Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Denise Mollica, Marotta"'
Autor:
Hugo A. M. Torres, Robson Costa, João Bosco Pesquero, Marianne N. Manjavachi, João B. Calixto, Luiz Juliano, Denise Mollica Marotta, Emerson Marcelo Motta
Publikováno v:
British Journal of Pharmacology. 159:888-897
Background and purpose: Activation of the proteinase-activated receptor-2 (PAR-2) induces scratching behaviour in mice. Here, we have investigated the role of kinin B1 and B2 receptors in the pruritogenic response elicited by activators of PAR-2. Exp
Autor:
Juliana F. Lima-Garcia, Ana Flavia Paszcuk, Susan D. Brain, Elizabeth S. Fernandes, Robson Costa, Luiz Juliano, João B. Calixto, Marianne N. Manjavachi, Denise Mollica Marotta, Nara Lins Meira Quintão
Publikováno v:
British Journal of Pharmacology. 154:1094-1103
Background and purpose: We investigated the mechanisms underlying the pruritogenic response induced by trypsin in mice, to assess the relevance of neurogenic inflammation components in this response. Experimental approach: Itching was induced by an i
Autor:
Denise Mollica Marotta, Cândida Aparecida Leite Kassuya, João B. Calixto, Vera Lúcia Garcia Rehder, Octavio Menezes-de-Lima, Aline Silvestre
Publikováno v:
European Journal of Pharmacology. 546:182-188
Previous studies have shown that the extracts obtained from Phyllanthus amarus, and some of the lignans isolated from it, exhibit pronounced antiinflammatory properties. In the present study, we have assessed whether the antiinflammatory actions of t
Autor:
Daniela F. P. Leite, João B. Calixto, Denise Mollica Marotta, Emerson Marcelo Motta, Marianne N. Manjavachi
Publikováno v:
PainReferences. 151(2)
Interleukin-6 (IL-6) is an inflammatory cytokine known to modulate muscle pain. However, the mechanisms underlying this effect still remain unclear. Here we show that the injection of IL-6 into mice gastrocnemius muscle evoked a time- and dose-depend
Autor:
João B. Calixto, Elizabeth S. Fernandes, Rodrigo Medeiros, Maria M. Campos, Denise Mollica Marotta, Emerson Marcelo Motta, Robson Costa, Nara Lins Meira Quintão
Publikováno v:
Biochemical pharmacology. 77(7)
Platelet-activating factor (PAF) is an inflammatory mediator widely known to exert relevant pathophysiological functions. However, the relevance of PAF in nociception has received much less attention. Herein, we have investigated the mechanisms under
Autor:
Cândida A L, Kassuya, Aline, Silvestre, Octávio, Menezes-de-Lima, Denise Mollica, Marotta, Vera Lúcia G, Rehder, João B, Calixto
Publikováno v:
European journal of pharmacology. 546(1-3)
Previous studies have shown that the extracts obtained from Phyllanthus amarus, and some of the lignans isolated from it, exhibit pronounced antiinflammatory properties. In the present study, we have assessed whether the antiinflammatory actions of t
Several Phyllanthus species are widely used in traditional medicine and herbal formulation for the treatment of a variety of ailments such as flu, dropsy, diabetes, jaundice and bladder calculus. The medicinal properties of these species are due to t