Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Denisse A. Gutierrez"'
Autor:
Edgar A. Borrego, Cristina D. Guerena, Austre Y. Schiaffino Bustamante, Denisse A. Gutierrez, Carlos A. Valenzuela, Ana P. Betancourt, Armando Varela-Ramirez, Renato J. Aguilera
Publikováno v:
Cells, Vol 13, Iss 14, p 1225 (2024)
In this study, we screened a chemical library to find potent anticancer compounds that are less cytotoxic to non-cancerous cells. This study revealed that pyrazole PTA-1 is a potent anticancer compound. Additionally, we sought to elucidate its mechan
Externí odkaz:
https://doaj.org/article/97f5151a9dd4484494b956ab042815b1
Autor:
Jessica D. Hess, Luca H. Macias, Denisse A. Gutierrez, Karla Moran-Santibanez, Lisett Contreras, Stephanie Medina, Paulina J. Villanueva, Robert A. Kirken, Armando Varela-Ramirez, Manuel L. Penichet, Renato J. Aguilera
Publikováno v:
Biology, Vol 11, Iss 6, p 930 (2022)
In recent years, the thienopyrazole moiety has emerged as a pharmacologically active scaffold with antitumoral and kinase inhibitory activity. In this study, high-throughput screening of 2000 small molecules obtained from the ChemBridge DIVERset libr
Externí odkaz:
https://doaj.org/article/ecd0ac3c2f914b6c81921427813e37b2
Autor:
Aleli Campbell, Jonathon E. Mohl, Denisse A. Gutierrez, Armando Varela-Ramirez, Thomas Boland
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Bioprinting technology merges engineering and biological fields and together, they possess a great translational potential, which can tremendously impact the future of regenerative medicine and drug discovery. However, the molecular effects elicited
Externí odkaz:
https://doaj.org/article/9d4e3db883c14cfe8a37f93c18bcad5b
Autor:
Denisse A. Gutierrez, Lisett Contreras, Paulina J. Villanueva, Edgar A. Borrego, Karla Morán-Santibañez, Jessica D. Hess, Rebecca DeJesus, Manuel Larragoity, Ana P. Betancourt, Jonathon E. Mohl, Elisa Robles-Escajeda, Khodeza Begum, Sourav Roy, Robert A. Kirken, Armando Varela-Ramirez, Renato J. Aguilera
Publikováno v:
Cells, Vol 11, Iss 2, p 254 (2022)
In this study, we identified a novel pyrazole-based derivative (P3C) that displayed potent cytotoxicity against 27 human cancer cell lines derived from different tissue origins with 50% cytotoxic concentrations (CC50) in the low micromolar and nanomo
Externí odkaz:
https://doaj.org/article/5cbd8028ab8145fe8e7fc335095f7d64
Autor:
Bianca P. Meneses-Brassea, Edgar A. Borrego, Dawn S. Blazer, Mohamed F. Sanad, Shirin Pourmiri, Denisse A. Gutierrez, Armando Varela-Ramirez, George C. Hadjipanayis, Ahmed A. El-Gendy
Publikováno v:
Nanomaterials, Vol 10, Iss 10, p 1988 (2020)
Ni-Cu nanoparticles have been synthesized by reducing Ni and Cu from metal precursors using a sol–gel route followed by annealing at 300 °C for 1, 2, 3, 6, 8, and 10 h for controlled self-regulating magnetic hyperthermia applications. Particle mor
Externí odkaz:
https://doaj.org/article/4e9e8e8deadb4d68a9e1be86dbfcf667
Publikováno v:
Journal of Toxicology, Vol 2020 (2020)
Journal of Toxicology
Journal of Toxicology
Combustion-derived nanomaterials are noxious ultrafine (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03d6bddad377320ac662ac33401c3d38
https://doi.org/10.1155/2020/5702024
https://doi.org/10.1155/2020/5702024
Autor:
Renato J. Aguilera, Denisse A. Gutierrez, Filip Fratev, Chendil Damodaran, Suman Sirimulla, Ashish Tyagi
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 39:368-377
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0dc3f046dd4cb93ebcf1e90e40848cd3
https://doi.org/10.1080/07391102.2020.1715835
https://doi.org/10.1080/07391102.2020.1715835
Autor:
Denisse A. Gutierrez, Paulina J. Villanueva, Lisett Contreras, Karla Parra, Armando Varela-Ramirez, Renato J. Aguilera, Giulio Francia, Aldo Segura-Cabrera
Publikováno v:
Clin Cancer Drugs
Background: Breast cancer is the most frequently diagnosed cancer in women worldwide. Pyronaridine (PND), an antimalarial drug, was shown to exert anticancer activity on seventeen different human cancer cells, seven from female breast tissue. Additio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56cb98f13d3eff4f84b3b5c3608e6a81
https://pubmed.ncbi.nlm.nih.gov/35178342
https://pubmed.ncbi.nlm.nih.gov/35178342
Autor:
Aleli Campbell, Denisse A. Gutierrez, Colin Knight, Charlotte M. Vines, Rosalinda Heydarian, Alexander Philipovskiy, Armando Varela-Ramirez, Thomas Boland
Publikováno v:
Materials
Materials; Volume 14; Issue 24; Pages: 7864
Materials, Vol 14, Iss 7864, p 7864 (2021)
Materials; Volume 14; Issue 24; Pages: 7864
Materials, Vol 14, Iss 7864, p 7864 (2021)
Background: Breast cancer (BC) continues to have the second highest mortality amongst women in the United States after lung cancer. For 2021, the American Cancer Association predicted 281,550 new invasive breast cancer cases besides 49,290 new cases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3de38d7ec28a385d8dc4c3f589f83a7
http://europepmc.org/articles/PMC8704911
http://europepmc.org/articles/PMC8704911
Autor:
Denisse A. Gutierrez, Edward A. Espinoza-Sánchez, Tania Siqueiros-Cendón, Quintín Rascón-Cruz, Blanca F. Iglesias-Figueroa, Sigifredo Arévalo-Gallegos, Armando Varela-Ramirez, Renato J. Aguilera
Publikováno v:
Apoptosis
Breast cancer is the most frequently diagnosed cancer among women worldwide. Here, recombinant human lactoferrin (rhLf) expressed in Pichia pastoris was tested for its potential cytotoxic activity on a panel of six human breast cancer cell lines. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94639560e63aff31e94ca70bca38cc51
https://doi.org/10.1007/s10495-019-01539-7
https://doi.org/10.1007/s10495-019-01539-7