Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Denise Kothe"'
Autor:
Munir Alam, Weimin Liu, Ling Ye, Yuliang Sun, Bao-Zhong Wang, Gale Smith, Peter Pushko, Yingying Li, Sang-Moo Kang, Barton F. Haynes, Chunzi Huang, Terje Dokland, Denise Kothe, Beatrice H. Hahn, Richard W. Compans
Publikováno v:
Journal of Virology. 81:10869-10878
The human immunodeficiency virus (HIV) envelope (Env) protein is incorporated into HIV virions or virus-like particles (VLPs) at very low levels compared to the glycoproteins of most other enveloped viruses. To test factors that influence HIV Env par
Autor:
Julie M. Decker, Frederic Bibollet-Ruche, Kenneth P. Zammit, Zhiping Weng, Bette T. Korber, Denise Kothe, George M. Shaw, Beatrice H. Hahn, Yalu Chen, Barton F. Haynes, Yingying Li, Maria G. Salazar, Feng Gao, Eric A. Weaver
Publikováno v:
Virology. 352(2):438-449
Immunogens based on “centralized” (ancestral or consensus) HIV-1 sequences minimize the genetic distance between vaccine strains and contemporary viruses and should thus elicit immune responses that recognize a broader spectrum of viral variants.
Autor:
Glen A. Satten, W. Harry Hannon, Joanne V. Mei, Robert H. Byers, Denise Kothe, Robert S. Janssen, Samuel P. Caudill
Publikováno v:
JAIDS Journal of Acquired Immune Deficiency Syndromes. 33:625-634
Less sensitive (LS) HIV-1 enzyme immunoassays (EIAs) have significantly improved the quantity and quality of HIV surveillance data. The first LS-HIV-1 EIA, the Abbott 3A11-LS, provided reliable incidence data, but the assay required specialized equip
Autor:
Hillard Weinstock, Monica Dale, Marta Gwinn, Glen A. Satten, Denise Kothe, Joanne Mei, Janet Royalty, Laurie Linley, Carol Fridlund, Bharat Parekh, Bhupat D. Rawal, Michael P. Busch, Robert S. Janssen
Publikováno v:
JAIDS Journal of Acquired Immune Deficiency Syndromes. 29:478-483
Although the numbers of newly reported diagnoses of AIDS decreased in the 1990s, it is not clear whether they reflect a decreasing number of new HIV infections. Direct measurement of HIV incidence through follow-up cohort studies is difficult and cos
Autor:
Julie M. Decker, Jiri Mestecky, Feng Gao, George M. Shaw, Yalu Chen, Bette T. Korber, Beatrice H. Hahn, Kenneth P. Zammit, Zina Moldoveanu, Yingying Li, Jesus F. Salazar-Gonzalez, Frederic Bibollet-Ruche, Denise Kothe, Mark Muldoon, Barton F. Haynes, Maria G. Salazar, Zhiping Weng
Publikováno v:
Virology. (1):218-234
“Centralized” (ancestral and consensus) HIV-1 envelope immunogens induce broadly cross-reactive T cell responses in laboratory animals; however, their potential to elicit cross-reactive neutralizing antibodies has not been fully explored. Here, w