Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Deniz N. Dolcen"'
Autor:
Deniz N. Dolcen, Suzanne D. Conzen, Rita Nanda, Randy F. Sweis, Ken Hatogai, Aaron Miller, Marie S. Dreyer, Anna Biernacka
Publikováno v:
Cancer Research. 81:PS18-01
Background: Triple-negative breast cancer (TNBC) with high glucocorticoid receptor activity (GR-high) is associated with a high risk of relapse and chemotherapy resistance. Glucocorticoids (GC) are essential for the regulation of immune and inflammat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30dbecb726c4854636361f08bc6d1f85
https://doi.org/10.1158/1538-7445.sabcs20-ps18-01
https://doi.org/10.1158/1538-7445.sabcs20-ps18-01
Publikováno v:
Cancer Research. 80:1290-1290
Background: Post-transcriptional RNA methylation is implicated as a mechanism regulating gene expression associated with stem cell differentiation and malignant transformation. N6-methyladenosine (m6A) is the most abundant eukaryotic mRNA methylation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8bc2a2280273ae5e29b766617795a332
https://doi.org/10.1158/1538-7445.am2020-1290
https://doi.org/10.1158/1538-7445.am2020-1290
Autor:
Xiaomeng Wang, Rita Nanda, Diana West Szymanski, Suzanne D. Conzen, Ananth Panchamukhi, Deniz N. Dolcen, Randy F. Sweis
Publikováno v:
Cancer Research. 79:2812-2812
Background: Variation in the infiltration of TNBC immune microenvironment is not well understood. Our lab previously demonstrated that high glucocorticoid receptor (GR; nuclear hormone receptor) activity in TNBC models is associated with tumor cell-i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e608653eedf8621d608421b8b517836
https://doi.org/10.1158/1538-7445.am2019-2812
https://doi.org/10.1158/1538-7445.am2019-2812
Autor:
Suzanne D. Conzen, Caroline R. Kim, Gini F. Fleming, Deniz N. Dolcen, Eva Tonsing-Carter, Kathleen R. Bowie, Ryan V. Harkless
Publikováno v:
Cancer Research. 78:2541-2541
Background: A recent effort to distinguish early-stage TNBC based on outcome and to expose driver pathways using gene profiling/cluster analysis divided TNBC into four subtypes- basal-like, mesenchymal, immunomodulatory, and luminal androgen receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e07a5abfc329ab1ed66947cc4d25102
https://doi.org/10.1158/1538-7445.am2018-2541
https://doi.org/10.1158/1538-7445.am2018-2541
Autor:
Ryan Abo, Rachel R. Paquette, Laura E. MacConaill, Angelica Laing, Aaron R. Thorner, Deniz N. Dolcen, Ling Lin, Matthew Meyerson, Liuda Ziaugra, William C. Hahn, Luc de Waal, Paul Van Hummelen, Samuel S. Hunter, Matthew D. Ducar
Publikováno v:
Cancer Research. 75:4867-4867
RNA sequencing (RNASeq) provides the ability to comprehensively assay the transcriptome in a high-throughput manner. Current there are a variety of library preparation methodologies for measuring and sequencing the transcriptome depending on (a) the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97830d62c12a8080c4926bcc97744c19
https://doi.org/10.1158/1538-7445.am2015-4867
https://doi.org/10.1158/1538-7445.am2015-4867
Autor:
Marc Breneiser, Laura E. MacConaill, Ling Lin, Rachel R. Paquette, Aaron R. Thorner, Liuda Ziaugra, Matthew Meyerson, Ryan Abo, Angelica Laing, Paul Van Hummelen, Matthew D. Ducar, Luc de Waal, Deniz N. Dolcen, Bruce M. Wollison, William C. Hahn
Publikováno v:
Cancer Research. 75:1115-1115
RNA sequencing (RNA-seq) is a transcriptome profiling technology that provides multiple levels of insight into the genome. In addition to expression levels (transcript abundance), it generates endpoints such as alternative splicing, somatic mutations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b723b24f0895ea302455c3d61200af82
https://doi.org/10.1158/1538-7445.am2015-1115
https://doi.org/10.1158/1538-7445.am2015-1115
Autor:
Robert T. Jones, Ravali Adusumilli, Aaron R. Thorner, Laura Schubert, Matthew D. Ducar, Liuda Ziaugra, William C. Hahn, Laura E. MacConaill, Paul Van Hummelen, Deniz N. Dolcen, Ashwini Sunkavalli, Matthew Meyerson, Ling Lin, Jack R. Lepine
Publikováno v:
Cancer Research. 74:3583-3583
Next-generation sequencing (NGS) is increasingly used in the laboratory and clinic to identify genomic factors contributing to tumorigenesis, such as somatic mutations, DNA insertions and deletions, transcriptome and epigenetic changes, and chromosom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b55ff830ea9591faae36eadf182831b9
https://doi.org/10.1158/1538-7445.am2014-3583
https://doi.org/10.1158/1538-7445.am2014-3583
Autor:
Liuda Ziaugra, Matthew Meyerson, Paul Van Hummelen, Matthew D. Ducar, Robert T. Jones, Ashwini Sunkavalli, William C. Hahn, Laura E. MacConaill, Mikenah Vega, Laura Schubert, Aaron R. Thorner, Ling Lin, Deniz N. Dolcen, Jack R. Lepine
Publikováno v:
Cancer Research. 74:4286-4286
Formalin fixation followed by paraffin embedding (FFPE) is the most widely used method of tissue preservation and often used in the clinical setting for cancer specimens. However, this process of fixation has negative consequences on the quality of e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2521374bc47b2493ffbf80db0c694394
https://doi.org/10.1158/1538-7445.am2014-4286
https://doi.org/10.1158/1538-7445.am2014-4286