Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Denise K. Grosenbaugh"'
Autor:
Denise K. Grosenbaugh, Suchitra Joshi, Mark P. Fitzgerald, Kevin S. Lee, Pravin K. Wagley, Alexander F. Koeppel, Stephen D. Turner, Michael J. McConnell, Howard P. Goodkin
Publikováno v:
Neurobiology of Disease, Vol 140, Iss , Pp 104836- (2020)
Children with malformations of cortical development (MCD) are at risk for epilepsy, developmental delays, behavioral disorders, and intellectual disabilities. For a subset of these children, antiseizure medications or epilepsy surgery may result in s
Externí odkaz:
https://doaj.org/article/8894f587e3bb4dd4925e35408cf23754
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
Abstract Kainate receptors (KARs) are glutamate receptors with peak expression during late embryonic and early postnatal periods. Altered KAR-mediated neurotransmission and subunit expression are observed in several brain disorders, including epileps
Externí odkaz:
https://doaj.org/article/0428bd9452d54bc9a99c83ee5546e69d
Publikováno v:
Brain research. 1800
The tish (telencephalic internal structural heterotopia) rat is a naturally occurring and unique model of a malformation of cortical development (MCD) arising from a sponeantous mutation in the Eml1 gene. Tish rats are characterized by a macroscopic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78aecb4ca659913b699fcdbb6947bc5c
https://pubmed.ncbi.nlm.nih.gov/36511312
https://pubmed.ncbi.nlm.nih.gov/36511312
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
Scientific Reports
Scientific Reports
Kainate receptors (KARs) are glutamate receptors with peak expression during late embryonic and early postnatal periods. Altered KAR-mediated neurotransmission and subunit expression are observed in several brain disorders, including epilepsy. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e11f16e4da80fe3286ce18e476e1a0c3
https://doaj.org/article/0428bd9452d54bc9a99c83ee5546e69d
https://doaj.org/article/0428bd9452d54bc9a99c83ee5546e69d
Autor:
Stephen D. Turner, Suchitra Joshi, Pravin K Wagley, Denise K. Grosenbaugh, Alexander F. Koeppel, Howard P. Goodkin, Kevin S. Lee, Michael J. McConnell, Mark Fitzgerald
Publikováno v:
Neurobiology of Disease, Vol 140, Iss, Pp 104836-(2020)
Neurobiology of disease
Neurobiology of disease
Children with malformations of cortical development (MCD) are at risk for epilepsy, developmental delays, behavioral disorders, and intellectual disabilities. For a subset of these children, antiseizure medications or epilepsy surgery may result in s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58937884793b7eb5b46f515524ebfbc8
https://doi.org/10.1016/j.nbd.2020.104836
https://doi.org/10.1016/j.nbd.2020.104836
Autor:
David D. Mott, Denise K. Grosenbaugh
Publikováno v:
Neuropharmacology. 67:136-143
Benzodiazepines (BZDs) are first-line therapy for treatment of status epilepticus (SE). However, BZD treatment is negatively affected by seizure duration due to decreases in BZD-sensitive GABA A receptors during prolonged SE. Stiripentol (STP) is an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14d290db3c1cf6dfc3b6a276cf46a98d
https://doi.org/10.1016/j.neuropharm.2012.11.002
https://doi.org/10.1016/j.neuropharm.2012.11.002
Publikováno v:
Neuroscience. 310
Objective: The present study tested the hypothesis that exposure to in vitro hypoxia–ischemia alters membrane properties and excitability as well as excitatory synaptic transmission of CA1 pyramidal neurons in the neonatal mouse. Methods: Experimen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e27f041b717b4f0fadccd1d7650bb0db
https://pubmed.ncbi.nlm.nih.gov/26404876
https://pubmed.ncbi.nlm.nih.gov/26404876
Autor:
Denise K. Grosenbaugh, David D. Mott
Publikováno v:
Epilepsia. 54:103-105
Summary Benzodiazepines (BZDs), which enhance γ-aminobutyric acid (GABAA) receptor–mediated inhibition, are the first-line therapy for treatment of status epilepticus (SE). However, pharmacoresistance to BZDs develops rapidly after SE initiation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ef038d110b04dca6af3fc633a2a5d71
https://doi.org/10.1111/epi.12291
https://doi.org/10.1111/epi.12291
Publikováno v:
Epilepsybehavior : EB. 29(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ed3602b13643db94a9934cdc1b9a177
https://pubmed.ncbi.nlm.nih.gov/23591263
https://pubmed.ncbi.nlm.nih.gov/23591263
The National Center for Complementary and Alternative Medicine (NCCAM) estimates that nearly 40% of adults in the United States use alternative medicines, often in the form of an herbal supplement. Extracts from the tree bark of magnolia species have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f36f79219ed503faf6727be98c7bb59
https://europepmc.org/articles/PMC3652012/
https://europepmc.org/articles/PMC3652012/
