Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Denise S. Malcolm"'
Autor:
Katarzyna Roguska, Rey A. Carabeo, Antonio T. Pedrosa, Richard D. Hayward, Sevanna Shahbazian, James E. Graham, Amanda J. Brinkworth, Denise S. Malcolm
Publikováno v:
Molecular Microbiology. 82:131-144
Bacterial type III secretion system (T3SS) chaperones pilot substrates to the export apparatus in a secretion-competent state, and are consequently central to the translocation of effectors into target cells. Chlamydia trachomatis is a genetically in
Autor:
Clare E. Futter, Caroline Powell, Marc Bruyland, John Collinge, Astrid Authier, Elizabeth M. C. Fisher, Adrian M. Isaacs, Hazel Urwin, Ida Elisabeth Holm, Jeremy P Brown, Peter Johannsen, Sebastian Brandner, Denise S. Malcolm, Daniel J. Metcalf, Julie van der Zee, Kristina E. Froud, Christine Van Broeckhoven, Jørgen E. Nielsen
Publikováno v:
Human molecular genetics
Human Molecular Genetics
Human Molecular Genetics
Mutations in CHMP2B cause frontotemporal dementia (FTD) in a large Danish pedigree, which is termed FTD linked to chromosome 3 (FTD-3), and also in an unrelated familial FTD patient. CHMP2B is a component of the ESCRT-III complex, which is required f
Publikováno v:
Science. 291:872-875
Replicative senescence is thought to be an intrinsic mechanism for limiting the proliferative life-span of normal somatic cells. We show here that rat Schwann cells can be expanded indefinitely in culture while maintaining checkpoints normally lost d
Autor:
Christopher C. Thompson, Rey A. Carabeo, Denise S. Malcolm, Scott S. Grieshaber, Sophie S. Nicod
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 109(26)
The regulation of iron homeostasis is essential for most organisms, because iron is required for a variety of conserved biochemical processes, yet can be toxic at high concentrations. Upon experiencing iron starvation in vitro, the obligate intracell
Autor:
Martha Kollb-Sielecka, David A. Goodwin, Chaminda Dooldeniya, Giti Garthwaite, Denise S. Malcolm, Katalin Bartus, John Garthwaite
Brain function is usually perceived as being performed by neurons with the support of glial cells, the network of blood vessels situated nearby serving simply to provide nutrient and to dispose of metabolic waste. Revising this view, we find from exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89697cfdf7ed85865f00f9b7cf4129eb
https://europepmc.org/articles/PMC6674268/
https://europepmc.org/articles/PMC6674268/
Publikováno v:
Molecular and cellular biology. 23(7)
Although oncogenic Ras commonly contributes to the development of cancer, in normal primary cells it induces cell cycle arrest rather than transformation. Here we analyze the additional genetic changes required for Ras to promote cell cycle progressi