Zobrazeno 1 - 10
of 275
pro vyhledávání: '"Denise L. Doolan"'
Autor:
Daniel J. Browne, Catherine M. Miller, Emily P. O'Hara, Robert Courtney, Jamie Seymour, Denise L. Doolan, Ryan Orr
Publikováno v:
Environmental DNA, Vol 6, Iss 4, Pp n/a-n/a (2024)
Abstract Molecular detection of environmental DNA (eDNA) and RNA (eRNA) allows highly sensitive qualitative (i.e., presence or absence) and quantitative (i.e., abundance) monitoring of aquatic bacteria. However, bacterial molecular diagnostics are li
Externí odkaz:
https://doaj.org/article/60632d80ba25408096718b319a6460c3
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The collection, cryopreservation, thawing, and culture of peripheral blood mononuclear cells (PBMCs) can profoundly influence T cell viability and immunogenicity. Gold-standard PBMC processing protocols have been developed by the Office of HIV/AIDS N
Externí odkaz:
https://doaj.org/article/9dcc9cff28c14c7f9b16dd945e28ed56
Autor:
Daniel J. Browne, Ashton M. Kelly, Jamie Brady, Carla Proietti, Yomani D. Sarathkumara, David J. Pattinson, Denise L. Doolan
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract The efficacy of pre-erythrocytic stage malaria antigens or vaccine platforms is routinely assessed in murine models challenged with Plasmodium sporozoites. Relative liver-stage parasite burden is quantified using reverse transcription quanti
Externí odkaz:
https://doaj.org/article/33385b24b435431abfbe173b985c6da5
Autor:
Amali Karunathilaka, Samuel Halstrom, Patricia Price, Michael Holt, Viviana P. Lutzky, Denise L. Doolan, Andreas Kupz, Scott C. Bell, Rachel M. Thomson, John J. Miles, Champa N. Ratnatunga
Publikováno v:
Immunity & Ageing, Vol 19, Iss 1, Pp 1-8 (2022)
Abstract γδ T cells are a highly versatile immune lineage involved in host defense and homeostasis, but questions remain around their heterogeneity, precise function and role during health and disease. We used multi−parametric flow cytometry, dim
Externí odkaz:
https://doaj.org/article/fb172ebadebe414fa4a5dedc70fc85ea
Autor:
Anna E. Coghill, Jianwen Fang, Zhiwei Liu, Chien-Jen Chen, Ruth F. Jarrett, Henrik Hjalgrim, Carla Proietti, Kelly J. Yu, Wan-Lun Hsu, Pei-Jen Lou, Chen-Ping Wang, Yingdong Zhao, Denise L. Doolan, Allan Hildesheim
Publikováno v:
International Journal of Infectious Diseases, Vol 114, Iss , Pp 65-71 (2022)
ABSTRACT: Background: Epstein–Barr virus (EBV) infection contributes to cancers in a fraction of seropositive individuals, but much remains to be learned about variation in EBV-directed humoral immunity in cancer-free adults. Methods: A protein mic
Externí odkaz:
https://doaj.org/article/bb033c0992f74958a4dbcc75d7993452
Characterization of the humoral immune response to the EBV proteome in extranodal NK/T-cell lymphoma
Autor:
Zhiwei Liu, Yomani D. Sarathkumara, John K. C. Chan, Yok-Lam Kwong, Tai Hing Lam, Dennis Kai Ming Ip, Brian C.-H. Chiu, Jun Xu, Yu-Chieh Su, Carla Proietti, Martha M. Cooper, Kelly J. Yu, Bryan Bassig, Raymond Liang, Wei Hu, Bu-Tian Ji, Anna E. Coghill, Ruth M. Pfeiffer, Allan Hildesheim, Nathaniel Rothman, Denise L. Doolan, Qing Lan
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Extranodal natural killer/T-cell lymphoma (NKTCL) is an aggressive malignancy that has been etiologically linked to Epstein-Barr virus (EBV) infection, with EBV gene transcripts identified in almost all cases. However, the humoral immune res
