Zobrazeno 1 - 10
of 245
pro vyhledávání: '"Denitsa Docheva"'
Autor:
Honghan Li, Deqing Luo, Wei Xie, Wenbin Ye, Jinlong Chen, Paolo Alberton, Mingzhu Zhang, Eryou Feng, Denitsa Docheva, Dasheng Lin
Publikováno v:
iScience, Vol 27, Iss 11, Pp 111042- (2024)
Summary: Irisin, an exercise-induced myokine, is known to be able to regulate bone metabolism. However, the underlying mechanisms regarding the effects of irisin on senile osteoporosis have not been fully elucidated. Here, we demonstrated that irisin
Externí odkaz:
https://doaj.org/article/d3a6d133583e496fa3d9cedb9be27177
Autor:
Shinsei Yambe, Yuki Yoshimoto, Kazutaka Ikeda, Koichiro Maki, Aki Takimoto, Akihide Tokuyama, Shinnosuke Higuchi, Xinyi Yu, Kenta Uchibe, Shigenori Miura, Hitomi Watanabe, Tetsushi Sakuma, Takashi Yamamoto, Kotaro Tanimoto, Gen Kondoh, Masataka Kasahara, Toshihide Mizoguchi, Denitsa Docheva, Taiji Adachi, Chisa Shukunami
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Fibrocartilaginous entheses consist of tendons, unmineralized and mineralized fibrocartilage, and subchondral bone, each exhibiting varying stiffness. Here we examined the functional role of sclerostin, expressed in mature mineralized fibrochondrocyt
Externí odkaz:
https://doaj.org/article/427052bd41564fbcaaa067f05c89e21b
Autor:
Alfredo Ronca, Ugo D'Amora, Elisa Capuana, Carla Zihlmann, Niklaus Stiefel, Girish Pattappa, Ruth Schewior, Denitsa Docheva, Peter Angele, Luigi Ambrosio
Publikováno v:
Heliyon, Vol 10, Iss 3, Pp e25286- (2024)
Externí odkaz:
https://doaj.org/article/b0fcd545f2624ac287728eca5002f6bd
Autor:
Alfredo Ronca, Ugo D'Amora, Elisa Capuana, Carla Zihlmann, Niklaus Stiefel, Girish Pattappa, Ruth Schewior, Denitsa Docheva, Peter Angele, Luigi Ambrosio
Publikováno v:
Heliyon, Vol 9, Iss 12, Pp e23107- (2023)
The most prevalent extracellular matrix (ECM) protein in the meniscus is collagen, which controls cell activity and aids in preserving the biological and structural integrity of the ECM. To create stable and high-precision 3D printed collagen scaffol
Externí odkaz:
https://doaj.org/article/f81dfa4c461a45df9d74b79201ddaff7
Autor:
Gundula G. Schulze-Tanzil, Manuel Delgado Cáceres, Richard Stange, Britt Wildemann, Denitsa Docheva
Publikováno v:
Bone & Joint Research, Vol 11, Iss 8, Pp 561-574 (2022)
Tendon is a bradytrophic and hypovascular tissue, hence, healing remains a major challenge. The molecular key events involved in successful repair have to be unravelled to develop novel strategies that reduce the risk of unfavourable outcomes such as
Externí odkaz:
https://doaj.org/article/bc8a6ad1e9eb44c38ea8f4c38eeeb952
Autor:
Francisca I. Alagboso, Gopala K. Mannala, Nike Walter, Denitsa Docheva, Christoph Brochhausen, Volker Alt, Markus Rupp
Publikováno v:
Bone & Joint Research, Vol 11, Iss 5, Pp 327-341 (2022)
Aims: Bone regeneration during treatment of staphylococcal bone infection is challenging due to the ability of Staphylococcus aureus to invade and persist within osteoblasts. Here, we sought to determine whether the metabolic and extracellular organi
Externí odkaz:
https://doaj.org/article/fd666b69e3db4d1eb3f0fd458022d918
Autor:
Manuel Delgado Caceres, Katharina Angerpointner, Michael Galler, Dasheng Lin, Philipp A. Michel, Christoph Brochhausen, Xin Lu, Adithi R. Varadarajan, Jens Warfsmann, Richard Stange, Volker Alt, Christian G. Pfeifer, Denitsa Docheva
Publikováno v:
Cell Death and Disease, Vol 12, Iss 11, Pp 1-13 (2021)
Abstract Heterotopic ossification (HO) represents a common problem after tendon injury with no effective treatment yet being developed. Tenomodulin (Tnmd), the best-known mature marker for tendon lineage cells, has important effects in tendon tissue
Externí odkaz:
https://doaj.org/article/9c34c922da0345759afc57f0147bba83
Autor:
Henning Madry, Susanne Grässel, Ulrich Nöth, Borna Relja, Anke Bernstein, Denitsa Docheva, Max Daniel Kauther, Jan Christoph Katthagen, Rainer Bader, Martijn van Griensven, Dieter C. Wirtz, Michael J. Raschke, Markus Huber-Lang
Publikováno v:
European Journal of Medical Research, Vol 26, Iss 1, Pp 1-16 (2021)
Abstract Orthopaedic and trauma research is a gateway to better health and mobility, reflecting the ever-increasing and complex burden of musculoskeletal diseases and injuries in Germany, Europe and worldwide. Basic science in orthopaedics and trauma
Externí odkaz:
https://doaj.org/article/3e67ae34cc8646db8aa6816d8ec87fc6
Autor:
Niklas Kroner-Weigl, Jin Chu, Maximilian Rudert, Volker Alt, Chisa Shukunami, Denitsa Docheva
Publikováno v:
Biomedicines, Vol 11, Iss 3, p 772 (2023)
Self-assembling three-dimensional organoids that do not rely on an exogenous scaffold but maintain their native cell-to-cell and cell-to-matrix interactions represent a promising model in the field of tendon tissue engineering. We have identified der
Externí odkaz:
https://doaj.org/article/50ec4cd03730492483f99e0d035db7a3
Publikováno v:
Bioengineering & Translational Medicine, Vol 7, Iss 1, Pp n/a-n/a (2022)
Abstract Titanium is commonly and successfully used in dental and orthopedic implants. However, patients still have to face the risk of implant failure due to various reasons, such as implant loosening or infection. The risk of implant loosening can
Externí odkaz:
https://doaj.org/article/5bfc36652be74fd1abd02f70f98d8a6a