Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Denisse A. Gutierrez"'
Autor:
Edgar A. Borrego, Cristina D. Guerena, Austre Y. Schiaffino Bustamante, Denisse A. Gutierrez, Carlos A. Valenzuela, Ana P. Betancourt, Armando Varela-Ramirez, Renato J. Aguilera
Publikováno v:
Cells, Vol 13, Iss 14, p 1225 (2024)
In this study, we screened a chemical library to find potent anticancer compounds that are less cytotoxic to non-cancerous cells. This study revealed that pyrazole PTA-1 is a potent anticancer compound. Additionally, we sought to elucidate its mechan
Externí odkaz:
https://doaj.org/article/97f5151a9dd4484494b956ab042815b1
Autor:
Jessica D. Hess, Luca H. Macias, Denisse A. Gutierrez, Karla Moran-Santibanez, Lisett Contreras, Stephanie Medina, Paulina J. Villanueva, Robert A. Kirken, Armando Varela-Ramirez, Manuel L. Penichet, Renato J. Aguilera
Publikováno v:
Biology, Vol 11, Iss 6, p 930 (2022)
In recent years, the thienopyrazole moiety has emerged as a pharmacologically active scaffold with antitumoral and kinase inhibitory activity. In this study, high-throughput screening of 2000 small molecules obtained from the ChemBridge DIVERset libr
Externí odkaz:
https://doaj.org/article/ecd0ac3c2f914b6c81921427813e37b2
Autor:
Denisse A. Gutierrez, Lisett Contreras, Paulina J. Villanueva, Edgar A. Borrego, Karla Morán-Santibañez, Jessica D. Hess, Rebecca DeJesus, Manuel Larragoity, Ana P. Betancourt, Jonathon E. Mohl, Elisa Robles-Escajeda, Khodeza Begum, Sourav Roy, Robert A. Kirken, Armando Varela-Ramirez, Renato J. Aguilera
Publikováno v:
Cells, Vol 11, Iss 2, p 254 (2022)
In this study, we identified a novel pyrazole-based derivative (P3C) that displayed potent cytotoxicity against 27 human cancer cell lines derived from different tissue origins with 50% cytotoxic concentrations (CC50) in the low micromolar and nanomo
Externí odkaz:
https://doaj.org/article/5cbd8028ab8145fe8e7fc335095f7d64
Autor:
Aleli Campbell, Jonathon E. Mohl, Denisse A. Gutierrez, Armando Varela-Ramirez, Thomas Boland
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Bioprinting technology merges engineering and biological fields and together, they possess a great translational potential, which can tremendously impact the future of regenerative medicine and drug discovery. However, the molecular effects elicited
Externí odkaz:
https://doaj.org/article/9d4e3db883c14cfe8a37f93c18bcad5b
Autor:
Aleli Campbell, Denisse A. Gutierrez, Colin Knight, Charlotte M. Vines, Rosalinda Heydarian, Alexander Philipovskiy, Armando Varela-Ramirez, Thomas Boland
Publikováno v:
Materials, Vol 14, Iss 24, p 7864 (2021)
Background: Breast cancer (BC) continues to have the second highest mortality amongst women in the United States after lung cancer. For 2021, the American Cancer Association predicted 281,550 new invasive breast cancer cases besides 49,290 new cases
Externí odkaz:
https://doaj.org/article/6acf389ebe584de7b4b53c60ea810330
Autor:
Bianca P. Meneses-Brassea, Edgar A. Borrego, Dawn S. Blazer, Mohamed F. Sanad, Shirin Pourmiri, Denisse A. Gutierrez, Armando Varela-Ramirez, George C. Hadjipanayis, Ahmed A. El-Gendy
Publikováno v:
Nanomaterials, Vol 10, Iss 10, p 1988 (2020)
Ni-Cu nanoparticles have been synthesized by reducing Ni and Cu from metal precursors using a sol–gel route followed by annealing at 300 °C for 1, 2, 3, 6, 8, and 10 h for controlled self-regulating magnetic hyperthermia applications. Particle mor
Externí odkaz:
https://doaj.org/article/4e9e8e8deadb4d68a9e1be86dbfcf667
Publikováno v:
Journal of Toxicology, Vol 2020 (2020)
Journal of Toxicology
Journal of Toxicology
Combustion-derived nanomaterials are noxious ultrafine (
Autor:
Denisse A. Gutierrez, Paulina J. Villanueva, Lisett Contreras, Karla Parra, Armando Varela-Ramirez, Renato J. Aguilera, Giulio Francia, Aldo Segura-Cabrera
Publikováno v:
Clin Cancer Drugs
Background: Breast cancer is the most frequently diagnosed cancer in women worldwide. Pyronaridine (PND), an antimalarial drug, was shown to exert anticancer activity on seventeen different human cancer cells, seven from female breast tissue. Additio
Autor:
Renato J. Aguilera, Denisse A. Gutierrez, Filip Fratev, Chendil Damodaran, Suman Sirimulla, Ashish Tyagi
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 39:368-377
Autor:
Jessica D. Hess, Denisse A. Gutierrez, Renato J. Aguilera, Luca Henze, Armando Varela-Ramirez
Publikováno v:
The FASEB Journal. 35