectomy
Autor: Sara Zafarnia, Anna Mrugalla, Anne Rix, Dennis Doleschel, Felix Gremse, Stephanie D. Wolf, Johannes F. Buyel, Ute Albrecht, Johannes G. Bode, Fabian Kiessling, Wiltrud Lederle
Publikováno v: Frontiers in Physiology, Vol 10 (2019)
The liver has a unique regenerative capability upon injury or partial resection. The regeneration process comprises a complex interplay between parenchymal and non-parenchymal cells and is tightly regulated at different scales. Thus, we investigated
Externí odkaz: https://doaj.org/article/6d73b8a10b2b444ea087b8c0d5efd028
Zobrazit plný text záznamu
4
Molecular Ultrasound Imaging Depicts the Modulation of Tumor Angiogenesis by Acetylsalicylic Acid
Autor: Flurin Mueller-Diesing, Wiltrud Lederle, Anne Rix, Susanne Koletnik, Dennis Doleschel, Maximilian Snelting, Felix Gremse, Fabian Kiessling
Publikováno v: International Journal of Molecular Sciences. 24:7060
Acetylsalicylic acid (ASA) is a well-established drug for heart attack and stroke prophylaxis. Furthermore, numerous studies have reported an anti-carcinogenic effect, but its exact mechanism is still unknown. Here, we applied VEGFR-2-targeted molecu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b438ce19301a3c185ba48eb4113f7dd0
https://doi.org/10.3390/ijms24087060
Zobrazit plný text záznamu
5
Regorafenib enhances anti-PD1 immunotherapy efficacy in murine colorectal cancers and their combination prevents tumor regrowth
Autor: Susanne Koletnik, Dennis Doleschel, Fabian Kiessling, Anne Rix, Wiltrud Lederle, Dieter Zopf, Sabine Hoff
Publikováno v: Journal of Experimental & Clinical Cancer Research : CR
Journal of experimental & clinical cancer research 40(1), 288 (2021). doi:10.1186/s13046-021-02043-0
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-14 (2021)
Journal of experimental & clinical cancer research 40(1), 288 (2021). doi:10.1186/s13046-021-02043-0
Published by Springer, Berlin ; Heidelberg
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab98cf9179bb969a3e3b7319e8b77865
http://europepmc.org/articles/PMC8436536
Zobrazit plný text záznamu
6
Change of Apoptosis and Glucose Metabolism in Lung Cancer Xenografts during Cytotoxic and Anti-Angiogenic Therapy Assessed by Annexin V Based Optical Imaging and 18F-FDG-PET/CT
Autor: Dennis Doleschel, Felix M. Mottaghy, F. A. Verburg, Felix Gremse, Karin Palmowski, Anne Rix, Moritz Palmowski, Jasmin Gross, Wiltrud Lederle, Fabian Kiessling
Publikováno v: Contrast Media & Molecular Imaging, 2021:6676337. Wiley Hindawi Partnership
Contrast media & molecular imaging 2021, (2021). doi:10.1155/2021/6676337
Contrast Media & Molecular Imaging, Vol 2021 (2021)
Contrast media & molecular imaging 2021, (2021). doi:10.1155/2021/6676337
Published by Hindawi, London
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63204e56692653932b019ac70d1cf857
https://cris.maastrichtuniversity.nl/en/publications/60ef079a-5c6c-4659-be2d-ce32e6d90177
Zobrazit plný text záznamu
7
Change of Apoptosis and Glucose Metabolism in Lung Cancer Xenografts during Cytotoxic and Anti-Angiogenic Therapy Assessed by Annexin V Based Optical Imaging and
Autor: Jasmin, Gross, Karin, Palmowski, Dennis, Doleschel, Anne, Rix, Felix, Gremse, Frederic, Verburg, Felix M, Mottaghy, Fabian, Kiessling, Wiltrud, Lederle, Moritz, Palmowski
Publikováno v: Contrast Media & Molecular Imaging
Methods For apoptosis imaging, the near-infrared probe Annexin Vivo750 was used in combination with fluorescence molecular tomography and microcomputed tomography (FMT/µCT). Glucose metabolism was assessed using 18F-FDG-PET/CT. Five groups of nude m
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::babddab48b2786c04d52635044cce573
https://pubmed.ncbi.nlm.nih.gov/34007252
Zobrazit plný text záznamu
8
Lipid-encapsulated siRNA for hepatocyte-directed treatment of advanced liver disease
Autor: Matthias Bartneck, MM Woitok, Dennis Doleschel, Fabian Kießling, Christian Trautwein, Francisco Javier Cubero, Miguel Eugenio Zoubek, Mohamed Ramadan Mohamed, Wiltrud Lederle
Publikováno v: Cell Death & Disease, 11(5):343. Nature Publishing Group
Cell Death and Disease, Vol 11, Iss 5, Pp 1-14 (2020)
Cell death & disease 11(5), 343 (2020). doi:10.1038/s41419-020-2571-4
Cell Death & Disease
Cell death & disease 11(5), 343 (2020). doi:10.1038/s41419-020-2571-4
Published by Nature Publishing Group, London [u.a.]
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da56f55e394bd093f617915e8c2b2156
https://cris.maastrichtuniversity.nl/en/publications/e8501311-ebd0-4352-9ab8-7b98f0e68849
Zobrazit plný text záznamu
10
Dual CTLA-4 and PD-L1 Blockade Inhibits Tumor Growth and Liver Metastasis in a Highly Aggressive Orthotopic Mouse Model of Colon Cancer
Autor: Fabian Kiessling, E. Fiegle, Susanne Koletnik, Dennis Doleschel, Anne Rix, Erawan Borkham-Kamphorst, Ralf Weiskirchen, Wiltrud Lederle
Publikováno v: Neoplasia 21(9), 932-944 (2019). doi:10.1016/j.neo.2019.07.006
Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 9, Pp 932-944 (2019)
Immune checkpoint inhibitors have shown clinical benefit in several cancer entities including metastatic microsatellite instable colorectal carcinomas. However, for the majority of metastatic colorectal carcinomas the potential and limitations of imm
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aa9820dfe2a05de7562c0345dc26993
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje