Zobrazeno 1 - 10
of 225
pro vyhledávání: '"Dennis, Christensen"'
Autor:
Joshua S. Woodworth, Vanessa Contreras, Dennis Christensen, Thibaut Naninck, Nidhal Kahlaoui, Anne-Sophie Gallouët, Sébastien Langlois, Emma Burban, Candie Joly, Wesley Gros, Nathalie Dereuddre-Bosquet, Julie Morin, Ming Liu Olsen, Ida Rosenkrands, Ann-Kathrin Stein, Grith Krøyer Wood, Frank Follmann, Thomas Lindenstrøm, Tu Hu, Roger Le Grand, Gabriel Kristian Pedersen, Rasmus Mortensen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Development of new vaccines tailored for difficult-to-target diseases is hampered by a lack of diverse adjuvants for human use, and none of the currently available adjuvants induce Th17 cells. Here, we develop a liposomal adjuvant, CAF®10b,
Externí odkaz:
https://doaj.org/article/247707a325064a6ea6e1237d4d196721
Autor:
Ruiying Wang, Lorena V N Oliveira, Maureen M Hester, Diana Carlson, Dennis Christensen, Charles A Specht, Stuart M Levitz
Publikováno v:
PLoS Pathogens, Vol 20, Iss 7, p e1012220 (2024)
The fungal infection, cryptococcosis, is responsible for >100,000 deaths annually. No licensed vaccines are available. We explored the efficacy and immune responses of subunit cryptococcal vaccines adjuvanted with Cationic Adjuvant Formulation 01 (CA
Externí odkaz:
https://doaj.org/article/f95efdf0739045df975e52daceeaec34
Autor:
Julie Zimmermann, Simon D. van Haren, Joann Diray-Arce, Ignatius Ryan Adriawan, Katharina Wørzner, Ricki T. Krog, Safia Guleed, Tu Hu, Rasmus Mortensen, Jes Dietrich, Sara M. Ø. Solbak, Ofer Levy, Dennis Christensen, Gabriel K. Pedersen
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-12 (2023)
Abstract Class-switching to IgG2a/c in mice is a hallmark response to intracellular pathogens. T cells can promote class-switching and the predominant pathway for induction of IgG2a/c antibody responses has been suggested to be via stimulation from T
Externí odkaz:
https://doaj.org/article/b2a5b6ac83564fccb7d1fc8c4727c789
Autor:
Marco Donia, Marie Christine Wulff Westergaard, Sine Reker Hadrup, Kalijn Bol, Inge Marie Svane, Arianna Draghi, Anders Jespersen, Sofie Kirial Mørk, Christina Westmose Yde, Torben Lorentzen, Mohammad Kadivar, Daniela Kleine-Kohlbrecher, Benedetta Albieri, Joachim Stoltenborg Granhøj, Signe Koggersbøl Skadborg, Annie Borch, Nadia Viborg Petersen, Nikolas Thuesen, Ida Svahn Rasmussen, Lars Vibe Andreasen, Rebecca Bach Dohn, Nis Noergaard, Anders Bundgaard Soerensen, Dennis Christensen, Jens Kringelum
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 5 (2024)
Background Neoantigens can serve as targets for T cell-mediated antitumor immunity via personalized neopeptide vaccines. Interim data from our clinical study NCT03715985 showed that the personalized peptide-based neoantigen vaccine EVX-01, formulated
Externí odkaz:
https://doaj.org/article/ba4e7a8820d44fe594ecfd552cb83643
Autor:
Geir P. Novik, Dennis Christensen
Publikováno v:
Royal Society Open Science, Vol 11, Iss 3 (2024)
Millions of tonnes of explosive remnants of war remain in nature and their volume is continuously growing. The explosive legacy of wars represents an increasing threat to the environment and societal safety and security. As munitions continue to dete
Externí odkaz:
https://doaj.org/article/f0185d0248ae4bf48228be8a48d73e4b
Autor:
Julen Tomás-Cortázar, Conor Quinn, Niamh Corcoran, Alfonso Blanco, Dennis Christensen, Siobhán McClean
Publikováno v:
Vaccine: X, Vol 17, Iss , Pp 100438- (2024)
There are no licensed vaccines to protect vulnerable populations from the potentially fatal tropical infection, melioidosis, despite its causative agent, Burkholderia pseudomallei, being endemic in tropical and subtropical regions. A promising vaccin
Externí odkaz:
https://doaj.org/article/26ddc909a64e40c2a9662ba435e356d9
Autor:
Nicolas Collin, Donata Medaglini, Arjen Sloots, Maria Lawrenz, Jan A.M. Langermans, Roger Le Grand, Norbert Stockhofe-Zurwieden, Francesca Morelli, Fabrice Laurent, Frédéric Lantier, Alexandre Dobly, Dennis Christensen, Joaquim Segalés, H. M. Dockrell, Mei Mei Ho, Ole Olesen, Tom H.M. Ottenhoff, Frank A.W. Verreck, Stefan Jungbluth, Sven Arnouts, Manuel J. T. Carrondo, David Morrow, Fran Van Heuverswyn, Carlos A. Guzman, Anton Ussi, Monika Slezak, Hilde Depraetere, William Martin
Publikováno v:
F1000Research, Vol 12 (2023)
Background Research infrastructures are facilities or resources that have proven fundamental for supporting scientific research and innovation. However, they are also known to be very expensive in their establishment, operation and maintenance. As by
Externí odkaz:
https://doaj.org/article/9b023d85cc924663a81aea22af5b7578
Autor:
Sergi López-Serrano, Yasser S. Mahmmod, Dennis Christensen, Thomas Ebensen, Carlos A. Guzmán, Fernando Rodríguez, Joaquim Segalés, Virginia Aragón
Publikováno v:
Vaccine: X, Vol 14, Iss , Pp 100330- (2023)
Glaesserella parasuis is a Gram-negative bacterium that colonizes the upper airways of swine, capable of causing a systemic infection called Glässer’s disease. This disease is more frequent in young post-weaning piglets. Current treatments against
Externí odkaz:
https://doaj.org/article/3bbcef62e8bf4f1a847924162df8a075
Autor:
Julie Zimmermann, Simon D. van Haren, Joann Diray-Arce, Ignatius Ryan Adriawan, Katharina Wørzner, Ricki T. Krog, Safia Guleed, Tu Hu, Rasmus Mortensen, Jes Dietrich, Sara M. Ø. Solbak, Ofer Levy, Dennis Christensen, Gabriel K. Pedersen
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/63c1f7f21415417bb945389bc0db3129
Autor:
Dennis Christensen
Publikováno v:
Pharmaceutics, Vol 16, Iss 1, p 12 (2023)
Modern vaccine development is having a golden period, with a variety of novel subunit technologies being introduced into clinical development in recent years. This opens the opportunity to find the best platform to use for novel vaccine antigen candi
Externí odkaz:
https://doaj.org/article/03781271dc7043cf8b509f5596df94c1