Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Denise Levitan"'
Autor:
Bayard L. Powell, Susan Lyerly, Sarah Dralle, Megan Manuel, Robin Harrelson, Leslie R. Ellis, David Hurd, Denise Levitan, Kristin M. Stadelman, Lance D. Miller, Scott Isom, Robert Rodriguez, Claudia Maturo, John Luddy, King Lee, Timothy S. Pardee
Purpose: The lipoate derivative CPI-613 is a first-in-class agent that targets mitochondrial metabolism. This study determined the effects of CPI-613 on mitochondrial function and defined the MTD, pharmacokinetics, and safety in patients with relapse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a94274ada13dbd409c8c48fe4c2e450f
https://doi.org/10.1158/1078-0432.c.6523629
https://doi.org/10.1158/1078-0432.c.6523629
Autor:
Bayard L. Powell, Susan Lyerly, Sarah Dralle, Megan Manuel, Robin Harrelson, Leslie R. Ellis, David Hurd, Denise Levitan, Kristin M. Stadelman, Lance D. Miller, Scott Isom, Robert Rodriguez, Claudia Maturo, John Luddy, King Lee, Timothy S. Pardee
Supplementary Figure 1. Pharmacokinetics of CPI-613 infused over 1 hour. Plasma CPI-613 levels following a 1 or 2 hour infusion shown on day 1 and day 6 on a linear scale. The number of patients in each analysis is indicated by n. **=p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e3fb3529a0980ffa12d525b98fdf809
https://doi.org/10.1158/1078-0432.22457619
https://doi.org/10.1158/1078-0432.22457619
Autor:
Bayard L. Powell, Susan Lyerly, Sarah Dralle, Megan Manuel, Robin Harrelson, Leslie R. Ellis, David Hurd, Denise Levitan, Kristin M. Stadelman, Lance D. Miller, Scott Isom, Robert Rodriguez, Claudia Maturo, John Luddy, King Lee, Timothy S. Pardee
Supplementary Figure 2. Differential gene expression between responders and non-responders. The top 50 genes up regulated in responders (left side) or non-responders (right side) in PBMCs from 4 responders compared to 4 non-responders taken on day 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09f2ff7c7bc3ec05fd622c1bd00e4f3a
https://doi.org/10.1158/1078-0432.22457616
https://doi.org/10.1158/1078-0432.22457616
Autor:
Scott Isom, Stephen B. Kritchevsky, Bayard L. Powell, Heidi D. Klepin, Janet A. Tooze, Ann M. Geiger, Timothy S. Pardee, Jeff D. Williamson, Denise Levitan, Leslie R. Ellis
Publikováno v:
Journal of the American Geriatrics Society. 59:1837-1846
Acute myelogenous leukemia (AML) is largely a disease of older adults and has disproportionately worse survival with older age; optimal therapy for older adults is unclear.1–4 The disease presents acutely and aggressively, requiring intense chemoth
Autor:
King Chung Lee, Timothy S. Pardee, John Luddy, Sarah Dralle, Robin Harrelson, David D. Hurd, Leslie R. Ellis, Bayard L. Powell, Robert J. Rodriguez, Kristin Stadelman, Claudia Maturo, Megan Manuel, Denise Levitan, Scott Isom, Susan Lyerly, Lance D. Miller
Purpose: The lipoate derivative CPI-613 is a first-in-class agent that targets mitochondrial metabolism. This study determined the effects of CPI-613 on mitochondrial function and defined the MTD, pharmacokinetics, and safety in patients with relapse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4edebe2b2d0164b35200c499fddb33f
https://europepmc.org/articles/PMC4199870/
https://europepmc.org/articles/PMC4199870/
Autor:
Jessica K. Altman, Meir Wetzler, Wendy Stock, Denise Levitan, Martin S. Tallman, Tracy Maher, Elisabeth Paietta, Steven Coutre, Steven D. Gore, Cheryl L. Willman, Richard A. Larson, Megan Othus, Kenneth J. Kopecky, Eyal C. Attar, Bayard L. Powell, Frederick R. Appelbaum
Publikováno v:
British journal of haematology. 165(4)
A total of 105 patients (age ≥ 18 years) with newly diagnosed low or intermediate risk acute promyelocytic leukaemia (APL) were treated with a standard induction and consolidation regimen including arsenic trioxide (ATO). Sixty-eight patients who w
Autor:
Gregory B. Russell, Kara Loth, Kenneth Zamkoff, David D. Hurd, Seema Naik, Denise Levitan, LeAnne Kennedy
Publikováno v:
Chemotherapy: Open Access.
Purpose/Background: Due to its mechanism, the use of antithymocyte globulin (ATG) in reduced intensity conditioning allogeneic stem cell transplant (RIC allo-SCT) therapy may increase the incidence of infection. This study analyzes the type and incid
Publikováno v:
Journal of drugs in dermatology : JDD. 9(8)
Topical 5-fluorouracil (5-FU) has been used in the treatment of various benign and malignant tumors of the skin, but only few address its therapeutic value on cutaneoues T-cell lymphoma. (CTCL). The authors report six cases of early stage CTCL respon
Publikováno v:
Clinical lymphoma, myelomaleukemia. 10(2)
Background: We report a retrospective study of 452 patients with lymphoma from 1991 to 2006, with 274 men and 178 women, median age of 50 years (range, 16-76 years). Patients and Methods: There were 85 patients with Hodgkin lymphoma (HL) and 367 with
Publikováno v:
Biology of Blood and Marrow Transplantation. 16(2)