Externí odkaz:
https://doaj.org/article/96c0c569af1e43a0b758847bbd7d9102
Autor:
Champa N. Ratnatunga, Katie Tungatt, Carla Proietti, Sam Halstrom, Michael R. Holt, Viviana P. Lutzky, Patricia Price, Denise L. Doolan, Scott C. Bell, Matt A. Field, Andreas Kupz, Rachel M. Thomson, John J. Miles
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Non-tuberculous mycobacterial pulmonary disease (NTM-PD) is a chronic, progressive, and growing worldwide health burden associated with mounting morbidity, mortality, and economic costs. Improvements in NTM-PD management are urgently needed, which re
Externí odkaz:
https://doaj.org/article/fba668e651114e49b81917d41e8bd331
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Immunoassays that quantitate cytokines and other surrogate markers of immunity from peripheral blood mononuclear cells (PBMCs), such as flow cytometry or Enzyme-Linked Immunosorbent Spot (ELIspot), allow highly sensitive measurements of immune effect
Externí odkaz:
https://doaj.org/article/09c97a78b98d4975ad7bc8257ae73d8a
Systems serology detects functionally distinct coronavirus antibody features in children and elderly
Autor:
Kevin J. Selva, Carolien E. van de Sandt, Melissa M. Lemke, Christina Y. Lee, Suzanne K. Shoffner, Brendon Y. Chua, Samantha K. Davis, Thi H. O. Nguyen, Louise C. Rowntree, Luca Hensen, Marios Koutsakos, Chinn Yi Wong, Francesca Mordant, David C. Jackson, Katie L. Flanagan, Jane Crowe, Shidan Tosif, Melanie R. Neeland, Philip Sutton, Paul V. Licciardi, Nigel W. Crawford, Allen C. Cheng, Denise L. Doolan, Fatima Amanat, Florian Krammer, Keith Chappell, Naphak Modhiran, Daniel Watterson, Paul Young, Wen Shi Lee, Bruce D. Wines, P. Mark Hogarth, Robyn Esterbauer, Hannah G. Kelly, Hyon-Xhi Tan, Jennifer A. Juno, Adam K. Wheatley, Stephen J. Kent, Kelly B. Arnold, Katherine Kedzierska, Amy W. Chung
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Antibody responses to SARS-CoV-2 are critical in the immune response to infection, but the potential cross-reactivity to other human corona viruses is poorly appreciated. Here the authors apply a systems based approach to characterise the antibody re
Externí odkaz:
https://doaj.org/article/b3735969bc2442d3bede1a835ba02866
Autor:
Thomas S. Fulford, Huy Van, Nicholas A. Gherardin, Shuning Zheng, Marcin Ciula, Heidi E. Drummer, Samuel Redmond, Hyon-Xhi Tan, Irene Boo, Rob J. Center, Fan Li, Samantha L. Grimley, Bruce D. Wines, Thi H.O. Nguyen, Francesca L. Mordant, Paula Ellenberg, Louise C. Rowntree, Lukasz Kedzierski, Allen C. Cheng, Denise L. Doolan, Gail Matthews, Katherine Bond, P. Mark Hogarth, Zoe McQuilten, Kanta Subbarao, Katherine Kedzierska, Jennifer A. Juno, Adam K. Wheatley, Stephen J. Kent, Deborah A. Williamson, Damian F.J. Purcell, David A. Anderson, Dale I. Godfrey
Publikováno v:
EBioMedicine, Vol 74, Iss , Pp 103729- (2021)
Background: As vaccines against SARS-CoV-2 are now being rolled out, a better understanding of immunity to the virus, whether from infection, or passive or active immunisation, and the durability of this protection is required. This will benefit from
Externí odkaz:
https://doaj.org/article/b797a15ea4c145e7a13177048c7b5ebe