Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Denise Melvin"'
Autor:
Cecily Choy, Joseph Chen, Jiangyuan Li, D. Travis Gallagher, Jian Lu, Daichao Wu, Ainslee Zou, Humza Hemani, Beverly A. Baptiste, Emily Wichmann, Qian Yang, Jeffrey Ciffelo, Rui Yin, Julia McKelvy, Denise Melvin, Tonya Wallace, Christopher Dunn, Cuong Nguyen, Chee W. Chia, Jinshui Fan, Jeannie Ruffolo, Linda Zukley, Guixin Shi, Tomokazu Amano, Yang An, Osorio Meirelles, Wells W. Wu, Chao-Kai Chou, Rong-Fong Shen, Richard A. Willis, Minoru S. H. Ko, Yu-Tsueng Liu, Supriyo De, Brian G. Pierce, Luigi Ferrucci, Josephine Egan, Roy Mariuzza, Nan-Ping Weng
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract The resolution of SARS-CoV-2 replication hinges on cell-mediated immunity, wherein CD8+ T cells play a vital role. Nonetheless, the characterization of the specificity and TCR composition of CD8+ T cells targeting non-spike protein of SARS-C
Externí odkaz:
https://doaj.org/article/963224e732b44fa8b3d0805dabc27063
Autor:
Konstantinos I. Avgerinos, Roger J. Mullins, Michael Vreones, Maja Mustapic, Qinghua Chen, Denise Melvin, Dimitrios Kapogiannis, Josephine M. Egan
Publikováno v:
Cells, Vol 11, Iss 21, p 3372 (2022)
Sodium-glucose cotransporter-2 inhibitors (SGLT2is), such as empagliflozin, lower blood glucose in type 2 diabetes mellitus and improve cardiorenal outcomes regardless of diabetes presence. Whether SGLT2is exert any effects on the brain’s metabolis
Externí odkaz:
https://doaj.org/article/77f1e49489924160b2b7e44760783672
Autor:
Mustapha Bouhrara, Luis E. Cortina, Abinand C. Rejimon, Nikkita Khattar, Christopher Bergeron, Janet Bergeron, Denise Melvin, Linda Zukley, Richard G. Spencer
Publikováno v:
NeuroImage, Vol 206, Iss , Pp 116307- (2020)
Previous in-vivo magnetic resonance imaging (MRI)-based studies of age-related differences in the human brainstem have focused on volumetric morphometry. These investigations have provided pivotal insights into regional brainstem atrophy but have not
Externí odkaz:
https://doaj.org/article/a43e6da55dcc488f891affd8660adb97
Autor:
Luigi Ferrucci, Christopher M. Bergeron, Denise Melvin, Wenshu Qian, Richard W Kim, Linda Zukley, Mustapha Bouhrara, Nikkita Khattar, Richard G. Spencer, Susan M. Resnick
Publikováno v:
Human Brain Mapping
The g‐ratio, defined as the inner‐to‐outer diameter of a myelinated axon, is associated with the speed of nerve impulse conduction, and represents an index of axonal myelination and integrity. It has been shown to be a sensitive and specific bi
Autor:
Cecily Choy, Jian Lu, Jiangyuan Li, Humza Hemani, Joseph Chen, Ana Lustig, Julia McKelvey, Denise Melvin, Jeannie Ruffolo, Linda Zukley, Tonya Wallace, Christopher Dunn, Cuong Nguyen, Jinshui Fan, Supriyo De, Chee Chia, Luigi Ferrucci, Josephine Egan, Nan-ping Weng
Publikováno v:
The Journal of Immunology. 208:125.19-125.19
COVID-19, an infectious disease caused by SARS-CoV-2, has given rise to the current global pandemic. Despite the number of infections nearing 300 million people worldwide, CD8+ T cells against SARS-CoV-2 in COVID-19 convalescent, vaccinated, and heal
Autor:
Cecily Choy, Jian Lu, Jiangyuan Li, Christopher Dunn, Tonya Wallace, Cuong Nguyen, Julia McKelvey, Denise Melvin, Josephine Egan, Nan-Ping Weng
Publikováno v:
The Journal of Immunology. 206:103.16-103.16
COVID-19, an infectious disease caused by SARS-CoV-2, has caused the current global pandemic. Despite the number of infections nearing 100 million people worldwide, the CD8+ T cells against SARS-CoV-2 in healthy adults as well as in convalescent COVI
Autor:
Johannes D. Veldhuis, Shehzad Basaria, Michelle Shardell, Olga D. Carlson, Jenny Pena Dias, Chee Wei Chia, Denise Melvin, Josephine M. Egan
Publikováno v:
Metabolism. 69:143-147
Growth hormone is the major regulator of growth and body composition. Pulsatile GH secretion declines exponentially with age. Testosterone replacement is being increasingly offered to older men with age-related low testosterone. Testosterone administ
Autor:
Olga D. Carlson, Chee Wei Chia, Shehzad Basaria, Josephine M. Egan, Michelle Shardell, Jenny Pena Dias, Denise Melvin, Luigi Ferrucci, Giorgio Caturegli
Publikováno v:
Andrology. 5:31-40
Summary Testosterone (T) replacement is being increasingly offered to older men with age-related decline in testosterone levels. The effects of long-term testosterone replacement and aromatase inhibition (AI) on glucose homeostasis and cardiometaboli
Autor:
Denise Melvin, Michelle Shardell, Shehzad Basaria, Mohsen Gharib, Josephine M. Egan, Jenny Pena Dias, Chee Wei Chia, Luigi Ferrucci
Publikováno v:
The Journal of clinical endocrinology and metabolism. 101(4)
Context:T replacement is being increasingly offered to older men with age-related low T; hence, monitoring prostate health is important during T therapy. Data suggest that estrogens have an independent effect on the prostate and some effects of T on
Autor:
Jenny Pena Dias, Shehzad Basaria, Josephine M. Egan, Olga D. Carlson, Shardell, Luigi Ferrucci, Denise Melvin, Chee Wei Chia, Eleanor M. Simonsick
Aging in men is associated with loss of bone mass, impaired physical function and altered body composition. The objective of this proof-of-concept randomized, double-blind, placebo-controlled, parallel-group, single-center trial was to determine the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::679400ddc6cff10d7c5b5c04295955f5
https://europepmc.org/articles/PMC5836312/
https://europepmc.org/articles/PMC5836312/