Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Denise M. O'Sullivan"'
Autor:
Kathleen Gärtner, Sara Domínguez-Rodríguez, Judith Heaney, Triantafylia Gkouleli, Paul Grant, Karim Dorgham, Delphine Sauce, Cathia Soulie, Eloise J. Busby, Denise M. O’Sullivan, Moira Spyer, Johannes C. Botha, Maria Angeles Muñoz-Fernandez, Alfredo Tagarro, Nicola Cotugno, Jim F. Huggett, Nigel Klein, Paolo Palma, Pablo Rojo Conejo, Caroline Foster, Carlo Giaquinto, Paolo Rossi, Deborah Persaud, Anita De Rossi, Anne-Geneviève Marcelin, Eleni Nastouli
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionInitiation of antiretroviral treatment (ART) in patients early after HIV-infection and long-term suppression leads to low or undetectable levels of HIV RNA and cell-associated (CA) HIV DNA and RNA. Both CA-DNA and CA-RNA, overestimate the
Externí odkaz:
https://doaj.org/article/4ff5de9e0e7d46feaef69aac5332bac4
Autor:
Laura Vierbaum, Nathalie Wojtalewicz, Hans-Peter Grunert, Anika Zimmermann, Annemarie Scholz, Sabine Goseberg, Patricia Kaiser, Ulf Duehring, Christian Drosten, Victor Corman, Daniela Niemeyer, Holger F. Rabenau, Martin Obermeier, Andreas Nitsche, Janine Michel, Andreas Puyskens, Jim F. Huggett, Denise M. O’Sullivan, Eloise Busby, Simon Cowen, Peter M. Vallone, Megan H. Cleveland, Samreen Falak, Andreas Kummrow, Ingo Schellenberg, Heinz Zeichhardt, Martin Kammel
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract The COVID-19 pandemic illustrated the important role of diagnostic tests, including lateral flow tests (LFTs), in identifying patients and their contacts to slow the spread of infections. INSTAND performed external quality assessments (EQA)
Externí odkaz:
https://doaj.org/article/382f64418a09458f986183c39daac0a4
Autor:
Eloise J. Busby, Ronan M. Doyle, Clara Leboreiro Babe, Kathryn A. Harris, Damien Mack, Gema Méndez-Cervantes, Denise M. O’Sullivan, Vicky Pang, Zahra Sadouki, Priya Solanki, Jim F. Huggett, Timothy D. McHugh, Emmanuel Q. Wey
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT Colonization and subsequent health care-associated infection (HCAI) with Acinetobacter baumannii are a concern for vulnerable patient groups within the hospital setting. Outbreaks involving multidrug-resistant strains are associated with inc
Externí odkaz:
https://doaj.org/article/91c090f3182c483d810e3595b6b29a35
Autor:
Denise M. O’Sullivan, Ronan M. Doyle, Sasithon Temisak, Nicholas Redshaw, Alexandra S. Whale, Grace Logan, Jiabin Huang, Nicole Fischer, Gregory C. A. Amos, Mark D. Preston, Julian R. Marchesi, Josef Wagner, Julian Parkhill, Yair Motro, Hubert Denise, Robert D. Finn, Kathryn A. Harris, Gemma L. Kay, Justin O’Grady, Emma Ransom-Jones, Huihai Wu, Emma Laing, David J. Studholme, Ernest Diez Benavente, Jody Phelan, Taane G. Clark, Jacob Moran-Gilad, Jim F. Huggett
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Despite the advent of whole genome metagenomics, targeted approaches (such as 16S rRNA gene amplicon sequencing) continue to be valuable for determining the microbial composition of samples. Amplicon microbiome sequencing can be performed on
Externí odkaz:
https://doaj.org/article/8468c62cda324455a0cd7a1fb1c847ee
Autor:
