Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Deniz A Ucar"'
Autor:
Tiffany C Chang, Margarite D Matossian, Steven Elliott, Hope E Burks, Rachel A Sabol, Deniz A Ucar, Henri Wathieu, Jovanny Zabaleta, Luis Del Valle, Sukhmani Gill, Elizabeth Martin, Adam I Riker, Lucio Miele, Bruce A Bunnell, Matthew E Burow, Bridgette M Collins-Burow
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0251106 (2021)
[This corrects the article DOI: 10.1371/journal.pone.0226464.].
Externí odkaz:
https://doaj.org/article/af0fed20a0a946dba307bf3dd7112a62
Autor:
Tiffany C Chang, Margarite D Matossian, Steven Elliott, Hope E Burks, Rachel A Sabol, Deniz A Ucar, Henri Wathieu, Jovanny Zabaleta, Luis Del Valle, Sukhmani Gill, Elizabeth Martin, Adam I Riker, Lucio Miele, Bruce A Bunnell, Matthew E Burow, Bridgette M Collins-Burow
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0226464 (2020)
Metaplastic breast carcinoma (MBC) is a clinically aggressive and rare subtype of breast cancer, with similar features to basal-like breast cancers. Due to rapid growth rates and characteristic heterogeneity, MBC is often unresponsive to standard che
Externí odkaz:
https://doaj.org/article/8167b126290f4ef29efb642a847dccf8
Autor:
Fokhrul Hossain, Deniz A. Ucar, Giulia Monticone, Yong Ran, Samarpan Majumder, Kristina Larter, Hanh Luu, Dorota Wyczechowska, Soroor Heidari, Keli Xu, Sudarvili Shanthalingam, Margarite Matossian, Yaguang Xi, Matthew Burow, Bridgette Collins-Burow, Luis Del Valle, Chindo Hicks, Jovanny Zabaleta, Todd Golde, Barbara Osborne, Lucio Miele
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionTriple-negative breast cancer (TNBC) comprises a heterogeneous group of clinically aggressive tumors with high risk of recurrence and metastasis. Current pharmacological treatment options remain largely limited to chemotherapy. Despite pr
Externí odkaz:
https://doaj.org/article/04b72879c8aa4137addccea9bc2f8f2b
Targeting the Cbl-b-Notch1 axis as a novel immunotherapeutic strategy to boost CD8+ T-cell responses
Autor:
Giulia Monticone, Zhi Huang, Fred Csibi, Silvana Leit, David Ciccone, Ameya S. Champhekar, Jermaine E. Austin, Deniz A. Ucar, Fokhrul Hossain, Salome V. Ibba, A. Hamid Boulares, Nicholas Carpino, Keli Xu, Samarpan Majumder, Barbara A. Osborne, Christine Loh, Lucio Miele
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
A critical feature of cancer is the ability to induce immunosuppression and evade immune responses. Tumor-induced immunosuppression diminishes the effectiveness of endogenous immune responses and decreases the efficacy of cancer immunotherapy. In thi
Externí odkaz:
https://doaj.org/article/f8e940e37817407f8336c28c349fbf51
Autor:
Van T. Hoang, Margarite D. Matossian, Deniz A. Ucar, Steven Elliott, Jacqueline La, Maryl K. Wright, Hope E. Burks, Aaron Perles, Fokhrul Hossain, Connor T. King, Valentino E. Browning, Jacob Bursavich, Fang Fang, Luis Del Valle, Akshita B. Bhatt, Jane E. Cavanaugh, Patrick T. Flaherty, Muralidharan Anbalagan, Brian G. Rowan, Melyssa R. Bratton, Kenneth P. Nephew, Lucio Miele, Bridgette M. Collins-Burow, Elizabeth C. Martin, Matthew E. Burow
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Conventional mitogen-activated protein kinase (MAPK) family members regulate diverse cellular processes involved in tumor initiation and progression, yet the role of ERK5 in cancer biology is not fully understood. Triple-negative breast cancer (TNBC)
Externí odkaz:
https://doaj.org/article/200b22265dbe421ba0329786d0153f68
Autor:
