Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Deniz Bartsch"'
Autor:
Hyun Ju Lee, Deniz Bartsch, Cally Xiao, Santiago Guerrero, Gaurav Ahuja, Christina Schindler, James J. Moresco, John R. Yates, Fátima Gebauer, Hisham Bazzi, Christoph Dieterich, Leo Kurian, David Vilchez
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-19 (2017)
Unlike transcriptional regulation of hESC identity, little is known post-transcriptionally. Here, the authors show that the RNA binding protein CSDE1 regulates core components of hESC identity, neurectoderm commitment and neurogenesis to maintain plu
Externí odkaz:
https://doaj.org/article/8b637ecfb83f4e0ea34de34086340b09
Autor:
Deniz Bartsch, Kaustubh Kalamkar, Gaurav Ahuja, Jan-Wilm Lackmann, Jürgen Hescheler, Timm Weber, Hisham Bazzi, Massimiliano Clamer, Sasha Mendjan, Argyris Papantonis, Leo Kurian
Publikováno v:
Science Advances. 9
The blueprints of developing organs are preset at the early stages of embryogenesis. Transcriptional and epigenetic mechanisms are proposed to preset developmental trajectories. However, we reveal that the competence for the future cardiac fate of hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::591fe2549600e40d95f38b9d8fadcca9
https://doi.org/10.1126/sciadv.ade1792
https://doi.org/10.1126/sciadv.ade1792
Autor:
Saskia Galanjuk, Etta Zühr, Arif Dönmez, Deniz Bartsch, Leo Kurian, Julia Tigges, Ellen Fritsche
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 6; Pages: 3295
The evaluation of substances for their potency to induce embryotoxicity is controlled by safety regulations. Test guidelines for reproductive and developmental toxicity rely mainly on animal studies, which make up the majority of animal usage in regu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b44d823aee5618fd17907d01d014e11
https://pubmed.ncbi.nlm.nih.gov/35328717
https://pubmed.ncbi.nlm.nih.gov/35328717
Autor:
Daniel Bender, Deniz Bartsch, Burkard Stueve, Sebahattin Cirak, Stephan Waltz, Leo Kurian, Guenter Schwarz, Alexander T. Kaczmarek, Jose Angel Santamaria-Araujo
Publikováno v:
Human Molecular Genetics. 28:2885-2899
Sulfite oxidase (SO) is encoded by the nuclear SUOX gene and catalyzes the final step in cysteine catabolism thereby oxidizing sulfite to sulfate. Oxidation of sulfite is dependent on two cofactors within SO, a heme and the molybdenum cofactor (Moco)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e44257d27959cc8fedf1ff5ce58b1dff
https://doi.org/10.1093/hmg/ddz109
https://doi.org/10.1093/hmg/ddz109
Autor:
Hella S. Brönneke, Emilio Tarcitano, Markus Heine, Peter Frommolt, Nils R. Hansmeier, Trieu-My Van, Marta Pradas-Juni, Jan Mauer, George A. Garinis, Deniz Bartsch, Sajjad Khani, Susanne Brodesser, Catherina Baitzel, Matteo Oliverio, Marcelo A. Mori, Elena Schmidt, Jens C. Brüning, Hans Hilpert, Sandra Konieczka, Jan-Wilhelm Kornfeld, Jörg Heeren
Publikováno v:
Nature Cell Biology. 18:328-336
Activation of brown adipose tissue (BAT) controls energy homeostasis in rodents and humans and has emerged as an innovative strategy for the treatment of obesity and type 2 diabetes mellitus. Here we show that ageing- and obesity-associated dysfuncti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed436f6b2bb396c40a0b415a3485d74e
https://doi.org/10.1038/ncb3316
https://doi.org/10.1038/ncb3316
Autor:
