Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Denise M. Gibo"'
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 4, Iss 5, Pp 388-399 (2002)
We have found that binding sites for interleukin-13. ( IL13) are overexpressed in a vast majority of high-grade astrocytomas. (HGAs). These binding sites for IL-13 are distinct from the physiological receptor in that it does not bind IL-4. We also de
Externí odkaz:
https://doaj.org/article/94a443570ceb4fc78c8a059b46df8a2d
Publikováno v:
Neuro-Oncology. 14:6-18
Interleukin 13 receptor α 2 (IL-13Rα2) is a glioblastoma multiforme (GBM)-associated plasma membrane receptor, a brain tumor of dismal prognosis. Here, we isolated peptide ligands for IL-13Rα2 with use of a cyclic disulphide-constrained heptapepti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0adcf4e9b77fb8f4d3938a78f7c9f36c
https://doi.org/10.1093/neuonc/nor141
https://doi.org/10.1093/neuonc/nor141
Autor:
Denise M. Gibo, Waldemar Debinski
Publikováno v:
Cancer Biology & Therapy. 11:254-262
Fos-related antigen 1 (Fra-1) plays an important role in maintenance/progression of various cancers, including glioblastoma multiforme (GBM). In this study, we used both shRNA and siRNA to examine the effect of fra-1 knockdown in GBM cells over-expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1542038f8ba7fa2219c1e993cae53be8
https://doi.org/10.4161/cbt.11.2.13953
https://doi.org/10.4161/cbt.11.2.13953
Publikováno v:
Clinical Cancer Research. 15:160-168
Purpose: Hypoxia is a cause for resistance to cancer therapies. Molecularly targeted recombinant cytotoxins have shown clinical efficacy in the treatment of patients with primary brain tumors, glioblastoma multiforme, but it is not known whether hypo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c2f443d573ba40c00174eec89f5b2cd
https://doi.org/10.1158/1078-0432.ccr-08-2151
https://doi.org/10.1158/1078-0432.ccr-08-2151
Autor:
Kevin K. Lahmers, Waldemar Debinski, Kurt L. Zimmerman, John H. Rossmeisl, Thomas E. Cecere, Denise M. Gibo, Tanya LeRoith, Rudy T. Andriani
Publikováno v:
Frontiers in Veterinary Science
Frontiers in Veterinary Science, Vol 2 (2015)
Frontiers in Veterinary Science, Vol 2 (2015)
This report describes the methodology, diagnostic yield, and adverse events (AE) associated with frame-based stereotactic brain biopsies (FBSB) obtained from 26 dogs with solitary forebrain lesions. Medical records were reviewed from dogs that underw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e29121b94599497cdfe3ca45f3834246
http://europepmc.org/articles/PMC4672202
http://europepmc.org/articles/PMC4672202
Publikováno v:
Molecular Cancer Research. 3:541-551
We investigated the presence of EphA2, and its ligand, ephrinA1, in glioblastoma multiforme (GBM), a malignant neoplasm of glial cells, and normal brain. We also initially examined the functional importance of the interaction between EphA2 and ephrin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f24c4ddc5e7c786c003b836ec4cf8d98
https://doi.org/10.1158/1541-7786.mcr-05-0056
https://doi.org/10.1158/1541-7786.mcr-05-0056
Publikováno v:
Annals of the New York Academy of Sciences. 983:232-242
Human high-grade astrocytomas (HGA) are the most prevalent incurable brain tumors. We found that the vast majority of HGA patients overexpress a restricted receptor for an immune regulatory cytokine, interleukin 13 (IL-13). Interestingly, the HGA-ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09f03595e390fe8cb5281d7937773e16
https://doi.org/10.1111/j.1749-6632.2003.tb05978.x
https://doi.org/10.1111/j.1749-6632.2003.tb05978.x
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 4, Iss 5, Pp 388-399 (2002)
We have found that binding sites for interleukin-13 (IL-13) are overexpressed in a vast majority of high-grade astrocytomas (HGAs). These binding sites for IL-13 are distinct from the physiological receptor in that it does not bind IL-4. We also demo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9226855b5b32602f0b7bc6f4e683d2c
Autor:
Stephen B. Tatter, Mark O. Lively, Lance D. Miller, Darren F. Seals, Analiz Rodriguez, Waldemar Debinski, Ryan T. Mott, Denise M. Gibo
BACKGROUND: Tumor associated macrophages (TAMS) have been suggested to be key players in the tumor microenvironment. The M2 activation phenotype is believed to be the predominant TAM phenotype in solid tumors. To further define the role of M2 TAMs an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5e35e6e004960ac5101246347c0c5b9
https://europepmc.org/articles/PMC4144615/
https://europepmc.org/articles/PMC4144615/
Autor:
Becky Slagle-Webb, Marc G. Achen, Eugene Tulchinsky, Steven A. Stacker, Denise M. Gibo, Waldemar Debinski, G. Yancey Gillespie
Publikováno v:
Molecular Medicine. 7:598-608
Glioblastoma multiforme (GBM) is a hypervascularized and locally infiltrating brain tumor of astroglial origin with a very poor prognosis. An X-linked c-fos oncogene-inducible mitogenic, morphogenic, and angiogenic factor, endothelial growth factor-D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::927abb051cc8adc1160d12f49cf52d7c
https://doi.org/10.1007/bf03401866
https://doi.org/10.1007/bf03401866