Fokhrul Hossain, Claudia Sorrentino, Deniz A. Ucar, Yin Peng, Margarite Matossian, Dorota Wyczechowska, Judy Crabtree, Jovanny Zabaleta, Silvana Morello, Luis Del Valle, Matthew Burow, Bridgette Collins-Burow, Antonio Pannuti, Lisa M. Minter, Todd E. Golde, Barbara A. Osborne, Lucio Miele
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
Triple negative breast cancer (TNBC) patients have high risk of recurrence and metastasis, and current treatment options remain limited. Cancer stem-like cells (CSCs) have been linked to cancer initiation, progression and chemotherapy resistance. Not
Externí odkaz:
https://doaj.org/article/440b0deb8e4747ffb4412b3c0cdbe915
Autor:
Fokhrul Hossain, Samarpan Majumder, Deniz A. Ucar, Paulo C. Rodriguez, Todd E. Golde, Lisa M. Minter, Barbara A. Osborne, Lucio Miele
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Cancer immunotherapy, which stimulates or augments host immune responses to treat malignancies, is the latest development in the rapidly advancing field of cancer immunology. The basic principles of immunotherapies are either to enhance the functions
Externí odkaz:
https://doaj.org/article/43007cad3d39406fad720a3813534bd6
Autor:
Van T. Hoang, Jacqueline La, Brian G. Rowan, Saloni Patel, Aaron Buechlein, Matthew E. Burow, Bridgette M. Collins-Burow, Margarite D. Matossian, Lucio Miele, Douglas B. Rusch, Akshita B. Bhatt, Murali Anbalagan, Douglas B. Chrisey, Thomas D. Wright, Jane E. Cavanaugh, Kristine Hoang, Steven Elliott, Patrick T. Flaherty, Kenneth P. Nephew, Deniz A. Ucar, Theresa B. Phamduy, Hope E. Burks
Publikováno v:
Journal of Cellular Biochemistry. 122:835-850
Triple-negative breast cancer (TNBC) presents a clinical challenge due to the aggressive nature of the disease and a lack of targeted therapies. Constitutive activation of the mitogen-activated protein kinase (MAPK)/extracellular signal-regulated kin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33a2097f8e83f57573f0be34b12fd266
https://doi.org/10.1002/jcb.29916
https://doi.org/10.1002/jcb.29916
Autor:
Nirav Kapadia, Thomas J. Yan, Van T. Hoang, Steven Elliott, Margarite D. Matossian, David H. Drewry, Douglas B. Rusch, Fang Fang, Deniz A. Ucar, Lucio Miele, Khoa Nguyen, Carrow I. Wells, Hope E. Burks, William J. Zuercher, Jovanny Zabaleta, Matthew E. Burow, Tiffany R. Chang, Rachel A. Sabol, Bruce A. Bunnell, Kenneth P. Nephew, Aaron Buechlein, Gabrielle O. Windsor, Bridgette M. Collins-Burow
Publikováno v:
Anticancer Drugs
Breast cancer affects women globally; the majority of breast cancer-related mortalities are due to metastasis. Acquisition of a mesenchymal phenotype has been implicated in the progression of breast cancer cells to an invasive, metastatic state. Trip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5232d165c921188e2eb0b94b942d76dd
https://doi.org/10.1097/cad.0000000000000962
https://doi.org/10.1097/cad.0000000000000962
Autor:
Giulia Monticone, Fred Csibi, Silvana Leit, David Ciccone, Ameya S. Champhekar, Jermaine E. Austin, Deniz A. Ucar, Fokhrul Hossain, Zhi Huang, Salome V. Ibba, A. Hamid Boulares, Nicholas Carpino, Samarpan Majumder, Keli Xu, Barbara A. Osborne, Christine Loh, Lucio Miele
A critical feature of cancer is the ability to induce immunosuppression and evade immune responses. Tumor-induced immunosuppression diminishes the efficacy of endogenous immune responses and decreases the efficacy of cancer immunotherapy. In this stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f1499160016e9fd40cbe8738775d92d
https://doi.org/10.1101/2022.03.15.484378
https://doi.org/10.1101/2022.03.15.484378
