Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Denitra Breuer"'
Autor:
Mareca Lodge, Grace Scheidemantle, Victoria R. Adams, Matthew A. Cottam, Daniel Richard, Denitra Breuer, Peter Thompson, Kritika Shrestha, Xiaojing Liu, Arion Kennedy
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Over-consumption of fructose in adults and children has been linked to increased risk of non-alcoholic fatty liver disease (NAFLD). Recent studies have highlighted the effect of fructose on liver inflammation, fibrosis, and immune cell activ
Externí odkaz:
https://doaj.org/article/883963a7742a4c109a9f2b0797ddf793
Autor:
Ryan M. Schuchman, Ricardo Vancini, Amanda Piper, Denitra Breuer, Mariana Ribeiro, Davis Ferreira, Joseph Magliocca, Veronica Emmerich, Raquel Hernandez, Dennis T. Brown
Publikováno v:
Heliyon, Vol 4, Iss 7, Pp e00701- (2018)
We have shown that Alphaviruses can enter cells by direct penetration at the plasma membrane (R. Vancini, G. Wang, D. Ferreira, R. Hernandez, and D. Brown, J Virol, 87:4352–4359, 2013). Direct penetration removes the requirement for receptor-mediat
Externí odkaz:
https://doaj.org/article/f6f43992cf2e4c0ea085856c28e65987
Autor:
Tatiana Ammosova, Yuri Obukhov, Alexander Kotelkin, Denitra Breuer, Monique Beullens, Victor R Gordeuk, Mathieu Bollen, Sergei Nekhai
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18985 (2011)
The cyclin-dependent kinase CDK9/cyclin T1 induces HIV-1 transcription by phosphorylating the carboxyterminal domain (CTD) of RNA polymerase II (RNAPII). CDK9 activity is regulated by protein phosphatase-1 (PP1) which was previously shown to dephosph
Externí odkaz:
https://doaj.org/article/2edfb43687bb43d09555f553a9698b3d
Autor:
Denitra Breuer, Maria Cristina Pacheco, M. Kay Washington, Stephanie A. Montgomery, Arion Kennedy, Alyssa H. Hasty
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 318:G211-G224
Nonalcoholic steatohepatitis (NASH) has increased in Western countries due to the prevalence of obesity. Current interests are aimed at identifying the type and function of immune cells that infiltrate the liver and key factors responsible for mediat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23f485485c8b8723c86e8ebba3737e9b
https://doi.org/10.1152/ajpgi.00040.2019
https://doi.org/10.1152/ajpgi.00040.2019
Autor:
Peter M. Thompson, Xiaojing Liu, Arion Kennedy, Mareca Lodge, Denitra Breuer, Grace Scheidemantle
Publikováno v:
Curr Dev Nutr
OBJECTIVES: Recently fructose has been linked to the development of Nonalcoholic Fatty Liver Disease (NAFLD), but the mechanisms behind the progression remain to be elucidated. Kupffer cells have been identified as regulators of hepatic inflammation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9432451895eaa331f7ab3c63f951c9a2
https://europepmc.org/articles/PMC7259299/
https://europepmc.org/articles/PMC7259299/
Autor:
Dmytro Kovalskyy, Fatah Kashanchi, Sergey Iordanskiy, Konstantin S. Gavrilenko, Sergei Nekhai, Xiaomei Niu, Subhash Dhawan, Denitra Breuer, Xionghao Lin, Namita Kumari, Min Xu
Publikováno v:
Antimicrobial Agents and Chemotherapy. 58:6558-6571
HIV-1 transcription is activated by the Tat protein, which recruits CDK9/cyclin T1 to the HIV-1 promoter. CDK9 is phosphorylated by CDK2, which facilitates formation of the high-molecular-weight positive transcription elongation factor b (P-TEFb) com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a9f93df732d9865abe2ea372c7db785
https://doi.org/10.1128/aac.02918-14
https://doi.org/10.1128/aac.02918-14
Autor:
Des R. Richardson, Denitra Breuer, Marina Jerebtsova, Krishna Kumar, Danuta S. Kalinowski, Victor R. Gordeuk, David B. Lovejoy, Tatyana Ammosova, Patricio E. Ray, Sergei Nekhai, Zufan Debebe, Fatah Kashanchi, Pradeep K. Karla
Publikováno v:
Molecular Pharmacology. 79:185-196
HIV-1 transcription is activated by HIV-1 Tat protein, which recruits cyclin-dependent kinase 9 (CDK9)/cyclin T1 and other host transcriptional coactivators to the HIV-1 promoter. Tat itself is phosphorylated by CDK2, and inhibition of CDK2 by small
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40cc1ada101db43e1adb8f37d8a91910
https://doi.org/10.1124/mol.110.069062
https://doi.org/10.1124/mol.110.069062
Autor:
Davis Fernandes Ferreira, Ricardo Vancini, Ryan M. Schuchman, Raquel Hernandez, Mariana Ribeiro, Amanda Piper, Veronica Emmerich, Denitra Breuer, Joseph Magliocca, Dennis Brown
Publikováno v:
Heliyon
Heliyon, Vol 4, Iss 7, Pp e00701-(2018)
Heliyon, Vol 4, Iss 7, Pp e00701-(2018)
We have shown that Alphaviruses can enter cells by direct penetration at the plasma membrane (R. Vancini, G. Wang, D. Ferreira, R. Hernandez, and D. Brown, J Virol, 87:4352–4359, 2013). Direct penetration removes the requirement for receptor-mediat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5e404fc56f4b4afd8df3cad2be0422f
https://doi.org/10.1016/j.heliyon.2018.e00701
https://doi.org/10.1016/j.heliyon.2018.e00701
Autor:
Namita Kumari, Yasemin Saygideger Kont, Kahli A. Smith, Aykut Üren, Sergei Nekhai, Andrey V. Ilatovskiy, Michael Petukhov, Mudit Tyagi, Sergey Iordanskiy, Tatyana Ammosova, Dmytro Kovalskyy, Andrey Ivanov, Denitra Breuer, Fatah Kashanchi
Publikováno v:
Retrovirology
Background HIV-1 escapes antiretroviral drugs by integrating into the host DNA and forming a latent transcriptionally silent HIV-1 provirus. This provirus presents the major hurdle in HIV-1 eradication and cure. Transcriptional activation, which is p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71e88a2af45de9b6731ab566080c58c5
https://doi.org/10.1186/s12977-015-0190-4
https://doi.org/10.1186/s12977-015-0190-4
Publikováno v:
BioMed Research International, Vol 2014 (2014)
BioMed Research International
BioMed Research International
HIV-1 transcription is regulated by CDK9/cyclin T1, which, unlike a typical cell cycle-dependent kinase, is regulated by associating with 7SK small nuclear ribonuclear protein complex (snRNP). While the protein components of this complex are well stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0be9875788fcfd6b0fe1f691af5d925b
https://doaj.org/article/dc8b6fbfc3f342b69eeb4bc146529e2e
https://doaj.org/article/dc8b6fbfc3f342b69eeb4bc146529e2e