Agapios Sachinidis, Natalia Emilse Vargas, Juergen Hescheler, Julia Franzen, Ivan G. Costa, Deniz Bartsch, Marie Gramm, Lilija Brant, Argyris Papantonis, Alvaro Rada-Iglesias, Joseph Chao-Chung Kuo, Nicole Russ, Meena Kanduri, Tsun-Po Yang, Chandrasekhar Kanduri, Jens-Peter Derks, Leo Kurian, Gaurav Ahuja, Jan-Erik Messling, Theodore Georgomanolis, Wenjie Yao, Rizwan Rehimi, Stefan Frank, Yulia Kargapolova, Martin Peifer, Vijay Suresh Akhade, Raja Ghazanfar Ali Sahito, Alina Kuroczik
Publikováno v:
Cell stem cell. 24(2)
Human protein-coding genes are often accompanied by divergently transcribed non-coding RNAs whose functions, especially in cell fate decisions, are poorly understood. Using an hESC-based cardiac differentiation model, we define a class of divergent l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dac29369f1efc75f28b1058582b5e2dc
https://pubmed.ncbi.nlm.nih.gov/30554961
https://pubmed.ncbi.nlm.nih.gov/30554961
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1724
A substantial proportion of the currently annotated genes in eukaryotes are proposed to function as RNA molecules (200 bp) with no significant protein coding potential, currently classified as long noncoding RNAs (lncRNA). A distinct subgroup of lncR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8856a3d4b3af38d545e4a03a4e125b22
https://pubmed.ncbi.nlm.nih.gov/29322448
https://pubmed.ncbi.nlm.nih.gov/29322448
Publikováno v:
Methods in Molecular Biology ISBN: 9781493975617
A substantial proportion of the currently annotated genes in eukaryotes are proposed to function as RNA molecules (>200 bp) with no significant protein coding potential, currently classified as long noncoding RNAs (lncRNA). A distinct subgroup of lnc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3db52bc14d13e9e32bf6dd39be99b5e7
https://doi.org/10.1007/978-1-4939-7562-4_13
https://doi.org/10.1007/978-1-4939-7562-4_13
Autor:
Gaurav Ahuja, John R. Yates, Fátima Gebauer, Deniz Bartsch, Christoph Dieterich, Santiago Guerrero, Leo Kurian, Christina Schindler, Hisham Bazzi, David Vilchez, Hyun Ju Lee, Cally Xiao, James J. Moresco
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-19 (2017)
Nature Communications
Nature Communications
While the transcriptional network of human embryonic stem cells (hESCs) has been extensively studied, relatively little is known about how post-transcriptional modulations determine hESC function. RNA-binding proteins play central roles in RNA regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::567eaa5c9ab186a3d46409ffef169a62
http://hdl.handle.net/10230/34962
http://hdl.handle.net/10230/34962
Autor:
Per Kogner, Tommy Martinsson, Anne Engesser, Tanmoy Mondal, Levent M. Akyürek, Leo Kurian, Matthias Fischer, Christoph Bartenhagen, Lily Deland, Sashidhar Bandaru, Deniz Bartsch, Chandrasekhar Kanduri, Santhilal Subhash, Agnete Kirkeby, Sanhita Mitra, Caroline Miranda, Helena Carén, Falk Hertwig, Larissa Traxler, Prasanna Kumar Juvvuna, Sara Wernig-Zorc, Maite Huarte, Subazini Thankaswamy Kosalai, Ruth Volland, Meena Kanduri
Publikováno v:
Cancer Cell. 33:417-434.e7
Trait-associated loci often map to genomic regions encoding long noncoding RNAs (lncRNAs), but the role of these lncRNAs in disease etiology is largely unexplored. We show that a pair of sense/antisense lncRNA (6p22lncRNAs) encoded by CASC15 and NBAT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69e182b3bdb3b9b4e250aee5133ba9f1
https://doi.org/10.1016/j.ccell.2018.01.020
https://doi.org/10.1016/j.ccell.2018.01.020