Výsledky vyhledávání - "Denmeade, SR"

Mesenchymal stem cell infiltration during neoplastic transformation of the human prostate

Autor: Brennen, WN, Zhang, B, Kulac, I, Kisteman, LN, Antony, L, Wang, H, Meeker, AK, De Marzo, AM, Garraway, IP, Denmeade, SR, Isaacs, JT

Publikováno v: Oncotarget, vol 8, iss 29
Brennen, WN; Zhang, B; Kulac, I; Kisteman, LN; Antony, L; Wang, H; et al.(2017). Mesenchymal stem cell infiltration during neoplastic transformation of the human prostate. ONCOTARGET, 8(29), 46710-46727. doi: 10.18632/oncotarget.17362. UCLA: Retrieved from: http://www.escholarship.org/uc/item/8372v006

Mesenchymal Stem Cells (MSCs) have been identified in prostate cancer, raising the critical question of their physical and temporal source. Therefore, MSCs were quantified and characterized in benign and malignant prostate tissue representing differe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::69c87c71d1fdd5fcc7665acc5499ed45
https://escholarship.org/uc/item/8372v006

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A Phase I Study of Muscadine Grape Skin Extract in Men with Biochemically Recurrent Prostate Cancer: Safety, Tolerability, and Dose Determination

Autor: Paller, CJ, Rudek, MA, Zhou, XC, Wagner, WD, Hudson, TS, Anders, N, Hammers, HJ, Dowling, D, King, S, Antonarakis, ES, Drake, CG, Eisenberger, MA, Denmeade, SR, Rosner, GL, Carducci, MA

New therapies are being explored as therapeutic options for men with biochemically recurrent prostate cancer (BRPC) who wish to defer androgen deprivation therapy. MPX is pulverized muscadine grape (Vitis rotundifolia) skin that contains ellagic acid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a134db09af25b7ce080706b6ec0ec90f
https://europepmc.org/articles/PMC4537354/

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Molecular insights into substrate specificity of prostate specific antigen through structural modeling

Autor: Singh, P, LeBeau, A, Lilja, H, Denmeade, SR, Isaacs, J

Publikováno v: Proteins. 77(4)

Prostate Specific Antigen's (PSA) role as a biomarker for prostate cancer is well established but the physiological role of its serine protease activity in the pathobiology of normal prostate and prostate carcinogenesis remains largely unknown. In li

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::8e0ff055ed5b2ed1329bdc9d9424a6e5
http://ora.ox.ac.uk/objects/uuid:55399c99-5998-45d0-be76-a753a815a751

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Activation of latent protease function of pro-hK2, but not pro-PSA, involves autoprocessing

Autor: Denmeade, SR, Lövgren, J, Khan, SR, Lilja, H, Isaacs, J

Publikováno v: The Prostate. 48(2)

BACKGROUND: Human glandular kallikrein 2 (hK2) and prostate-specific antigen (PSA) are members of an extensive kallikrein family of proteases. Both proteases are secreted as zymogens or proenzymes containing a seven amino acid propeptide that must be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::6a1097c236a3d420dbc6f3091ecf9e67
http://ora.ox.ac.uk/objects/uuid:4a8ad6ae-ae7b-412d-9659-25f878eec58d

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