Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Deniz, Cizmeci"'
Autor:
Nadege Nziza, Deniz Cizmeci, Leela Davies, Edward B. Irvine, Wonyeong Jung, Brooke A. Fenderson, Marwou de Kock, Willem A. Hanekom, Kees L. M. C. Franken, Cheryl L. Day, Tom H. M. Ottenhoff, Galit Alter
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/01712ffb53764dccb83c5798019f95b2
Autor:
Paulina Kaplonek, Deniz Cizmeci, Jessica Shih-Lu Lee, Sally A. Shin, Stephanie Fischinger, Philipe Gobeil, Stéphane Pillet, Nathalie Charland, Brian J. Ward, Galit Alter
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-11 (2023)
Abstract Despite the success of existing COVID-19 vaccine platforms, the persistent limitations in global deployment of vaccines and waning immunity exhibited by many of the currently deployed vaccine platforms have led to perpetual outbreaks of SARS
Externí odkaz:
https://doaj.org/article/d55dbfe42ce74d4cbb08ac3c06582bd4
Autor:
Iman Satti, Rachel E. Wittenberg, Shuailin Li, Stephanie A. Harris, Rachel Tanner, Deniz Cizmeci, Ashley Jacobs, Nicola Williams, Humphrey Mulenga, Helen A. Fletcher, Thomas J. Scriba, Michele Tameris, Mark Hatherill, Helen McShane
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
The identification of immune correlates of protection in humans would inform on the design and development of tuberculosis vaccine candidates. In this work, authors examine samples collected from South African infants, to determine whether the correl
Externí odkaz:
https://doaj.org/article/fe708fb5f5134f818664bd801fc66d30
Autor:
Leela R.L. Davies, Malisa T. Smith, Deniz Cizmeci, Stephanie Fischinger, Jessica Shih-Lu Lee, Lenette L. Lu, Erik D. Layton, Alison D. Grant, Katherine Fielding, Catherine M. Stein, W. Henry Boom, Thomas R. Hawn, Sarah M. Fortune, Robert S. Wallis, Gavin J. Churchyard, Galit Alter, Chetan Seshadri
Publikováno v:
EBioMedicine, Vol 93, Iss , Pp 104678- (2023)
Summary: Background: The prevalence of tuberculosis among men who work in the gold mines of South Africa is among the highest in the world, but a fraction of miners demonstrate consistently negative results upon tuberculin skin test (TST) and IFN-γ
Externí odkaz:
https://doaj.org/article/0c58ca4c3fba49d19ebee7d80aaf7eba
Autor:
Yannic C. Bartsch, Deniz Cizmeci, Jaewon Kang, Hailong Gao, Wei Shi, Abishek Chandrashekar, Ai-ris Y. Collier, Bing Chen, Dan H. Barouch, Galit Alter
Publikováno v:
iScience, Vol 26, Iss 5, Pp 106582- (2023)
Summary: The number of mutations in the omicron (B.1.1.529) BA.1 variant of concern led to an unprecedented evasion of vaccine induced immunity. However, despite rise in global infections, severe disease did not increase proportionally and is likely
Externí odkaz:
https://doaj.org/article/e7b9dfdebcf3465f9f8e97989e9a0cd6
Autor:
Nadege Nziza, Deniz Cizmeci, Leela Davies, Edward B. Irvine, Wonyeong Jung, Brooke A. Fenderson, Marwou de Kock, Willem A. Hanekom, Kees L. M. C. Franken, Cheryl L. Day, Tom H. M. Ottenhoff, Galit Alter
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Tuberculosis (TB) is among the leading causes of death worldwide from a single infectious agent, second only to COVID-19 in 2020. TB is caused by infection with Mycobacterium tuberculosis (Mtb), that results either in a latent or active form of disea
Externí odkaz:
https://doaj.org/article/c05fb02d0ae946bc9944946fb009224b
Autor:
Stephanie Fischinger, Deniz Cizmeci, Davy Deng, Shannon P Grant, Nicole Frahm, Julie McElrath, Jonathan Fuchs, Pierre-Alexandre Bart, Giuseppe Pantaleo, Michael Keefer, William O Hahn, Nadine Rouphael, Gavin Churchyard, Zoe Moodie, Yeycy Donastorg, Hendrik Streeck, Galit Alter
Publikováno v:
PLoS Pathogens, Vol 17, Iss 11, p e1010016 (2021)
Despite the advent of long-acting anti-retroviral therapy able to control and prevent infection, a preventative vaccine remains a global priority for the elimination of HIV. The moderately protective RV144 vaccine trial suggested functional IgG1 and
Externí odkaz:
https://doaj.org/article/e2e02527435946e8a2d438b49976dfd8
Autor:
Stephanie Fischinger, Deniz Cizmeci, Sally Shin, Leela Davies, Patricia S. Grace, Aida Sivro, Nonhlanhla Yende-Zuma, Hendrik Streeck, Sarah M. Fortune, Douglas A. Lauffenburger, Kogieleum Naidoo, Galit Alter
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
South Africa has the highest prevalence of HIV and tuberculosis (TB) co-infection globally. Recurrent TB, caused by relapse or reinfection, makes up the majority of TB cases in South Africa, and HIV infected individuals have a greater likelihood of d
Externí odkaz:
https://doaj.org/article/8606591427d449929f59cab8b65734f8
Autor:
Deniz Cizmeci, Giuseppe Lofano, Evan Rossignol, Anne-Sophie Dugast, Dongkyoon Kim, Guy Cavet, Ngan Nguyen, Yann Chong Tan, Michael S Seaman, Galit Alter, Boris Julg
Publikováno v:
eLife, Vol 10 (2021)
A minor subset of individuals infected with HIV-1 develop antibody neutralization breadth during the natural course of the infection, often linked to chronic, high-level viremia. Despite significant efforts, vaccination strategies have been unable to
Externí odkaz:
https://doaj.org/article/742b0119745f4f6ba978c07e113f3df9
Autor:
Krystle K.Q. Yu, Stephanie Fischinger, Malisa T. Smith, Caroline Atyeo, Deniz Cizmeci, Caitlin R. Wolf, Erik D. Layton, Jennifer K. Logue, Melissa S. Aguilar, Kiel Shuey, Carolin Loos, Jingyou Yu, Nicholas Franko, Robert Y. Choi, Anna Wald, Dan H. Barouch, David M. Koelle, Douglas Lauffenburger, Helen Y. Chu, Galit Alter, Chetan Seshadri
Publikováno v:
JCI Insight, Vol 6, Iss 6 (2021)
Comorbid medical illnesses, such as obesity and diabetes, are associated with more severe COVID-19, hospitalization, and death. However, the role of the immune system in mediating these clinical outcomes has not been determined. We used multiparamete
Externí odkaz:
https://doaj.org/article/b5959002267547a3b33b4f8d69ee17df