Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Denitsa, Momekova"'
Publikováno v:
Pharmacia, Vol 71, Iss , Pp 1-8 (2024)
Vesicular carriers are a well-established approach to improving the technological and biopharmaceutical characteristics of the loaded cargo. The current manuscript is focused on the development and evaluation in a comparative aspect of two types of v
Externí odkaz:
https://doaj.org/article/0eabe8e8c8234cd48cfa5d66415e5996
Autor:
Viliana Gugleva, Katerina Ahchiyska, Dilyana Georgieva, Rositsa Mihaylova, Spiro Konstantinov, Erik Dimitrov, Natalia Toncheva-Moncheva, Stanislav Rangelov, Aleksander Forys, Barbara Trzebicka, Denitsa Momekova
Publikováno v:
Pharmaceutics, Vol 15, Iss 10, p 2414 (2023)
Cannabidiol (CBD) is a promising drug candidate with pleiotropic pharmacological activity, whose low aqueous solubility and unfavorable pharmacokinetics have presented obstacles to its full clinical implementation. The rational design of nanocarriers
Externí odkaz:
https://doaj.org/article/8a345125d311436e91da42b4710e0722
Autor:
Anife Ahmedova, Rositsa Mihaylova, Silviya Stoykova, Veronika Mihaylova, Nikola Burdzhiev, Viktoria Elincheva, Georgi Momekov, Denitsa Momekova
Publikováno v:
Pharmaceutics, Vol 15, Iss 9, p 2310 (2023)
Research on platinum-based anticancer drugs continuously strives to develop new non-classical platinum complexes. Pt(IV) prodrugs are the most promising, and their activation-by-reduction mechanism of action is being explored as a prospect for higher
Externí odkaz:
https://doaj.org/article/0337ffa9a33941b099cc117e50374d9b
Autor:
Natalia Toncheva-Moncheva, Erik Dimitrov, Georgi Grancharov, Denitsa Momekova, Petar Petrov, Stanislav Rangelov
Publikováno v:
Pharmaceutics, Vol 15, Iss 8, p 2128 (2023)
The present study describes the development of novel block copolymer nanocarriers of the phytocannabinoid cannabidiol (CBD), designed to enhance the solubility of the drug in water while achieving high encapsulation efficiency and prolonged drug rele
Externí odkaz:
https://doaj.org/article/2c3f1c2cbb3f487188b7f83c320759ee
Publikováno v:
Plants, Vol 12, Iss 15, p 2795 (2023)
This study aimed to analyze the composition of grape seed oil (GSO) derived from an alternative source after traditional fermentation processes and its potential anti-inflammatory effects using an in vivo model of carrageenan-induced inflammation in
Externí odkaz:
https://doaj.org/article/acd85fb67ce24fffaa8d7ef408640d4a
Publikováno v:
Pharmaceuticals, Vol 16, Iss 7, p 938 (2023)
This review paper is focused on the design of anthracene and furan-containing Schiff bases and their advanced properties as ligands in complex transition metal ions The paper also provides a brief overview on a variety of biological applications, nam
Externí odkaz:
https://doaj.org/article/f0d361551d9a4f9b80b428d62ecf019a
Autor:
Maria Schröder, Maria Petrova, Georgi M. Dobrikov, Georgy Grancharov, Denitsa Momekova, Petar D. Petrov, Iva Ugrinova
Publikováno v:
Pharmaceutics, Vol 15, Iss 3, p 791 (2023)
The discovery of new anticancer drugs with а higher, more specific activity and diminished side effects than the conventional chemotherapeutic agents is a tremendous challenge to contemporary medical research and development. To achieve a pronounced
Externí odkaz:
https://doaj.org/article/262cfa7c7cf64137b0dd1ba4daf23c67
Autor:
Georgi Momekov, Denitsa Momekova
Publikováno v:
Biotechnology & Biotechnological Equipment, Vol 34, Iss 1, Pp 469-474 (2020)
The broad-spectrum antiparasitic agent ivermectin has been very recently found to inhibit SARS-CoV-2 in vitro and proposed as a candidate for drug repurposing in COVID-19. In the present report the in vitro antiviral activity end-points are analyzed
Externí odkaz:
https://doaj.org/article/8bf3c5c416be474e9f49d174dabf0f61
Autor:
Ivalina Trendafilova, Ralitsa Chimshirova, Denitsa Momekova, Hristo Petkov, Neli Koseva, Penka Petrova, Margarita Popova
Publikováno v:
Nanomaterials, Vol 12, Iss 17, p 3075 (2022)
Biologically active substances of natural origin offer a promising alternative in skin disease treatment in comparison to synthetic medications. The limiting factors for the efficient application of natural compounds, such as low water solubility and
Externí odkaz:
https://doaj.org/article/61d4ec010f1e4e55a8aa763c3fc86465
Autor:
Viliana Gugleva, Victoria Michailova, Rositsa Mihaylova, Georgi Momekov, Maya Margaritova Zaharieva, Hristo Najdenski, Petar Petrov, Stanislav Rangelov, Aleksander Forys, Barbara Trzebicka, Denitsa Momekova
Publikováno v:
Pharmaceutics, Vol 14, Iss 4, p 747 (2022)
The current study describes the elaboration of a hybrid drug delivery platform for an intravesical application based on curcumin/gentamicin sulfate simultaneously loaded niosomes incorporated into thermosensitive in situ gels. Series of niosomes were
Externí odkaz:
https://doaj.org/article/f3a14ac2d7ab4122ae57426b8178a9a3