Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Denise Spero"'
Autor:
Richard M. Nelson, Emeigh Jonathan Emilian, Terence A. Kelly, Gregory W. Peet, Eugene R. Hickey, Jiang-Ping Wu, Jun Li, Clare Zimmitti, Janice R. Brickwood, John D. Ginn, Charles L. Cywin, Melissa Foerst, David Stefany, Erika Scouten, Roman Wolfgang Fleck, Zhidong Chen, Mohammed A. Kashem, Daniel Richard Marshall, Steve M. Weldon, Ming-Hong Hao, Weimin Liu, Matt Hrapchak, Catron Katrina Mary, Ian Potocki, Tina Morwick, Peter Allen Nemoto, Michel Liuzzi, Leslie Martin, Denise Spero, Alison Capolino, Michael Robert Turner
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:5547-5551
An SAR study that identified a series of thienopyridine-based potent IkappaB Kinase beta (IKKbeta) inhibitors is described. With focuses on the structural optimization at C4 and C6 of structure 1 (Fig. 1), the study reveals that small alkyl and certa
Publikováno v:
The Journal of Immunology. 190:192.20-192.20
Emerging and re-emerging infectious diseases represent a significant challenge for next-generation vaccine design and bioterror preparedness. We have composed a suite of online immunoinformatics tools for accelerated design of genome-derived, epitope