Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Denise Kühnert"'
Autor:
Sama Goliaei, Mohammad-Hadi Foroughmand-Araabi, Aideen Roddy, Ariane Weber, Sanni Översti, Denise Kühnert, Alice C. McHardy
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract During the early stages of the SARS-CoV-2 pandemic, before vaccines were available, nonpharmaceutical interventions (NPIs) such as reducing contacts or antigenic testing were used to control viral spread. Quantifying their success is therefo
Externí odkaz:
https://doaj.org/article/ccf8e440fb694716b128fb4acded21fe
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract SARS-CoV-2 can infect human cells through the recognition of the human angiotensin-converting enzyme 2 receptor. This affinity is given by six amino acid residues located in the variable loop of the receptor binding domain (RBD) within the S
Externí odkaz:
https://doaj.org/article/5aa398d3ae0a4ab8adfb6513e1a1e74b
Autor:
Maureen Rebecca Smith, Maria Trofimova, Ariane Weber, Yannick Duport, Denise Kühnert, Max von Kleist
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
The true number of infections from SARS-Cov-2 is unknown and believed to exceed the reported numbers by several fold. National testing policies, in particular, can strongly affect the proportion of undetected cases. Here, the authors propose a method
Externí odkaz:
https://doaj.org/article/e7c6255639b44145b770b60395daed55
Autor:
Mathilde Boumasmoud, Vanina Dengler Haunreiter, Tiziano A. Schweizer, Lilly Meyer, Bhavya Chakrakodi, Peter W. Schreiber, Kati Seidl, Denise Kühnert, Roger D. Kouyos, Annelies S. Zinkernagel
Publikováno v:
mBio, Vol 13, Iss 2 (2022)
ABSTRACT Healthcare-associated outbreaks of vancomycin-resistant Enterococcus faecium (VREfm) are a worldwide problem with increasing prevalence. The genomic plasticity of this hospital-adapted pathogen contributes to its efficient spread despite inf
Externí odkaz:
https://doaj.org/article/242e68b027514d2da415a17a41637f41
Autor:
Susanna Sabin, Alexander Herbig, Åshild J. Vågene, Torbjörn Ahlström, Gracijela Bozovic, Caroline Arcini, Denise Kühnert, Kirsten I. Bos
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-24 (2020)
Abstract Background Although tuberculosis accounts for the highest mortality from a bacterial infection on a global scale, questions persist regarding its origin. One hypothesis based on modern Mycobacterium tuberculosis complex (MTBC) genomes sugges
Externí odkaz:
https://doaj.org/article/10aeed7bf557409b90db23ff5640aa17
Autor:
Dawit Assefa Arimide, Luis Roger Esquivel-Gómez, Yenew Kebede, Sviataslau Sasinovich, Taye Balcha, Per Björkman, Denise Kühnert, Patrik Medstrand
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
BackgroundEthiopia is one of the sub-Saharan countries hit hard by the HIV epidemic. Previous studies have shown that subtype C dominates the Ethiopian HIV-1 epidemic, but the evolutionary and temporal dynamics of HIV-1 in Ethiopia have not been clos
Externí odkaz:
https://doaj.org/article/d0b81ec78c3a44459515cae76f9252fd
Autor:
Jūlija Pečerska, Denise Kühnert, Conor J. Meehan, Mireia Coscollá, Bouke C. de Jong, Sebastien Gagneux, Tanja Stadler
Publikováno v:
Epidemics, Vol 36, Iss , Pp 100471- (2021)
As multi-drug resistant tuberculosis (MDR-TB) continues to spread, investigating the transmission potential of different drug-resistant strains becomes an ever more pressing topic in public health. While phylogenetic and transmission tree inferences
Externí odkaz:
https://doaj.org/article/13ccf3aee7c54ecd8ad8249858b00cb1
Autor:
Vanina Dengler Haunreiter, Mathilde Boumasmoud, Nicola Häffner, Dennis Wipfli, Nadja Leimer, Carole Rachmühl, Denise Kühnert, Yvonne Achermann, Reinhard Zbinden, Stefano Benussi, Clement Vulin, Annelies S. Zinkernagel
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Staphylococcus epidermidis is a frequent cause of medical implant-associated biofilm infections. Here, studying a patient with pacemaker-associated endocarditis, the authors report in-host evolution of S. epidermidis leading to phenotypes exhibiting
Externí odkaz:
https://doaj.org/article/8fa482bb0c6a4cc980cfed4350010340
Autor:
Franziska Hufsky, Ana Abecasis, Patricia Agudelo-Romero, Magda Bletsa, Katherine Brown, Claudia Claus, Stefanie Deinhardt-Emmer, Li Deng, Caroline C. Friedel, María Inés Gismondi, Evangelia Georgia Kostaki, Denise Kühnert, Urmila Kulkarni-Kale, Karin J. Metzner, Irmtraud M. Meyer, Laura Miozzi, Luca Nishimura, Sofia Paraskevopoulou, Alba Pérez-Cataluña, Janina Rahlff, Emma Thomson, Charlotte Tumescheit, Lia van der Hoek, Lore Van Espen, Anne-Mieke Vandamme, Maryam Zaheri, Neta Zuckerman, Manja Marz
Publikováno v:
Viruses, Vol 14, Iss 7, p 1522 (2022)
Viruses are the cause of a considerable burden to human, animal and plant health, while on the other hand playing an important role in regulating entire ecosystems. The power of new sequencing technologies combined with new tools for processing “Bi
Externí odkaz:
https://doaj.org/article/0d63344a88c745c1b77f5879ac473c63
Publikováno v:
Viruses, Vol 14, Iss 8, p 1648 (2022)
The multi-type birth–death model with sampling is a phylodynamic model which enables the quantification of past population dynamics in structured populations based on phylogenetic trees. The BEAST 2 package bdmm implements an algorithm for numerica
Externí odkaz:
https://doaj.org/article/af5b9d6ae566420685a138019c38acf4