Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Denise Lafreniere"'
Autor:
Dwaine F. Emerich, Karen Fu, Anthony S. Basile, Thomas W. Cooper, Leah Novak, Raymond T. Bartus, Heather C. Salzberg-Brenhouse, Ee-Sing Lo, Pam Snodgrass-Belt, Denise Lafreniere
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 310:828-835
The efficacy of oral L-dopa becomes problematic with the progression of Parkinson's disease, due in large part to a lost ability to accommodate L-dopa's inherently poor pharmacokinetics. Pulmonary delivery represents a novel approach to reducing this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a483d65e9867fc2d32e87d0701aa77c1
https://doi.org/10.1124/jpet.103.064121
https://doi.org/10.1124/jpet.103.064121
Autor:
Leah Novak, Heather C. Salzberg-Brenhouse, Anthony S. Basile, Brigido Perdomo, Raymond T. Bartus, Jeffrey H. Kordower, Sam Baldwin, Theodora Kladis, Karen Fu, Sharon Ranelli, Er-Yun Chen, Denise Lafreniere, Ken Hogeland, Dwaine F. Emerich
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 306:218-228
Cyclooxygenases (COXs) are implicated in neurodegenerative processes associated with acute and chronic neurological diseases. Given the potential utility of COX inhibitors in treating these disorders, we examined the nonselective COX inhibitor flurbi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c27b638d669ab8d88a150b334c2d7df
https://doi.org/10.1124/jpet.103.049700
https://doi.org/10.1124/jpet.103.049700
Autor:
Raymond T. Bartus, Denise Lafreniere, Reginald L. Dean, Shelley R. Winn, Mahin F. Arastu, Heather C. Salzberg, Pamela Snodgrass, Joanne Marsh, Brigido Perdomo, Dwaine F. Emerich
Publikováno v:
Pharmaceutical Research. 19:1052-1060
Purpose. The present studies evaluated the ability of injectable, biodegradable microspheres releasing carboplatin, doxorubicin, or 5-fluorouracil to suppress the growth of solid tumors implanted subcutaneously or intramuscularly.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fce8b66f4ff81cb5095c3c395de7b2d6
https://doi.org/10.1023/a:1016434926649
https://doi.org/10.1023/a:1016434926649
Autor:
Reginald L. Dean, Joanne Marsh, Melissa Pink, Raymond T. Bartus, Denise Lafreniere, Dwaine F. Emerich, Pamela Snodgrass
Publikováno v:
Pharmaceutical Research. 17:1212-1219
Purpose. The following experiments determined whether intravenous infusions of Cereport enhance delivery of chemotherapeutics and prolong survival in rats with metastatic tumors in the brain.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c1b406bedbc3dd3ee1c8ce3a1cad1d6
https://doi.org/10.1023/a:1026462629438
https://doi.org/10.1023/a:1026462629438
Autor:
Denise Lafreniere, Dwaine F. Emerich, S. R. Winn, Tania Wiens, Mary Agostino, Raymond T. Bartus, Hua Xiong, Pamela Snodgrass
Publikováno v:
Pharmaceutical Research. 17:776-781
Purpose. Delivery of chemotherapeutics using implantable,biodegradable polymers provides a potentially powerful method of treating braintumors. The present studies examined the ability of injectablemicrospheres, formulated to release carboplatin or B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5647b75b069ce7d408230d87e419e4f
https://doi.org/10.1023/a:1007591721877
https://doi.org/10.1023/a:1007591721877
Autor:
Tania Wiens, Denise Lafreniere, Raymond T. Bartus, S. R. Winn, Yunhua Hu, Brant P. Hasler, Pamela Snodgrass, Joanne Marsh, Dwaine F. Emerich
Publikováno v:
Pharmaceutical Research. 17:767-775
Purpose. Implantation of biodegradable polymers provides a powerfulmethod to deliver high, sustained concentrations of chemotherapeuticsto brain tumors. The present studies examined the ability of injectablepolymeric microspheres, formulated to relea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::558af5858ea38aedc9d1bda894818761
https://doi.org/10.1023/a:1007576405039
https://doi.org/10.1023/a:1007576405039
Autor:
Dwaine F, Emerich, Pamela, Snodgrass, Denise, Lafreniere, Reginald L, Dean, Heather, Salzberg, Joanne, Marsh, Brigido, Perdomo, Mahin, Arastu, Shelley R, Winn, Raymond T, Bartus
Publikováno v:
Pharmaceutical research. 19(7)
The present studies evaluated the ability of injectable, biodegradable microspheres releasing carboplatin, doxorubicin, or 5-fluorouracil to suppress the growth of solid tumors implanted subcutaneously or intramuscularly.Seven to 10 days after implan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7d8fa81aec9f3efeb440a8e7e4d3f331
https://pubmed.ncbi.nlm.nih.gov/12180539
https://pubmed.ncbi.nlm.nih.gov/12180539
Autor:
T, Bartus Raymond, Dwaine, Emerich, Pam, Snodgrass-Belt, Karen, Fu, Heather, Salzberg-Brenhouse, Denise, Lafreniere, Leah, Novak, Ee-Sing, Lo, Thomas, Cooper, S, Basile Anthony
Publikováno v:
The Journal of Pharmacology and Experimental Therapeutics; August 2004, Vol. 310 Issue: 2 p828-35, 8p