Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Denise L. Walker"'
Autor:
W. Michael Hooten, Victor M. Karpyak, Magdalena Romanowicz, Gen Shinozaki, Rajeswari Avula, Simon Kung, Ann M. Moyer, Sandra C. Bryant, William J. Hogan, Kelly K. Edwards, James R. Rundell, Denise L. Walker, Mark R. Litzow, John L. Black, Sheila G. Jowsey-Gregoire, Maria I. Lapid, Linnea M. Baudhuin, Shawna L. Ehlers
Publikováno v:
Genetic Testing and Molecular Biomarkers. 19:115-123
Recent reports have suggested an association between variation in the serotonin transporter and primary pulmonary hypertension and myocardial infarction. We set out to determine whether these associations were present in a population of patients who
Autor:
Doo Sup Choi, David J. Hinton, Osama A. Abulseoud, Katheryn M. O’Connor, Christina L. Ruby, Denise L. Walker, Chelsea A. Vadnie, Maria F. Noterman
Publikováno v:
Neuropsychopharmacology. 39:2432-2440
Circadian rhythm and sleep disruptions occur frequently in individuals with alcohol use disorders (AUD) and present significant barriers to treatment. Recently, a variant of adenosine transporter, equilibrative nucleoside transporter 1 (ENT1), was as
Autor:
Jennifer R. Geske, Stacey J. Winham, Terry D. Schneekloth, Julie M. Cunningham, Mark A. Frye, Larissa L. Loukianova, Joanna M. Biernacka, Victor M. Karpyak, Igor Bazov, John A. Heit, David A. Mrazek, Daniel K. Hall-Flavin, Kriste A. Lewis, Georgy Bakalkin, Colin L. Colby, Denise L. Walker, Ulrich W. Preuss, Osama A. Abulseoud, Peter Zill
Publikováno v:
International Journal of Neuropsychopharmacology. 16:975-985
Synthetic κ-opioid receptor (KOR) agonists induce dysphoric and pro-depressive effects and variations in the KOR (OPRK1) and prodynorphin (PDYN) genes have been shown to be associated with alcohol dependence. We genotyped 23 single nucleotide polymo
Autor:
Gen Shinozaki, Joanna M. Biernacka, James Rundell, Colin L. Colby, Denise L. Walker, David A. Mrazek, Hatem Amer, Mark D. Stegall, John Black, Sheila Jowsey
Publikováno v:
Depression and Anxiety. 28:1111-1118
Background: Several polymorphisms in FK506 Binding Protein gene (FKBP5) and a history of child abuse have been shown to be associated with an increased risk for posttraumatic stress disorder (PTSD). It has also been demonstrated that the same polymor
Autor:
Whitney Erin Kramer, J. L. Black, David A. Mrazek, Brian A. Dukek, Dennis J. O'Kane, Jamie K. Bruflat, Pamela K. Fisher, Denise L. Walker
Publikováno v:
Pharmacogenetics and Genomics. 19:813-822
CYP2D6 is a polymorphic gene. It has been observed to be deleted, to be duplicated and to undergo recombination events involving the CYP2D7 pseudogene and surrounding sequences. The objective of this study was to discover the genomic structure of CYP
Autor:
Denise L. Walker, Paul M. Thompson, Peter C. Harris, Lisa M. Guay-Woodford, J. Philip Miller, Sandro Rossetti, Kyongtae T. Bae, Mark B. Consugar, William M. Bennett, Arlene B. Chapman, Catherine M. Meyers, Qin Zhang, Jared J. Grantham, Vicente E. Torres
Publikováno v:
Journal of the American Society of Nephrology. 18:2143-2160
Mutation-based molecular diagnostics of autosomal dominant polycystic kidney disease (ADPKD) is complicated by genetic and allelic heterogeneity, large multi-exon genes, duplication of PKD1, and a high level of unclassified variants (UCV). Present mu
Autor:
Christopher A. Hilker, Julie M. Cunningham, Denise L. Walker, Saurabh Baheti, Zhifu Sun, Regenia L. Smalley, Aditya Bhagwate
Publikováno v:
Epigenomics. 7(8)
Aims: To compare the performance of four sequence-based and one microarray methods for DNA methylation profiling. Methods: DNA from two cell lines were profiled by reduced representation bisulfite sequencing, methyl capture sequencing (SS-Meth Seq),
Autor:
Paul A. Fredrickson, Nancy L. Slocumb, Denise L. Walker, John L. Black, V. Shane Pankratz, Rajeswari Avula, Michael H. Silber, Lois E. Krahn
Publikováno v:
Biological Psychiatry. 58:504-509
Background Canine models for narcolepsy have mutations of the hypocretin receptor 2 gene, and preprohypocretin knockout murine lines exhibit narcoleptic-like behaviors. Human narcolepsy with cataplexy is associated with human leukocyte antigen DQB1*0
Autor:
Patricia LoRusso, Andrew J. Tomlinson, Matthew M. Ames, Jennifer K. Miller, Denise L. Walker, Stephen Naylor, April L. Blajeski, Linda M. Benson, Joel M. Reid
Publikováno v:
Clinical Cancer Research. 10:1471-1480
Pyrazoloacridine (PZA) is an experimental antitumor agent presently under investigation for treatment of solid tumors on the basis of its unique mechanism of action and selectivity for human solid tumor xenograft in mice. Using capillary electrophore
Autor:
Marin Veldic, Simon Kung, Bruce Sutor, Lisa R. Seymour, Brian A. Palmer, Joanna M. Biernacka, Mohit Chauhan, Jennifer R. Geske, Miguel L. Prieto, Mark A. Frye, Kelly L. Harper, Christine W. Galardy, Alfredo B. Cuellar-Barboza, Denise L. Walker, Nicole Mori, Manuel Fuentes, Susan L. McElroy, Scott J. Crow
Publikováno v:
The Journal of clinical psychiatry. 76(2)
Introduction Identifying clinical and genetic risk factors associated with antidepressant-induced mania (AIM) may improve individualized treatment strategies for bipolar depression. Method From 2009 to 2012, bipolar depressed patients, confirmed by D