Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Deniz Ekinci"'
Autor:
Hasan Yakan, Gürkan Bilir, Şükriye Çakmak, Ömer Taş, Nalan Türköz Karakullukçu, Ercan Soydan, Halil Kütük, Coşkun Güçlü, Murat Şentürk, Tayfun Arslan, Seyhan Öztürk, Ercüment Aksakal, Deniz Ekinci
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
A series of sulfenimide derivatives (1a-i) were investigated as inhibitors of human (hCA-I, hCA-II) and bovine (bCA) carbonic anhydrase enzymes. The compounds were synthesised by the reaction of substituted thiophenols with phthalimide by means of an
Externí odkaz:
https://doaj.org/article/4cc01568b6294ae28b504068ea8a4119
Publikováno v:
Aquaculture Reports, Vol 29, Iss , Pp 101519- (2023)
In this study, the effects of alternative lipid sources on growth, mineral content, proximate composition, fatty acid profile and gene expression of rainbow trout were investigated. Four different diets were prepared with isonitrogenous and isolipid
Externí odkaz:
https://doaj.org/article/e371fc7d5ca742c79a2e2b34384ee42b
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 885-894 (2021)
Here we investigated the effects of different levels of royal jelly in zebrafish (Danio rerio) diets [0.0% (D1); 0.1% (D2); 0.4% (D3); 1.6% (D4) vs 6.4% (D5)] on the activity and expression profiles of superoxide dismutase, catalase, glutathione redu
Externí odkaz:
https://doaj.org/article/359247fa4a3342b79ae95947ee4ae07e
Autor:
Yazgı Dizdaroglu, Canan Albay, Tayfun Arslan, Abdulilah Ece, Emir A. Turkoglu, Asiye Efe, Murat Senturk, Claudiu T. Supuran, Deniz Ekinci
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 289-297 (2020)
In this study, newly synthesised compounds 6, 8, 10 and other compounds (1–5, 7 and 9) and their inhibitory properties against the human isoforms hCA I and hCA II were reported for the first time. Compounds 1–10 showed effective inhibition profil
Externí odkaz:
https://doaj.org/article/e7685750dc7d44148b35366b89aefeed
Autor:
Ercan Soydan, Ahmet Can Olcay, Gürkan Bilir, Ömer Taş, Murat Şentürk, Deniz Ekinci, Claudiu T. Supuran
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 1923-1927 (2020)
Carbonic anhydrase (CA, EC 4.2.1.1) plays crucial physiological roles in many different organisms, such as in pH regulation, ion transport, and metabolic processes. CA was isolated from the European bee Apis mellifera (AmCA) spermatheca and inhibitor
Externí odkaz:
https://doaj.org/article/eba67b110b68423288ed50d59eee5653
Autor:
Huseyin Cavdar, Murat Senturk, Murat Guney, Serdar Durdagi, Gulru Kayik, Claudiu T. Supuran, Deniz Ekinci
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 429-437 (2019)
Acetylcholinesterase (AChE) and Butyrylcholinesterase (BuChE) inhibitors are interesting compounds for different therapeutic applications, among which Alzheimer’s disease. Here, we investigated the inhibition of these cholinesterases with uracil de
Externí odkaz:
https://doaj.org/article/784ec375b5d14723b3802f7ed92de447
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 51-54 (2019)
Glutathione reductase (GR) is a crucial antioxidant enzyme which is responsible for the maintenance of antioxidant GSH molecule. Antimalarial effects of some chemical molecules are attributed to their inhibition of GR, thus inhibitors of this enzyme
Externí odkaz:
https://doaj.org/article/a3b75cf3f9af4ba0ba9bbfaf35f05c8c
Autor:
Murat Tas, Esra Senturk, Deniz Ekinci, Ramazan Demirdag, Veysal Comakli, Metin Bayram, Murat Akyuz, Murat Senturk, Claudiu T. Supuran
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 218-223 (2019)
The effects of high-intensity interval and continuous exercise on erythrocytes carbonic anhydrase (CA, EC 4.2.1.1) activity levels were scarcely investigated up until now. Here we present a study focused on the CA activity from erythrocytes of athlet
Externí odkaz:
https://doaj.org/article/917f7672151743d1a2d2107343b2e7fa
Autor:
Deniz EKİNCİ, Aysun ÖZKAN
Publikováno v:
Cukurova Medical Journal, Vol 42, Iss 3, Pp 546-551 (2017)
Yapılan pek çok araştırmada hem yeni tanı multipl miyelomda hem de otolog kök hücre nakli dahil kemoterapötik tedaviler sonrası hastalarda regülatör T hücrelerin artışı söz konusudur. Multipl miyelom habis bir plazma hücre hastalığ
Externí odkaz:
https://doaj.org/article/04f1caf0372b49bfb8ca85305d98d4af
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 32, Iss 1, Pp 74-77 (2017)
Inhibitors of carbonic anhydrase (CA) have been carried out in many therapeutic applications, especially antiglaucoma activity. In this study, we investigated some uracil derivatives (4–12) to inhibit human CA I (hCA I) and II (hCA II) isoenzymes.
Externí odkaz:
https://doaj.org/article/60065937490146db81b9691811574578