Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Denise Teotico Pohlhaus"'
Autor:
Emese Csoke, Sabine Landes, Matthew J. Francis, Larry Ma, Denise Teotico Pohlhaus, Christelle Anquez‐Traxler
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 1, Pp 43-54 (2022)
Abstract Real‐world evidence (RWE) is an emerging scientific discipline which is being increasingly utilized for decision making on prescription‐only medicines. However, there has been little focus to date on the application of RWE within the non
Externí odkaz:
https://doaj.org/article/1cc6a753d17a448a968524deecc7ca69
Autor:
Larry Ma, Denise Teotico Pohlhaus, Sabine Landes, Emese Csoke, Christelle Anquez-Traxler, Matthew J. Francis
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 1, Pp 43-54 (2022)
Clinical and Translational Science
Clinical and Translational Science
Real-world evidence (RWE) is an emerging scientific discipline which is being increasingly utilised for decision making on prescription only medicines. However, there has been little focus to date on the application of RWE within the non-prescription
Autor:
Corey Nislow, Ronald W. Davis, Peihua Yuan, Vytas A. Bankaitis, Iain M. Wallace, Sweety D. Shah, Aaron H. Nile, Carl J. Mousley, Brenda Temple, Guri Giaever, Robert P. St.Onge, Ashutosh Tripathi, Alexander Tropsha, Sundari Suresh, Denise Teotico Pohlhaus
Publikováno v:
Nature chemical biology
Sec14-like phosphatidylinositol transfer proteins (PITPs) integrate diverse territories of intracellular lipid metabolism with stimulated phosphatidylinositol-4-phosphate production and are discriminating portals for interrogating phosphoinositide si
Autor:
Oliv Eidam, Kerim Babaoglu, Richard Bonnet, Emilia Caselli, Brian K. Shoichet, Denise Teotico Pohlhaus, Fabio Prati, Joel Karpiak, Chiara Romagnoli
Publikováno v:
Journal of Medicinal Chemistry. 53:7852-7863
We investigated a series of sulfonamide boronic acids that resulted from the merging of two unrelated AmpC β-lactamase inhibitor series. The new boronic acids differed in the replacement of the canonical carboxamide, found in all penicillin and ceph
Autor:
Yu Chen, Denise Teotico Pohlhaus
Publikováno v:
Drug discovery today. Technologies. 7(3)
Molecular docking has become a valuable technique for structure-based drug discovery, including fragment-based approaches. This review summarizes the latest development in screening technologies using fragment docking and scoring, including probing b