Yann Le Duff, Kathleen Gärtner, Eloise J. Busby, Annalisa Dalzini, Sivapragashini Danaviah, José Luis Jiménez Fuentes, Carlo Giaquinto, Jim F. Huggett, Matthew Hurley, Anne-Geneviève Marcellin, María Ángeles Muñoz-Fernández, Denise M. O’Sullivan, Deborah Persaud, Laura Powell, Peter Rigsby, Paolo Rossi, Anita de Rossi, Lilly Siems, Theresa Smit, Sarah A. Watters, Neil Almond, Eleni Nastouli
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 3 (2022)
ABSTRACT Reliable and accurate quantification of cell-associated HIV DNA (CA HIV DNA) is critical for early infant diagnosis, clinical management of patients under therapy, and to inform new therapeutics efficacy. The present study assessed the varia
Externí odkaz:
https://doaj.org/article/94c480c573cc4c8dacfb127ce8fbdce8
Autor:
Jody E. Phelan, Denise M. O’Sullivan, Diana Machado, Jorge Ramos, Yaa E. A. Oppong, Susana Campino, Justin O’Grady, Ruth McNerney, Martin L. Hibberd, Miguel Viveiros, Jim F. Huggett, Taane G. Clark
Publikováno v:
Genome Medicine, Vol 11, Iss 1, Pp 1-7 (2019)
Abstract Background Mycobacterium tuberculosis resistance to anti-tuberculosis drugs is a major threat to global public health. Whole genome sequencing (WGS) is rapidly gaining traction as a diagnostic tool for clinical tuberculosis settings. To supp
Externí odkaz:
https://doaj.org/article/9f8688694fb84bd68eaa395843a4a02b
Autor:
Denise M. O'Sullivan, Thomas Laver, Sasithon Temisak, Nicholas Redshaw, Kathryn A. Harris, Carole A. Foy, David J. Studholme, Jim F. Huggett
Publikováno v:
International Journal of Molecular Sciences, Vol 15, Iss 11, Pp 21476-21491 (2014)
The application of high-throughput sequencing in profiling microbial communities is providing an unprecedented ability to investigate microbiomes. Such studies typically apply one of two methods: amplicon sequencing using PCR to target a conserved or
Externí odkaz:
https://doaj.org/article/2500e7503ca74c8a9b989d4f405c41cd
Autor:
Tim Mercer, Neil Almond, Michael A. Crone, Patrick S. G. Chain, Alina Deshpande, Deepa Eveleigh, Paul Freemont, Sebastien Fuchs, Russell Garlick, Jim Huggett, Martin Kammel, Po-E Li, Mojca Milavec, Elizabeth M. Marlowe, Denise M. O’Sullivan, Mark Page, Gary A. Pestano, Sara Suliman, Birgitte Simen, John J. Sninsky, Lynne Sopchak, Cristina M. Tato, Peter M. Vallone, Jo Vandesompele, Thomas J. White, Heinz Zeichhardt, Marc Salit
Publikováno v:
Nature Biotechnology. 40:1563-1568
Autor:
Martin Kammel, Samreen Falak, Jim F. Huggett, Annabell Plauth, Denise M. O'Sullivan, Rainer Macdonald, Mojca Milavec, Heinz Zeichhardt, Andreas Kummrow, Eloise J. Busby, Hans-Peter Grunert
Publikováno v:
Methods. 201:34-40
Viral load monitoring in human immunodeficiency virus type 1 (HIV-1) infection is often performed using reverse transcription quantitative PCR (RT-qPCR) to observe response to treatment and identify the development of resistance. Traceability is achi
Autor:
Denise M. O'Sullivan, Ki Ho Hong, Kathryn A. Harris, Jacob Moran-Gilad, Daniel Evans, Jiwon In, Heinz Zeichhardt, Martin Kammel, Julian Braybrook, Suzie Hingley-Wilson, Ulf Dühring, Jo Vandesompele, Nathaniel Storey, Jim F. Huggett, Carole A. Foy, Simon Cowen, Graham R. Stewart, Young-Kyung Bae, Jasper Verwilt, Hans-Peter Grunert
Publikováno v:
CLINICAL CHEMISTRY
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA quantities, measured by reverse transcription quantitative PCR (RT-qPCR), have been proposed to stratify clinical risk or determine analytical performance targets. We investi