Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Denitsa Aluani"'
Autor:
Denitsa Aluani, Magdalena Kondeva-Burdina, Alexandra Tosheva, Krassimira Yoncheva, Virginia Tzankova
Publikováno v:
Pharmacia, Vol 69, Iss 1, Pp 25-29 (2022)
Antioxidant capacity of poorly soluble natural antioxidant kaempferol, in particular free or loaded in two types of cationic micelles, was studied on non-enzyme induced lipid peroxidation (LPO) in vitro. The micelles were based on triblock copolymers
Externí odkaz:
https://doaj.org/article/9ff20bd9c0424c1fa401be61aa2cd0bf
Publikováno v:
Pharmacia, Vol 68, Iss 3, Pp 657-664 (2021)
A modified UHPLC-HRMS method for simultaneous quantification of eight flavonoids from the aerial parts of the wild spinach (Chenopodium bonus-henricus L.) was re-validated for specificity, the limit of detection and quantitation limit, linearity, acc
Externí odkaz:
https://doaj.org/article/7211dc92e0494aa6b7ce0664740373e1
Autor:
Neda Anastassova, Denitsa Aluani, Anton Kostadinov, Miroslav Rangelov, Nadezhda Todorova, Nadya Hristova-Avakumova, Maria Argirova, Nikolay Lumov, Magdalena Kondeva-Burdina, Virginia Tzankova, Denitsa Yancheva
Publikováno v:
Neural Regeneration Research, Vol 16, Iss 11, Pp 2299-2309 (2021)
Neuroprotective drugs and selective monoamine oxidase inhibitors can slow down the progression and improve symptoms of Parkinson’s disease (PD). Since there is an implication of oxidative stress in the pathophysiological mechanisms of the disease,
Externí odkaz:
https://doaj.org/article/1e52033895d44df3a1a4c0635ecec6da
Autor:
Rositsa Mihaylova, Aleksandar Shkondrov, Denitsa Aluani, Iliana Ionkova, Virginia Tzankova, Ilina Krasteva
Publikováno v:
Biotechnology & Biotechnological Equipment, Vol 35, Iss 1, Pp 1948-1955 (2021)
Many species of genus Astragalus have been extensively studied for their wide range of biological activities, including antioxidant, cytoprotective, anti-inflammatory, antitumour, anti-infective, immune-boosting, antihypertensive and antidiabetic eff
Externí odkaz:
https://doaj.org/article/831d1e98636f4b1b944384ca51e3d8e6
Autor:
Petko Alov, Merilin Al Sharif, Denitsa Aluani, Konstantin Chegaev, Jelena Dinic, Aleksandra Divac Rankov, Miguel X. Fernandes, Fabio Fusi, Alfonso T. García-Sosa, Risto Juvonen, Magdalena Kondeva-Burdina, José M. Padrón, Ilza Pajeva, Tania Pencheva, Adrián Puerta, Hannu Raunio, Chiara Riganti, Ivanka Tsakovska, Virginia Tzankova, Yordan Yordanov, Simona Saponara
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Sdox is a hydrogen sulfide (H2S)-releasing doxorubicin effective in P-glycoprotein-overexpressing/doxorubicin-resistant tumor models and not cytotoxic, as the parental drug, in H9c2 cardiomyocytes. The aim of this study was the assessment of Sdox dru
Externí odkaz:
https://doaj.org/article/1c7deddbd8504d1eb6e324f730103fb1
Autor:
Borislav Tzankov, Christina Voycheva, Yordan Yordanov, Denitsa Aluani, Ivanka Spassova, Daniela Kovacheva, Nikolay Lambov, Virginia Tzankova
Publikováno v:
Biotechnology & Biotechnological Equipment, Vol 33, Iss 1, Pp 1204-1215 (2019)
In this study, spherical hollow mesoporous silica (HMS) particles with average size of 550 nm were loaded with dopamine-receptor agonist pramipexole, as a model drug. High drug loading (55%) was achieved by its incorporation in the reservoir structur
Externí odkaz:
https://doaj.org/article/8876b67004e744daa25ba39447fe447d
Autor:
Krassimira Yoncheva, Virginia Tzankova, Yordan Yordanov, Borislav Tzankov, Georgy Grancharov, Denitsa Aluani, Vassya Bankova, Milena Popova, Boryana Trusheva, Magdalena Kondeva-Burdina, Petar Petrov
Publikováno v:
Biotechnology & Biotechnological Equipment, Vol 33, Iss 1, Pp 64-74 (2019)
Caffeic acid phenethyl ester (CAPE), a hydrophobic constituent of poplar propolis of valuable biological activity, was immobilized in poly(ethylene oxide)-b-poly(ε-caprolactone)-b-poly(ethylene oxide) (PEO-b-PCL-b-PEO) copolymer micelles to improve
Externí odkaz:
https://doaj.org/article/764a47261e0647949c020fc4acd6f87b
Autor:
Neda Anastassova, Denitsa Aluani, Nadya Hristova-Avakumova, Virginia Tzankova, Magdalena Kondeva-Burdina, Miroslav Rangelov, Nadezhda Todorova, Denitsa Yancheva
Publikováno v:
Antioxidants, Vol 11, Iss 5, p 884 (2022)
Oxidative stress is a key contributing factor in the complex degenerating cascade in Parkinson’s disease. The inhibition of MAO-B affords higher dopamine bioavailability and stops ROS formation. The incorporation of hydroxy and methoxy groups in th
Externí odkaz:
https://doaj.org/article/d8cc020f24064f3db2fd14a50b77e549
Autor:
Denitsa Aluani, Virginia Tzankova, Yordan Yordanov, Magdalena Kondeva-Burdina, Krassimira Yoncheva
Publikováno v:
Biotechnology & Biotechnological Equipment, Vol 31, Iss 5, Pp 1055-1063 (2017)
The aim of the present study was to evaluate the protective effects of free and encapsulated quercetin against oxidative stress injury in neuronal SH-SY5Y cells and isolated rat brain synaptosomes. Quercetin (QR) was encapsulated in nanoparticles con
Externí odkaz:
https://doaj.org/article/8f799e87ad424494a9762b7af6c5a553
Autor:
Cvetelina Gorinova, Denitsa Aluani, Yordan Yordanov, Magdalena Kondeva-Burdina, Virginia Tzankova, Cvetelina Popova, Krassimira Yoncheva
Publikováno v:
Biotechnology & Biotechnological Equipment, Vol 30, Iss 5, Pp 991-997 (2016)
Curcumin is a polyphenolic substance with attractive pharmacological activities (e.g. antioxidant, anti-inflammatory, anticancer). Incorporation of curcumin in polymeric micelles could overcome the problems associated with its instability and low aqu
Externí odkaz:
https://doaj.org/article/382dd1f4701a48cf9843796cbe0ddab8