Výsledky vyhledávání - "Denish Bardoliwala"

Formulation and clinical perspectives of inhalation-based nanocarrier delivery: a new archetype in lung cancer treatment

Autor: Krutika K. Sawant, Saikat Ghosh, Denish Bardoliwala, Ankit Javia, Ambikanandan Misra

Publikováno v: Therapeutic Delivery. 12:397-418

Despite tremendous research in targeted delivery and specific molecular inhibitors (gene delivery), cytotoxic drug delivery through inhalation has been seen as a core part in the treatment of the lung cancer. Inhalation delivery provides a high dose

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3814d6cdc222782c9fcb72491b26e0c1
https://doi.org/10.4155/tde-2020-0101

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Co-delivery of cisplatin and siRNA through hybrid nanocarrier platform for masking resistance to chemotherapy in lung cancer

Autor: Akanksha Patel, Saikat Ghosh, Rohan Lalani, Imran Vhora, Ambikanandan Misra, Denish Bardoliwala, Vivek Patel

Publikováno v: Drug Delivery and Translational Research. 11:2052-2071

The resistance of cancer cells to chemotherapy has presented a formidable challenge. The current research aims at evaluating whether silencing of the cisplatin efflux promoter gene ABCC3 using siRNA co-loaded with the drug in a nanocarrier improves i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::72f550ec7454f618ddab206c44de6129
https://doi.org/10.1007/s13346-020-00867-5

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Development of a dry powder for inhalation of nanoparticles codelivering cisplatin and

Autor: Vivek, Patel, Denish, Bardoliwala, Rohan, Lalani, Sushilkumar, Patil, Saikat, Ghosh, Ankit, Javia, Ambikanandan, Misra

Publikováno v: Therapeutic delivery. 12(9)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::460fe279eb72695928dacc47547de993
https://pubmed.ncbi.nlm.nih.gov/34374565

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Nanocarriers in effective pulmonary delivery of siRNA: current approaches and challenges

Autor: Ambikanandan Misra, Akanksha Patel, Vivek Patel, Ankit Javia, Denish Bardoliwala, Saikat Ghosh

Publikováno v: Therapeutic Delivery. 10:311-332

Research on siRNA is increasing due to its wide applicability as a therapeutic agent in irreversible medical conditions. siRNA inhibits expression of the specific gene after its delivery from formulation to cytosol region of a cell. RNAi (RNA interfe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3bfff126cdc5749eb3912088cf1d527
https://doi.org/10.4155/tde-2019-0012

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Combinatorial nanocarriers against drug resistance in hematological cancers: Opportunities and emerging strategies

Autor: Vivek Patel, Subhas Balaram Bhowmick, Rohan Lalani, Shubhadeep Banerjee, Denish Bardoliwala, Saikat Ghosh, Kuntal Maiti, Ambikanandan Misra

Publikováno v: Journal of Controlled Release. 296:114-139

Hematological cancers are a group of malignancies affecting human hematopoietic and lymphoid tissues. Although the patients respond to treatment regimen during initial phases, the hematoma tumor heterogeneity results in the presence of some minimal d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0797eea0e49815c01d2c72149f0c3578
https://doi.org/10.1016/j.jconrel.2019.01.011

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Polymer-drug conjugates: Design principles, emerging synthetic strategies and clinical overview

Autor: Ankit Javia, Jigar Vanza, Denish Bardoliwala, Saikat Ghosh, Late Ambikanandan Misra, Mrunali Patel, Hetal Thakkar

Publikováno v: International Journal of Pharmaceutics. 623:121863

Adagen, an enzyme replacement treatment for adenosine deaminase deficiency, was the first protein-polymer conjugate to be approved in early 1990 s. Post this regulatory approval, numerous polymeric drugs and polymeric nanoparticles have entered the m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f918dff75626a04e2aa399ddba931973
https://doi.org/10.1016/j.ijpharm.2022.121863

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Triple negative breast cancer and non-small cell lung cancer: Clinical challenges and nano-formulation approaches

Autor: Krutika K. Sawant, Subhas Balaram Bhowmick, Ankit Javia, A. J. Khopade, Shubhadeep Banerjee, Kuntal Maiti, Ambikanandan Misra, Saritha Shetty, Saikat Ghosh, Denish Bardoliwala

Publikováno v: Journal of controlled release : official journal of the Controlled Release Society. 337

Triple negative breast cancer (TNBC) and non-small cell lung cancer (NSCLC) are amongst the most aggressive forms of solid tumors. TNBC is highlighted by absence of genetic components of progesterone receptor, HER2/neu and estrogen receptor in breast

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::804af416674cb1ece149745f19faa6ee
https://pubmed.ncbi.nlm.nih.gov/34273417

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Applications of Polymers in Colon Drug Delivery

Autor: Dipesh Baradia, Ambikanandan Misra, Jitendra Amrutiya, Denish Bardoliwala

Publikováno v: Applications of Polymers in Drug Delivery ISBN: 9780128196595

Colon-targeted drug delivery possesses numerous advantages in pharmaceutical delivery systems. Both local and systemic deliveries of active ingredients are possible with help of polymers in colon-targeted delivery. Targeting colon can be helpful in p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6ef83bd4ab35159672bd1ef19d898686
https://doi.org/10.1016/b978-0-12-819659-5.00007-0

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